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Rad50: Function, Evolutionary ancestry & Interactions

DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene.

Language: English [EN]
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Rad50 topic overview

The analysis highlights Function, Evolutionary ancestry and Interactions as prominent areas in the source structure around Rad50.

Related topics
23
Source areas
6
Connected nodes
29
Extracted relationships
148
Concept neighborhoods
13
Bridge connections
29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Evolutionary ancestry · 6 topics
Function · 6 topics
Interactions · 5 topics
Structure · 3 topics
Overview · 2 topics
Diseases · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
RAD50, NBSLD, RAD502, hRad50, Rad50, RAD50 double strand break repair protein
Band
5q31.1 · 11 B1.3|11 31.98 cM
Bgee
corpus callosum · Achilles tendon · epithelium of colon · testicle · gonad
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Structure

Interactions

Evolutionary ancestry

Diseases

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Rad50 connects Entity context

The extracted context around Rad50 shows recurring relationship patterns in the source. For example, Rad50 → 3'-5' exonuclease activity, adenylate kinase activity, ATP binding, ATPase activity, cell cycle, cellular response to DNA damage stimulus, chromosome, chromosome organization involved in meiotic cell cycle, condensed nuclear chromosome, DNA binding, DNA double-strand break processing, DNA duplex unwinding, DNA helicase activity, DNA recombination, DNA repair, DNA replication, DNA synthesis involved in DNA repair, double-strand break repair, double-strand break repair via homologous recombination, double-strand break repair via nonhomologous end joining Another extracted example is Rad50 → Achilles tendon, corpus callosum, epiblast, epithelium of colon, genital tubercle, gonad, Ileal epithelium, internal carotid artery, islet of Langerhans, ovary, Paneth cell, primary oocyte, secondary oocyte, stromal cell of endometrium, sural nerve, tail of embryo, testicle, tonsil, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

Rad50

Top relations

Gene ontology · 53
Rad50 → 3'-5' exonuclease activity, adenylate kinase activity, ATP binding, ATPase activity, cell cycle, cellular response to DNA damage stimulus, chromosome, chromosome organization involved in meiotic cell cycle, condensed nuclear chromosome, DNA binding, DNA double-strand break processing, DNA duplex unwinding, DNA helicase activity, DNA recombination, DNA repair, DNA replication, DNA synthesis involved in DNA repair, double-strand break repair, double-strand break repair via homologous recombination, double-strand break repair via nonhomologous end joining
Bgee · 20
Rad50 → Achilles tendon, corpus callosum, epiblast, epithelium of colon, genital tubercle, gonad, Ileal epithelium, internal carotid artery, islet of Langerhans, ovary, Paneth cell, primary oocyte, secondary oocyte, stromal cell of endometrium, sural nerve, tail of embryo, testicle, tonsil, ventricular zone, zygote
RNA expression pattern · 20
Rad50 → Achilles tendon, corpus callosum, epiblast, epithelium of colon, genital tubercle, gonad, Ileal epithelium, internal carotid artery, islet of Langerhans, ovary, Paneth cell, primary oocyte, secondary oocyte, stromal cell of endometrium, sural nerve, tail of embryo, testicle, tonsil, ventricular zone, zygote
related to Function · 11
Rad50 → DNA, Gene, MRE11, MRX, NBS1, Saccharomyces, The, This, This MRN, Two, Xrs2
related to Evolutionary ancestry · 7
Rad50 → DNA, However, In, It, Mre11, Sulfolobus, These
related to Structure · 7
Rad50 → ABC ATPase, C-termini, DNA, Like, Mre11-Rad50-Nbs1, Results, SMC
related to Interactions · 5
Rad50 → BRCA1, MRE11A, NBN, RINT1, TERF2IP
related to Diseases · 4
Rad50 → Cells, Human RAD50, Nijmegen Breakage Syndrome, Their
Band · 2
Rad50 → 11 B1.3|11 31.98 cM, 5q31.1
Chr. · 2
Rad50 → Chromosome 11 (mouse), Chromosome 5 (human)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein human repair bp dna chromosome chr band also homologous location recombination break mouse complex meiosis function mre11 proteins

