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MicroRNA: History & Applications

Micro ribonucleic acid (microRNA, miRNA, μRNA) are small, single-stranded, non-coding RNA molecules containing 21–23 nucleotides. Found in plants, animals, and even some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in messenger RNA (mRNA) molecules, then…

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MicroRNA topic overview

The analysis highlights History and Applications as prominent areas in the source structure around MicroRNA. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics
248
Source areas
13
Connected nodes
262
Extracted relationships
68
Concept neighborhoods
51
Bridge connections
262

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Human and animal diseases · 79 topics
Overview · 55 topics
Biogenesis · 34 topics
Cellular functions · 20 topics
RNA-induced silencing complex · 14 topics
Evolution · 11 topics
Experimental detection and manipulation · 11 topics
History · 10 topics
Turnover · 6 topics
Viruses · 4 topics
Plants · 3 topics
Nomenclature · 1 topics
Target prediction · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History

Nomenclature

Biogenesis

RNA-induced silencing complex

Turnover

Cellular functions

Evolution

Experimental detection and manipulation

Human and animal diseases

Plants

Viruses

Target prediction

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MicroRNA connects Entity context

The extracted context around MicroRNA shows recurring relationship patterns in the source. For example, MicroRNA → Animal, Drosophila, For, In, Partially, Perfect, Recent, RNA, RNAs, The, This, UTR, While Another extracted example is MicroRNA → For, LNA, Morpholino, O-methyl RNA, PCR, RNase-free, RNases, RT-PCR, The, This, Variations, While. Use these groups to spot repeated connection types before inspecting the individual relationships.

MicroRNA

Top relations

related to Cellular functions · 13
MicroRNA → Animal, Drosophila, For, In, Partially, Perfect, Recent, RNA, RNAs, The, This, UTR, While
related to Experimental detection and manipulation · 12
MicroRNA → For, LNA, Morpholino, O-methyl RNA, PCR, RNase-free, RNases, RT-PCR, The, This, Variations, While
related to DNA repair and cancer · 11
MicroRNA → Among, Cancer, CpG, Defects, DNA, Germline, However, Many, MLH1, MLH1-deficiencies, Several
related to External links · 11
MicroRNA → An, ChIP-seq, ChIPBase, Integrative, IO, March, MirOB Archived, ONCO, The, Wayback Machine, Web
related to RNA-induced silencing complex · 6
MicroRNA → Dicer, Generally, In, RISC, RNA-induced, The
see also · 5
MicroRNA → Anti-miRNA, Biology, BiosensorsMiRNESTMIR222miR-324-5pMir-M7, RNA-derived, RNASmall
related to Evolution · 4
MicroRNA → Rapid, RNAi, Their, While
related to Viruses · 4
MicroRNA → DNA, Hence, The, Viral

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mirnas mirna expression gene mrna also rna genes target micrornas may found human cells protein role many dna regulation development

MicroRNA relationships Subject–Predicate–Object triples

TTTA extracted 68 structured relationships around MicroRNA. Examples in this analysis include viruses → instance of → miRNA repertoires in the two kingdoms appear to have emerged independently with different primary modes of action.microRNAs are useful phylogenetic markers because of their appa… and the relationships of arthropods → instance of → and they are being looked upon as a possible solution to outstanding phylogenetic problems. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
virusesinstance ofmiRNA repertoires in the two kingdoms appear to have emerged independently with different primary modes of action.microRNAs are useful phylogenetic markers because of their appa…0.80text
the relationships of arthropodsinstance ofand they are being looked upon as a possible solution to outstanding phylogenetic problems0.80text
MicroRNArelated to Cellular functionsThe0.60section
MicroRNArelated to Cellular functionsFor0.60section
MicroRNArelated to Cellular functionsRNAs0.60section
MicroRNArelated to Cellular functionsAnimal0.60section
MicroRNArelated to Cellular functionsUTR0.60section
MicroRNArelated to Cellular functionsPerfect0.60section
MicroRNArelated to Cellular functionsRNA0.60section
MicroRNArelated to Cellular functionsThis0.60section
MicroRNArelated to Cellular functionsIn0.60section
MicroRNArelated to Cellular functionsPartially0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around MicroRNA bring nearby vocabulary together. In this analysis, examples include Micrornas, Small and Also. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MicroRNA
    • Micrornas
    • Small
    • Also
    • Rnas
    • Expression
    • Mirna
    • Found
    • Animals
    • Target
    • Function
    • Levels
    • One
  • microrna
    • Micrornas
    • Small
    • Also
    • Rnas
    • Expression
    • Mirna
    • Found
    • Animals
    • Target
    • Function
    • Levels
    • One
  • non-coding rna
    • Small
    • Rnas
    • One
    • Protein
    • Animals
    • Mrna
    • Complex
    • Target
    • Hairpin
    • Mirnas
    • Dna
    • Human
  • rna silencing
    • Small
    • Rnas
    • One
    • Protein
    • Animals
    • Mrna
    • Complex
    • Target
    • Hairpin
    • Mirnas
    • Dna
    • Human
  • regulation of gene expression
    • Gene
    • Regulation
    • Role
    • Genes
    • Protein
    • Mirnas
    • Micrornas
    • Dna
    • Function
    • Mirna
    • Levels
    • Development
  • messenger rna
    • Small
    • Rnas
    • One
    • Protein
    • Animals
    • Mrna
    • Complex
    • Target
    • Hairpin
    • Mirnas
    • Dna
    • Human
  • rna interference (rnai)
    • Small
    • Rnas
    • One
    • Protein
    • Animals
    • Mrna
    • Complex
    • Target
    • Hairpin
    • Mirnas
    • Dna
    • Human
  • double-stranded rna
    • Small
    • Rnas
    • One
    • Protein
    • Animals
    • Mrna
    • Complex
    • Target
    • Hairpin
    • Mirnas
    • Dna
    • Human

Connections between topic areas Semantic bridges

For MicroRNA, one of the stronger structural bridges in this analysis connects MicroRNA with Human and animal diseases. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MicroRNA — Human and animal diseases · splits 183 ⟂ 80
MicroRNA — Overview · splits 207 ⟂ 56
MicroRNA — Biogenesis · splits 228 ⟂ 35
MicroRNA — Cellular functions · splits 242 ⟂ 21
MicroRNA — RNA-induced silencing complex · splits 248 ⟂ 15
MicroRNA — Evolution · splits 251 ⟂ 12
MicroRNA — Experimental detection and manipulation · splits 251 ⟂ 12
MicroRNA — History · splits 252 ⟂ 11
MicroRNA — Turnover · splits 256 ⟂ 7
MicroRNA — Viruses · splits 258 ⟂ 5
MicroRNA — Plants · splits 259 ⟂ 4

Map overview Semantic statistics

MicroRNA

Nodes263
Edges262
Triples68
Avg. degree1.99
Density0.007605
Components1

Source & methodology

TTTA analyzes the structure around MicroRNA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MicroRNA · EN edition · Analysis: TopicsToTalkAbout

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