Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Breast cancer type 1 susceptibility protein is a protein that in humans is encoded by the BRCA1 (/ˌbrækəˈwʌn/) gene. Orthologs are common in other vertebrate species, whereas invertebrate genomes may encode a more distantly related gene. BRCA1 is a caretaker gene (responsible for repairing DNA), a type of tumor suppressor gene.
Protein structure, Function and mechanism & Interactions
Explore the main themes, entities and connections around BRCA1. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the full topic structure. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
See the strongest relationship patterns around the current topic before diving into the raw triples.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
dna cancer protein breast mutations repair gene ovarian also expression brca2 may damage mutation myriad cancers double-strand domain proteins role
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| BRCA1 | 2.3.2.27 | ↗ | 1.00 | infobox |
| BRCA1 | Aliases | BRCA1, breast cancer 1, early onset, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53, FANCS, breast cancer 1, DNA repair associated, BRCA1 DNA repair associated, Genes | 1.00 | infobox |
| BRCA1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JM7, 1JNX, 1N5O, 1OQA, 1T15, 1T29, 1T2U, 1T2V, 1Y98, 2ING, 3COJ, 3K0H, 3K0K, 3K15, 3PXA, 3PXB, 3PXC, 3PXD,… | 1.00 | infobox |
| BRCA1 | Band | 17q21.31 | 1.00 | infobox |
| BRCA1 | Band | 11 65.18 cM|11 D | 1.00 | infobox |
| BRCA1 | Bgee | ventricular zone | 1.00 | infobox |
| BRCA1 | Bgee | testicle | 1.00 | infobox |
| BRCA1 | Bgee | gonad | 1.00 | infobox |
| BRCA1 | Bgee | ganglionic eminence | 1.00 | infobox |
| BRCA1 | Bgee | secondary oocyte | 1.00 | infobox |
| BRCA1 | Bgee | bone marrow cell | 1.00 | infobox |
| BRCA1 | Bgee | sural nerve | 1.00 | infobox |
| BRCA1 | Bgee | trabecular bone | 1.00 | infobox |
| BRCA1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| BRCA1 | Bgee | epithelium of colon | 1.00 | infobox |
| BRCA1 | Bgee | primary oocyte | 1.00 | infobox |
| BRCA1 | Bgee | zygote | 1.00 | infobox |
| BRCA1 | Bgee | genital tubercle | 1.00 | infobox |
| BRCA1 | Bgee | tail of embryo | 1.00 | infobox |
| BRCA1 | Bgee | primitive streak | 1.00 | infobox |
| BRCA1 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| BRCA1 | Bgee | maxillary prominence | 1.00 | infobox |
| BRCA1 | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| BRCA1 | Bgee | mandibular prominence | 1.00 | infobox |
| BRCA1 | BioGPS | More reference expression data | 1.00 | infobox |
| BRCA1 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| BRCA1 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| BRCA1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| BRCA1 | End | 43,170,245 bp | 1.00 | infobox |
| BRCA1 | End | 101,442,781 bp | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.