Rad50 relationships Subject–Predicate–Object triples

TTTA extracted 148 structured relationships around Rad50. Examples in this analysis include Rad50 → Aliases → RAD50, NBSLD, RAD502, hRad50, Rad50, RAD50 double strand break repair protein and Rad50 → Band → 5q31.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Rad50AliasesRAD50, NBSLD, RAD502, hRad50, Rad50, RAD50 double strand break repair protein1.00infobox
Rad50Band5q31.11.00infobox
Rad50Band11 B1.3|11 31.98 cM1.00infobox
Rad50Bgeecorpus callosum1.00infobox
Rad50BgeeAchilles tendon1.00infobox
Rad50Bgeeepithelium of colon1.00infobox
Rad50Bgeetesticle1.00infobox
Rad50Bgeegonad1.00infobox
Rad50Bgeeislet of Langerhans1.00infobox
Rad50Bgeestromal cell of endometrium1.00infobox
Rad50Bgeeventricular zone1.00infobox
Rad50Bgeetonsil1.00infobox
Rad50Bgeesural nerve1.00infobox
Rad50Bgeetail of embryo1.00infobox
Rad50Bgeegenital tubercle1.00infobox
Rad50Bgeezygote1.00infobox
Rad50Bgeeprimary oocyte1.00infobox
Rad50Bgeesecondary oocyte1.00infobox
Rad50Bgeeinternal carotid artery1.00infobox
Rad50BgeeIleal epithelium1.00infobox
Rad50Bgeeepiblast1.00infobox
Rad50BgeePaneth cell1.00infobox
Rad50Bgeeovary1.00infobox
Rad50BioGPSMore reference expression data1.00infobox
Rad50Chr.Chromosome 5 (human)1.00infobox
Rad50Chr.Chromosome 11 (mouse)1.00infobox
Rad50DatabasesNCBI: entry; OMA: entry1.00infobox
Rad50End132,646,349 bp1.00infobox
Rad50End53,598,146 bp1.00infobox
Rad50EnsemblENSG000001135221.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Rad50 bring nearby vocabulary together. In this analysis, examples include Gene, Repair and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Rad50
    • Gene
    • Repair
    • Human
    • Proteins
    • Homologous
    • Essential
    • Function
    • Meiosis
    • Suggest
    • Ucsc
    • Location
    • Recombination
  • rad50
    • Gene
    • Repair
    • Human
    • Proteins
    • Homologous
    • Essential
    • Function
    • Meiosis
    • Suggest
    • Ucsc
    • Location
    • Recombination
  • protein
    • Repair
    • Function
    • Homologous
    • Rad50
    • Encoded
    • Orthologs
    • Strand
    • Break
    • Gene
    • Known
    • Mre11
    • Complex
  • gene
    • Human
    • Location
    • Mouse
    • Ucsc
    • Rad50
    • Bp
    • Chr
    • Chromosome
    • B1
    • Protein
    • Repair
    • Strand
  • dna double-strand break
    • Double-strand
    • Strand
    • Repair
    • Complex
    • Function
    • Recombination
    • Homologous
    • Location
    • Bp
    • Chr
    • Chromosome
    • Encoded
  • gene knockout
    • Human
    • Location
    • Mouse
    • Ucsc
    • Rad50
    • Bp
    • Chr
    • Chromosome
    • B1
    • Protein
    • Repair
    • Strand
  • function
    • Orthologs
    • Strand
    • Break
    • Protein
    • Repair
    • Location
    • Bp
    • Chr
    • Chromosome
    • Homologous
    • B1
    • Double-strand
  • mrn complex
    • Recombination
    • Double-strand
    • Homologous
    • Mre11
    • Ucsc
    • Yeast
    • Location
    • Dna
    • Human
    • Protein
    • Repair
    • Encoded

Connections between topic areas Semantic bridges

For Rad50, one of the stronger structural bridges in this analysis connects Rad50 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Rad50Function · splits 23 ⟂ 7
Rad50Evolutionary ancestry · splits 23 ⟂ 7
Rad50Interactions · splits 24 ⟂ 6
Rad50Structure · splits 26 ⟂ 4
Rad50Overview · splits 27 ⟂ 3

Map overview Semantic statistics

Rad50

Nodes30
Edges29
Triples148
Avg. degree1.93
Density0.066667
Components1

Source & methodology

TTTA analyzes the structure around Rad50 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Evolutionary ancestry & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Rad50 · EN edition · Analysis: TopicsToTalkAbout

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