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BRCA2 and BRCA2 (/ˌbrækəˈtuː/) are human genes and their protein products, respectively. The official symbol (BRCA2, italic for the gene, nonitalic for the protein) and the official name (originally breast cancer 2; currently BRCA2, DNA repair associated) are maintained by the HUGO Gene Nomenclature Committee. One alternative symbol, FANCD1, recognizes…
The analysis highlights History and Products as prominent areas in the source structure around BRCA2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around BRCA2 shows recurring relationship patterns in the source. For example, BRCA2 → brain development, BRCA2-MAGE-D1 complex, cell cycle, cell population proliferation, cellular response to DNA damage stimulus, centrosome, centrosome duplication, chordate embryonic development, chromosome organization, cytoplasm, cytoskeleton, cytosol, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA recombination, DNA repair, DNA synthesis involved in double-strand break repair via homologous recombination, double-strand break repair, double-strand break repair via homologous recombination, establishment of protein localization to telomere Another extracted example is BRCA2 → Achilles tendon, ankle joint, bone marrow cell, epiblast, ganglionic eminence, genital tubercle, gonad, granulocyte, mandibular prominence, maxillary prominence, primary oocyte, secondary oocyte, seminiferous tubule, stromal cell of endometrium, tail of embryo, testicle, trabecular bone, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
dna cancer gene protein breast repair brca1 mutations genes human also rad51 meiosis homologous myriad mutation domain found strand chromosome
TTTA extracted 277 structured relationships around BRCA2. Examples in this analysis include BRCA2 → Aliases → BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11, breast cancer 2, DNA repair associated, breast cancer 2, early onset, BRCA2 DNA repair associated, Genes and BRCA2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1N0W, 3EU7. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| BRCA2 | Aliases | BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11, breast cancer 2, DNA repair associated, breast cancer 2, early onset, BRCA2 DNA repair associated, Genes | 1.00 | infobox |
| BRCA2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1N0W, 3EU7 | 1.00 | infobox |
| BRCA2 | Band | 13q13.1 | 1.00 | infobox |
| BRCA2 | Band | 5 G3|5 89.52 cM | 1.00 | infobox |
| BRCA2 | Bgee | testicle | 1.00 | infobox |
| BRCA2 | Bgee | secondary oocyte | 1.00 | infobox |
| BRCA2 | Bgee | ventricular zone | 1.00 | infobox |
| BRCA2 | Bgee | gonad | 1.00 | infobox |
| BRCA2 | Bgee | ganglionic eminence | 1.00 | infobox |
| BRCA2 | Bgee | granulocyte | 1.00 | infobox |
| BRCA2 | Bgee | bone marrow cell | 1.00 | infobox |
| BRCA2 | Bgee | trabecular bone | 1.00 | infobox |
| BRCA2 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| BRCA2 | Bgee | Achilles tendon | 1.00 | infobox |
| BRCA2 | Bgee | primary oocyte | 1.00 | infobox |
| BRCA2 | Bgee | zygote | 1.00 | infobox |
| BRCA2 | Bgee | tail of embryo | 1.00 | infobox |
| BRCA2 | Bgee | epiblast | 1.00 | infobox |
| BRCA2 | Bgee | seminiferous tubule | 1.00 | infobox |
| BRCA2 | Bgee | maxillary prominence | 1.00 | infobox |
| BRCA2 | Bgee | genital tubercle | 1.00 | infobox |
| BRCA2 | Bgee | ankle joint | 1.00 | infobox |
| BRCA2 | Bgee | mandibular prominence | 1.00 | infobox |
| BRCA2 | BioGPS | More reference expression data | 1.00 | infobox |
| BRCA2 | Chr. | Chromosome 13 (human) | 1.00 | infobox |
| BRCA2 | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| BRCA2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| BRCA2 | End | 32,400,268 bp | 1.00 | infobox |
| BRCA2 | End | 150,493,794 bp | 1.00 | infobox |
| BRCA2 | Ensembl | ENSG00000139618 | 1.00 | infobox |
The concept neighborhoods around BRCA2 bring nearby vocabulary together. In this analysis, examples include Dna, Gene and Cancer. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For BRCA2, one of the stronger structural bridges in this analysis connects BRCA2 with Domain architecture. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around BRCA2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Products, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — BRCA2 · EN edition · Analysis: TopicsToTalkAbout