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POLR2A

DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that is encoded by the POLR2A gene in humans.

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2.7.7.48
2.7.7.6
Aliases
POLR2A, POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1, polymerase (RNA) II subunit A, RNA polymerase II subunit A, NEDHIB
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GHQ, 2GHT, 2LTO, 3D9K, 3D9L, 3D9M, 3D9N, 3D9O, 3D9P, 4JXT, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Band
17p13.1 · 11 B3|11 42.86 cM
Bgee
right testis · left testis · stromal cell of endometrium · mucosa of esophagus · skin of leg

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POLR2A

Nodes39
Edges38
Triples125
Avg. degree1.95
Density0.051282
Components1

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POLR2A

Top relations

Gene ontology · 35
POLR2A → 7-methylguanosine mRNA capping, cytoplasm, DNA binding, DNA-directed 5'-3' RNA polymerase activity, DNA-templated transcription, termination, fibroblast growth factor receptor signaling pathway, metal ion binding, mRNA splicing, via spliceosome, nucleolus, nucleoplasm, nucleotidyltransferase activity, nucleus, positive regulation of RNA splicing, positive regulation of viral transcription, promoter-specific chromatin binding, protein binding, protein C-terminus binding, Prp19 complex, regulation of gene silencing by miRNA, regulation of transcription, DNA-templated
related to Interactions · 24
POLR2A → BRCA1, CDK8, CREBBP, CTDP1, GTF2B, GTF2F1, GTF2H4, MED21, MED26, PCAF, POLR2C, POLR2E, POLR2H, POLR2L, PQBP1, SMARCA2, SMARCA4SMARCB1, SMYD3, SND1, SUPT5H
Bgee · 20
POLR2A → epiblast, external carotid artery, genital tubercle, Ileal epithelium, internal carotid artery, left adrenal gland, left testis, mucosa of esophagus, neural layer of retina, perirhinal cortex, pituitary gland, right adrenal cortex, right testis, right uterine tube, skin of abdomen, skin of leg, stromal cell of endometrium, tail of embryo, tracheobronchial tree, ventricular zone
RNA expression pattern · 20
POLR2A → epiblast, external carotid artery, genital tubercle, Ileal epithelium, internal carotid artery, left adrenal gland, left testis, mucosa of esophagus, neural layer of retina, perirhinal cortex, pituitary gland, right adrenal cortex, right testis, right uterine tube, skin of abdomen, skin of leg, stromal cell of endometrium, tail of embryo, tracheobronchial tree, ventricular zone
Band · 2
POLR2A → 11 B3|11 42.86 cM, 17p13.1
Chr. · 2
POLR2A → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
POLR2A → 69,649,463 bp, 7,514,616 bp
2.7.7.48 · 1
POLR2A → ↗
2.7.7.6 · 1
POLR2A → ↗
Aliases · 1
POLR2A → POLR2A, POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1, polymerase (RNA) II subunit A, RNA polymerase II subunit A, NEDHIB

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Important terminology

polymerase bp gene rna chr human band ii chromosome 17 subunit location activity enzyme mouse dna-directed rpb1 function external search

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
POLR2A2.7.7.481.00infobox
POLR2A2.7.7.61.00infobox
POLR2AAliasesPOLR2A, POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1, polymerase (RNA) II subunit A, RNA polymerase II subunit A, NEDHIB1.00infobox
POLR2AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GHQ, 2GHT, 2LTO, 3D9K, 3D9L, 3D9M, 3D9N, 3D9O, 3D9P, 4JXT, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY61.00infobox
POLR2ABand17p13.11.00infobox
POLR2ABand11 B3|11 42.86 cM1.00infobox
POLR2ABgeeright testis1.00infobox
POLR2ABgeeleft testis1.00infobox
POLR2ABgeestromal cell of endometrium1.00infobox
POLR2ABgeemucosa of esophagus1.00infobox
POLR2ABgeeskin of leg1.00infobox
POLR2ABgeeright adrenal cortex1.00infobox
POLR2ABgeeright uterine tube1.00infobox
POLR2ABgeepituitary gland1.00infobox
POLR2ABgeeleft adrenal gland1.00infobox
POLR2ABgeeskin of abdomen1.00infobox
POLR2ABgeeneural layer of retina1.00infobox
POLR2ABgeetail of embryo1.00infobox
POLR2ABgeegenital tubercle1.00infobox
POLR2ABgeeepiblast1.00infobox
POLR2ABgeeventricular zone1.00infobox
POLR2ABgeeinternal carotid artery1.00infobox
POLR2ABgeeIleal epithelium1.00infobox
POLR2ABgeetracheobronchial tree1.00infobox
POLR2ABgeeexternal carotid artery1.00infobox
POLR2ABgeeperirhinal cortex1.00infobox
POLR2ABioGPSMore reference expression data1.00infobox
POLR2AChr.Chromosome 17 (human)1.00infobox
POLR2AChr.Chromosome 11 (mouse)1.00infobox
POLR2ADatabasesNCBI: entry; OMA: entry1.00infobox

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