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Histone acetyltransferase p300 also known as p300 HAT or E1A-associated protein p300 (where E1A = adenovirus early region 1A) also known as EP300 or p300 is an enzyme that, in humans, is encoded by the EP300 gene. It functions as histone acetyltransferase that regulates transcription of genes via chromatin remodeling by allowing histone proteins to wrap…
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gene p300 protein chromosome human 22 mutations transcription bp binding chr band histone development cancer acetyltransferase enzyme cells cell function
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| EP300 | 2.3.1.48 | ↗ | 1.00 | infobox |
| EP300 | Aliases | EP300, KAT3B, RSTS2, p300, E1A binding protein p300, MKHK2 | 1.00 | infobox |
| EP300 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1L3E, 1P4Q, 2K8F, 2MH0, 2MZD, 3BIY, 3I3J, 3IO2, 3P57, 3T92, 4BHW, 4PZR, 4PZS, 4PZT, 5BT3 | 1.00 | infobox |
| EP300 | Band | 22q13.2 | 1.00 | infobox |
| EP300 | Band | 15|15 E1 | 1.00 | infobox |
| EP300 | Bgee | epithelium of colon | 1.00 | infobox |
| EP300 | Bgee | bone marrow cell | 1.00 | infobox |
| EP300 | Bgee | lower lobe of lung | 1.00 | infobox |
| EP300 | Bgee | tonsil | 1.00 | infobox |
| EP300 | Bgee | testicle | 1.00 | infobox |
| EP300 | Bgee | visceral pleura | 1.00 | infobox |
| EP300 | Bgee | ventricular zone | 1.00 | infobox |
| EP300 | Bgee | parietal pleura | 1.00 | infobox |
| EP300 | Bgee | corpus callosum | 1.00 | infobox |
| EP300 | Bgee | monocyte | 1.00 | infobox |
| EP300 | Bgee | tail of embryo | 1.00 | infobox |
| EP300 | Bgee | genital tubercle | 1.00 | infobox |
| EP300 | Bgee | gastrula | 1.00 | infobox |
| EP300 | Bgee | zygote | 1.00 | infobox |
| EP300 | Bgee | granulocyte | 1.00 | infobox |
| EP300 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| EP300 | Bgee | hand | 1.00 | infobox |
| EP300 | Bgee | submandibular gland | 1.00 | infobox |
| EP300 | Bgee | spleen | 1.00 | infobox |
| EP300 | Bgee | secondary oocyte | 1.00 | infobox |
| EP300 | BioGPS | More reference expression data | 1.00 | infobox |
| EP300 | Chr. | Chromosome 22 (human) | 1.00 | infobox |
| EP300 | Chr. | Chromosome 15 (mouse) | 1.00 | infobox |
| EP300 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| EP300 | End | 41,180,077 bp | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.