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Research this topic
Explore the main themes, entities and connections around AKT1. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Interactions
31 related topics
Function
15 related topics
History
5 related topics
Overview
6 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 2.7.11.1
- ↗
- Aliases
- AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, AKT serine/threonine kinase 1
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H10, 1UNP, 1UNQ, 1UNR, 2UVM, 2UZR, 2UZS, 3CQU, 3CQW, 3MV5, 3MVH, 3O96, 3OCB, 3OW4, 3QKK, 3QKL, 3QKM, 4EJN,…
- Band
- 14q32.33 · 12 F1|12 61.2 cM
- Bgee
- stromal cell of endometrium · ganglionic eminence · left adrenal cortex · right adrenal gland · right adrenal cortex
- BioGPS
- More reference expression data
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
- Enzyme
- Gene
- AKT Protein kinase B
- Serine/threonine kinases
- SH2 SH2 domain
- Protein domains Protein domain
Function
- Serine-threonine protein kinase
- Fibroblasts Fibroblast
- AKT2
- Platelet
- Growth factor
- Pleckstrin homology domain
- Phosphatidylinositol 3-kinase
- Nervous system
- Apoptosis
- Phosphorylates Phosphorylate
- IGF1 Insulin-like growth factor 1
- Large T antigen
- Neu oncogene HER2/neu
- Single-nucleotide polymorphism
- Proteus syndrome
History
- Oncogene
- Retrovirus
- Thymoma
- AKR mice AKR mice?action=edit&redlink=1
- Elephant Man Joseph Merrick
Interactions
- Interact Protein-protein interaction
- AKTIP
- BRAF BRAF (gene)
- BRCA1
- C-Raf
- CDKN1B
- CHUK
- GAB2
- HSP90AA1 Heat shock protein 90kDa alpha (cytosolic), member A1
- ILK Integrin-linked kinase
- KRT10 Keratin 10
- MAP2K4
- MAP3K11
- MAP3K8
- MAPK14
- MAPKAPK2
- MARK2
- MTCP1
- MTOR Mammalian target of rapamycin
- NPM1
- NR4A1 Nerve Growth factor IB
- NR3C4 Androgen receptor
- PKN2
- PRKCQ
- PDPK1 Phosphoinositide-dependent kinase-1
- PLXNA1 Plexin A1
- TCL1A
- TRIB3
- TSC1
- TSC2
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.AKT1
Nodes62
Edges61
Triples307
Avg. degree1.97
Density0.032258
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
AKT1
Top relations
Gene ontology · 189
AKT1 → 14-3-3 protein binding, activation of protein kinase B activity, activation-induced cell death of T cells, ageing, anoikis, apoptotic mitochondrial changes, apoptotic process, ATP binding, calmodulin binding, carbohydrate metabolic process, carbohydrate transport, cell differentiation, cell migration involved in sprouting angiogenesis, cell population proliferation, cell projection organization, cell-cell junction, cellular response to cadmium ion, cellular response to decreased oxygen levels, cellular response to DNA damage stimulus, cellular response to epidermal growth factor stimulus
related to Interactions · 28
AKT1 → AKTIP, BRAF, BRCA1, C-Raf, CDKN1B, CHUKGAB2, HSP90AA1, ILK, KRT10, MAP2K4, MAP3K11, MAP3K8, MAPK14, MAPKAPK2, MARK2, MTCP1, MTOR, NPM1, NR3C4, NR4A1
Bgee · 19
AKT1 → atrium, body of stomach, efferent ductule, endothelial cell of lymphatic vessel, gallbladder, ganglionic eminence, granulocyte, human fetus, left adrenal cortex, lip, molar, muscle layer of sigmoid colon, right adrenal cortex, right adrenal gland, right coronary artery, stroma of bone marrow, stromal cell of endometrium, submandibular gland, ventricular zone
RNA expression pattern · 19
AKT1 → atrium, body of stomach, efferent ductule, endothelial cell of lymphatic vessel, gallbladder, ganglionic eminence, granulocyte, human fetus, left adrenal cortex, lip, molar, muscle layer of sigmoid colon, right adrenal cortex, right adrenal gland, right coronary artery, stroma of bone marrow, stromal cell of endometrium, submandibular gland, ventricular zone
related to history · 12
AKT1 → AKR, AKT, Akt2, AKT8, Elephant Man, In, Johns Hopkins Oncology Center, Proteus, Rowe, Stephen Staal, The, Wallace
related to Function · 11
AKT1 → AKT, AKT2, IGF1, In, It, Mice, Neu, Proteus, Survival, The, They
related to External links · 4
AKT1 → AKT1 Reference ControlsHuman AKT1, AKT1 Standards, Learn, UCSC Genome Browser
Band · 2
AKT1 → 12 F1|12 61.2 cM, 14q32.33
Chr. · 2
AKT1 → Chromosome 12 (mouse), Chromosome 14 (human)
End · 2
AKT1 → 104,795,751 bp, 112,641,318 bp
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
akt human bp gene serine enzyme chr band mice kinase threonine chromosome 14 mouse location akt2 transforming growth protein also
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| AKT1 | 2.7.11.1 | ↗ | 1.00 | infobox |
| AKT1 | Aliases | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, AKT serine/threonine kinase 1 | 1.00 | infobox |
| AKT1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H10, 1UNP, 1UNQ, 1UNR, 2UVM, 2UZR, 2UZS, 3CQU, 3CQW, 3MV5, 3MVH, 3O96, 3OCB, 3OW4, 3QKK, 3QKL, 3QKM, 4EJN,… | 1.00 | infobox |
| AKT1 | Band | 14q32.33 | 1.00 | infobox |
| AKT1 | Band | 12 F1|12 61.2 cM | 1.00 | infobox |
| AKT1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| AKT1 | Bgee | ganglionic eminence | 1.00 | infobox |
| AKT1 | Bgee | left adrenal cortex | 1.00 | infobox |
| AKT1 | Bgee | right adrenal gland | 1.00 | infobox |
| AKT1 | Bgee | right adrenal cortex | 1.00 | infobox |
| AKT1 | Bgee | ventricular zone | 1.00 | infobox |
| AKT1 | Bgee | right coronary artery | 1.00 | infobox |
| AKT1 | Bgee | gallbladder | 1.00 | infobox |
| AKT1 | Bgee | body of stomach | 1.00 | infobox |
| AKT1 | Bgee | muscle layer of sigmoid colon | 1.00 | infobox |
| AKT1 | Bgee | granulocyte | 1.00 | infobox |
| AKT1 | Bgee | atrium | 1.00 | infobox |
| AKT1 | Bgee | molar | 1.00 | infobox |
| AKT1 | Bgee | human fetus | 1.00 | infobox |
| AKT1 | Bgee | efferent ductule | 1.00 | infobox |
| AKT1 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| AKT1 | Bgee | submandibular gland | 1.00 | infobox |
| AKT1 | Bgee | stroma of bone marrow | 1.00 | infobox |
| AKT1 | Bgee | lip | 1.00 | infobox |
| AKT1 | BioGPS | More reference expression data | 1.00 | infobox |
| AKT1 | Chr. | Chromosome 14 (human) | 1.00 | infobox |
| AKT1 | Chr. | Chromosome 12 (mouse) | 1.00 | infobox |
| AKT1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| AKT1 | End | 104,795,751 bp | 1.00 | infobox |
| AKT1 | End | 112,641,318 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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