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BRCC3: Interactions, Function & Overview

Lys-63-specific deubiquitinase BRCC36 is an enzyme that in humans is encoded by the BRCC3 gene.

Language: English [EN]
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BRCC3 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around BRCC3.

Related topics
13
Source areas
3
Connected nodes
16
Extracted relationships
111
Concept neighborhoods
9
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics
Function · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BRCC3, BRCC36, C6.1A, CXorf53, BRCA1/BRCA2-containing complex subunit 3
Band
Xq28 · X|X A7.3
Bgee
parotid gland · oral cavity · buccal mucosa cell · mucosa of sigmoid colon · corpus epididymis
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How BRCC3 connects Entity context

The extracted context around BRCC3 shows recurring relationship patterns in the source. For example, BRCC3 → BRCA1-A complex, BRISC complex, cell cycle, cell division, cellular response to DNA damage stimulus, chromatin organization, cytoplasm, cytoskeleton, cytosol, DNA repair, double-strand break repair, double-strand break repair via nonhomologous end joining, enzyme regulator activity, histone H2A K63-linked deubiquitination, hydrolase activity, Lys63-specific deubiquitinase activity, metal ion binding, metallopeptidase activity, mitotic G2 DNA damage checkpoint signaling, nuclear ubiquitin ligase complex Another extracted example is BRCC3 → biceps brachii, bronchial epithelial cell, buccal mucosa cell, corpus epididymis, facial motor nucleus, gastrula, genital tubercle, islet of Langerhans, medial vestibular nucleus, mucosa of sigmoid colon, oral cavity, otic placode, otic vesicle, parotid gland, primitive streak, rectum, seminal vesicula, Skeletal muscle tissue of biceps brachii, submandibular gland, tail of embryo. Use these groups to spot repeated connection types before inspecting the individual relationships.

BRCC3

Top relations

Gene ontology · 35
BRCC3 → BRCA1-A complex, BRISC complex, cell cycle, cell division, cellular response to DNA damage stimulus, chromatin organization, cytoplasm, cytoskeleton, cytosol, DNA repair, double-strand break repair, double-strand break repair via nonhomologous end joining, enzyme regulator activity, histone H2A K63-linked deubiquitination, hydrolase activity, Lys63-specific deubiquitinase activity, metal ion binding, metallopeptidase activity, mitotic G2 DNA damage checkpoint signaling, nuclear ubiquitin ligase complex
Bgee · 20
BRCC3 → biceps brachii, bronchial epithelial cell, buccal mucosa cell, corpus epididymis, facial motor nucleus, gastrula, genital tubercle, islet of Langerhans, medial vestibular nucleus, mucosa of sigmoid colon, oral cavity, otic placode, otic vesicle, parotid gland, primitive streak, rectum, seminal vesicula, Skeletal muscle tissue of biceps brachii, submandibular gland, tail of embryo
RNA expression pattern · 20
BRCC3 → biceps brachii, bronchial epithelial cell, buccal mucosa cell, corpus epididymis, facial motor nucleus, gastrula, genital tubercle, islet of Langerhans, medial vestibular nucleus, mucosa of sigmoid colon, oral cavity, otic placode, otic vesicle, parotid gland, primitive streak, rectum, seminal vesicula, Skeletal muscle tissue of biceps brachii, submandibular gland, tail of embryo
related to Repair of DNA damage · 8
BRCC3 → BRCA1, BRCA1-A, BRCC36, DNA, HR, NHEJ, Sequestration, The
related to Interactions · 6
BRCC3 → BARD1, BRCA1, BRCA2, BRE, P53, RAD51
Band · 2
BRCC3 → Xq28, X|X A7.3
Chr. · 2
BRCC3 → X chromosome (human), X chromosome (mouse)
End · 2
BRCC3 → 155,123,077 bp, 74,497,607 bp
related to External links · 2
BRCC3 → Human BRCC3, UCSC Genome Browser
Aliases · 1
BRCC3 → BRCC3, BRCC36, C6.1A, CXorf53, BRCA1/BRCA2-containing complex subunit 3

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp human chr band brca1 repair dna damage chromosome location complex enzyme brca1-a brcc36 protein end mouse deubiquitinase function

