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Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family.
The analysis highlights Interactions, Overview and Function as prominent areas in the source structure around STAT1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around STAT1 shows recurring relationship patterns in the source. For example, STAT1 → axon, blood circulation, cadherin binding, CCR5 chemokine receptor binding, cellular response to cytokine stimulus, cellular response to insulin stimulus, cellular response to interferon-beta, cellular response to interferon-gamma, cellular response to organic cyclic compound, cytokine-mediated signaling pathway, cytoplasm, cytosol, defense response, defense response to virus, dendrite, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, double-stranded DNA binding Another extracted example is STAT1 → All STAT, C-terminus, EGF, Epidermal Growth Factor, Factor, IFN-ß, IFN-α, IFN-γ-dependent, IFNα, IFNγ, IL-27, IL-6, Interferon, Interleukin, ISGF3G/IRF-9, Jak, JAK1, PDGF, Platelet Derived Growth Factor, Specifically STAT1. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
patients mutation infections human bp gene response viral function factor protein chr band also caused cmc type interferons bacterial signal
TTTA extracted 211 structured relationships around STAT1. Examples in this analysis include STAT1 → Aliases → STAT1, CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, signal transducer and activator of transcription 1 and STAT1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3WWT, 1BF5, 1YVL, 2KA6. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| STAT1 | Aliases | STAT1, CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, signal transducer and activator of transcription 1 | 1.00 | infobox |
| STAT1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3WWT, 1BF5, 1YVL, 2KA6 | 1.00 | infobox |
| STAT1 | Band | 2q32.2 | 1.00 | infobox |
| STAT1 | Band | 1 C1.1|1 26.81 cM | 1.00 | infobox |
| STAT1 | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| STAT1 | Bgee | appendix | 1.00 | infobox |
| STAT1 | Bgee | mononuclear cell | 1.00 | infobox |
| STAT1 | Bgee | monocyte | 1.00 | infobox |
| STAT1 | Bgee | decidua | 1.00 | infobox |
| STAT1 | Bgee | endothelial cell | 1.00 | infobox |
| STAT1 | Bgee | lymph node | 1.00 | infobox |
| STAT1 | Bgee | glomerulus | 1.00 | infobox |
| STAT1 | Bgee | granulocyte | 1.00 | infobox |
| STAT1 | Bgee | metanephric glomerulus | 1.00 | infobox |
| STAT1 | Bgee | thymus | 1.00 | infobox |
| STAT1 | Bgee | spleen | 1.00 | infobox |
| STAT1 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| STAT1 | Bgee | gastrula | 1.00 | infobox |
| STAT1 | Bgee | submandibular gland | 1.00 | infobox |
| STAT1 | Bgee | blood | 1.00 | infobox |
| STAT1 | Bgee | epithelium of lens | 1.00 | infobox |
| STAT1 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| STAT1 | Bgee | mucous cell of stomach | 1.00 | infobox |
| STAT1 | BioGPS | More reference expression data | 1.00 | infobox |
| STAT1 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| STAT1 | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| STAT1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| STAT1 | End | 191,020,960 bp | 1.00 | infobox |
| STAT1 | End | 52,201,024 bp | 1.00 | infobox |
| STAT1 | Ensembl | ENSG00000115415 | 1.00 | infobox |
The concept neighborhoods around STAT1 bring nearby vocabulary together. In this analysis, examples include Function, Mutation and Deficiency. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For STAT1, one of the stronger structural bridges in this analysis connects STAT1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around STAT1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Overview & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — STAT1 · EN edition · Analysis: TopicsToTalkAbout