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DNA mismatch repair protein Msh2 also known as MutS homolog 2 or MSH2 is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome 2. MSH2 is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein, MSH2, which forms a heterodimer with MSH6 to make the human MutSα…
Epigenetic MSH2 deficiencies in cancer, Interactions & Clinical significance
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dna repair mutations gene mismatch msh6 protein mutsα cancer human complex chromosome microsatellite bp instability damage genes msh3 chr band
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MSH2 | Aliases | MSH2, mutS homolog 2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2, hMMRCS2, MSH-2 | 1.00 | infobox |
| MSH2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O8B, 2O8C, 2O8D, 2O8E, 2O8F, 3THW, 3THX, 3THY, 3THZ | 1.00 | infobox |
| MSH2 | Band | 2p21-p16.3 | 1.00 | infobox |
| MSH2 | Band | 17 E4|17 57.87 cM | 1.00 | infobox |
| MSH2 | Bgee | secondary oocyte | 1.00 | infobox |
| MSH2 | Bgee | ventricular zone | 1.00 | infobox |
| MSH2 | Bgee | ganglionic eminence | 1.00 | infobox |
| MSH2 | Bgee | gonad | 1.00 | infobox |
| MSH2 | Bgee | retinal pigment epithelium | 1.00 | infobox |
| MSH2 | Bgee | testicle | 1.00 | infobox |
| MSH2 | Bgee | middle frontal gyrus | 1.00 | infobox |
| MSH2 | Bgee | Brodmann area 10 | 1.00 | infobox |
| MSH2 | Bgee | rectum | 1.00 | infobox |
| MSH2 | Bgee | cerebellar hemisphere | 1.00 | infobox |
| MSH2 | Bgee | primitive streak | 1.00 | infobox |
| MSH2 | Bgee | saccule | 1.00 | infobox |
| MSH2 | Bgee | epiblast | 1.00 | infobox |
| MSH2 | Bgee | otic placode | 1.00 | infobox |
| MSH2 | Bgee | otic vesicle | 1.00 | infobox |
| MSH2 | Bgee | tail of embryo | 1.00 | infobox |
| MSH2 | Bgee | somite | 1.00 | infobox |
| MSH2 | Bgee | zygote | 1.00 | infobox |
| MSH2 | Bgee | abdominal wall | 1.00 | infobox |
| MSH2 | BioGPS | More reference expression data | 1.00 | infobox |
| MSH2 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| MSH2 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| MSH2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MSH2 | End | 47,663,146 bp | 1.00 | infobox |
| MSH2 | End | 88,031,141 bp | 1.00 | infobox |
| MSH2 | Ensembl | ENSG00000095002 | 1.00 | infobox |
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