BRCC3 relationships Subject–Predicate–Object triples

TTTA extracted 111 structured relationships around BRCC3. Examples in this analysis include BRCC3 → Aliases → BRCC3, BRCC36, C6.1A, CXorf53, BRCA1/BRCA2-containing complex subunit 3 and BRCC3 → Band → Xq28. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
BRCC3AliasesBRCC3, BRCC36, C6.1A, CXorf53, BRCA1/BRCA2-containing complex subunit 31.00infobox
BRCC3BandXq281.00infobox
BRCC3BandX|X A7.31.00infobox
BRCC3Bgeeparotid gland1.00infobox
BRCC3Bgeeoral cavity1.00infobox
BRCC3Bgeebuccal mucosa cell1.00infobox
BRCC3Bgeemucosa of sigmoid colon1.00infobox
BRCC3Bgeecorpus epididymis1.00infobox
BRCC3Bgeebiceps brachii1.00infobox
BRCC3Bgeerectum1.00infobox
BRCC3BgeeSkeletal muscle tissue of biceps brachii1.00infobox
BRCC3Bgeebronchial epithelial cell1.00infobox
BRCC3Bgeeislet of Langerhans1.00infobox
BRCC3Bgeetail of embryo1.00infobox
BRCC3Bgeegenital tubercle1.00infobox
BRCC3Bgeeotic placode1.00infobox
BRCC3Bgeeprimitive streak1.00infobox
BRCC3Bgeegastrula1.00infobox
BRCC3Bgeefacial motor nucleus1.00infobox
BRCC3Bgeemedial vestibular nucleus1.00infobox
BRCC3Bgeeotic vesicle1.00infobox
BRCC3Bgeesubmandibular gland1.00infobox
BRCC3Bgeeseminal vesicula1.00infobox
BRCC3BioGPSMore reference expression data1.00infobox
BRCC3Chr.X chromosome (human)1.00infobox
BRCC3Chr.X chromosome (mouse)1.00infobox
BRCC3DatabasesNCBI: entry; OMA: entry1.00infobox
BRCC3End155,123,077 bp1.00infobox
BRCC3End74,497,607 bp1.00infobox
BRCC3EnsemblENSG000001855151.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around BRCC3 bring nearby vocabulary together. In this analysis, examples include Gene, Brcc36 and Complex. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • BRCC3
    • Gene
    • Brcc36
    • Complex
    • Enzyme
    • Location
    • Human
    • Deubiquitinase
    • Function
    • Subunit
    • Protein
    • Brca1-a
    • Chromosome
  • brcc3
    • Gene
    • Brcc36
    • Complex
    • Enzyme
    • Location
    • Human
    • Deubiquitinase
    • Function
    • Subunit
    • Protein
    • Brca1-a
    • Chromosome
  • enzyme
    • Complex
    • Gene
    • Protein
    • Brca1-a
    • Ligase
    • Ubiquitin
    • A7
    • Cell
    • Cellular
    • Checkpoint
    • Double-strand
    • Function
  • dna double-strand breaks
    • Damage
    • Repair
    • Brca1
    • Brca1-a
    • Ligase
    • Ubiquitin
    • Cell
    • Double-strand
    • Function
    • Joining
    • Subunit
    • Complex
  • function
    • Subunit
    • Complex
    • Chromosome
    • External
    • Ligase
    • Location
    • Ubiquitin
    • Bp
    • Chr
    • Damage
    • Dna
    • Human
  • gene
    • Location
    • Human
    • A7
    • Mouse
    • Subunit
    • End
    • Protein
    • Band
    • Brca1-a
    • Repair
    • Ligase
    • Ubiquitin
  • non-homologous end joining
    • Cell
    • Joining
    • Mouse
    • Ligase
    • Ubiquitin
    • Location
    • Repair
    • G2
    • Human
    • Radiation
    • Response
    • Subunit
  • brca1
    • Damage
    • Dna
    • Repair
    • Brca1-a
    • Brcc3
    • External
    • Cell
    • Double-strand
    • Function
    • Joining
    • Subunit
    • Brcc36

Connections between topic areas Semantic bridges

For BRCC3, one of the stronger structural bridges in this analysis connects BRCC3 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
BRCC3Interactions · splits 9 ⟂ 8
BRCC3Function · splits 12 ⟂ 5
BRCC3Overview · splits 14 ⟂ 3

Map overview Semantic statistics

BRCC3

Nodes17
Edges16
Triples111
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around BRCC3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — BRCC3 · EN edition · Analysis: TopicsToTalkAbout

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