Estrogen receptor alpha: Tissue distribution and function, Interactions & Clinical significance

The extracted context around Estrogen receptor alpha shows recurring relationship patterns in the source. For example, Estrogen receptor alpha → androgen metabolic process, antral ovarian follicle growth, ATPase binding, beta-catenin binding, cellular response to estradiol stimulus, cellular response to estrogen stimulus, chromatin binding, chromatin remodeling, core promoter sequence-specific DNA binding, cytoplasm, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, enzyme binding, epithelial cell development, epithelial cell proliferation involved in mammary gland duct elongation, estrogen receptor activity, estrogen receptor binding Another extracted example is Estrogen receptor alpha → body of uterus, canal of the cervix, cervix epithelium, decidua, ectocervix, efferent ductule, endometrium, epithelium of lactiferous gland, gastrula, intercostal muscle, lactiferous duct, lumbar spinal ganglion, right uterine tube, sternocleidomastoid muscle, temporal muscle, triceps brachii muscle, uterus, vagina, vas deferens, vulva. Use these groups to spot repeated connection types before inspecting the individual relationships.

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

TTTA extracted 155 structured relationships around Estrogen receptor alpha. Examples in this analysis include Estrogen receptor alpha → Aliases → ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1, estrogen receptor 1 and Estrogen receptor alpha → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A52, 1ERE, 1ERR, 1G50, 1GWQ, 1GWR, 1HCP, 1HCQ, 1L2I, 1PCG, 1QKT, 1QKU, 1R5K, 1SJ0, 1UOM, 1X7E, 1X7R, 1XP1,…. The table shows each extracted connection, where it came from and its confidence.

The concept neighborhoods around Estrogen receptor alpha bring nearby vocabulary together. In this analysis, examples include Receptor, Erα and Stimulation. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

For Estrogen receptor alpha, one of the stronger structural bridges in this analysis connects Estrogen receptor alpha with Tissue distribution and function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.