Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Methylation: Science, In biology & In chemistry

Methylation, in the chemical sciences, is the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form of alkylation, with a methyl group replacing a hydrogen atom. These terms are commonly used in chemistry, biochemistry, soil science, and biology.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Methylation topic overview

The analysis highlights Science, In biology and In chemistry as prominent areas in the source structure around Methylation. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics
117
Source areas
5
Connected nodes
123
Extracted relationships
79
Concept neighborhoods
39
Bridge connections
123

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 53 topics
In chemistry · 32 topics
In biology · 22 topics
Organic chemistry topics · 6 topics
Biology topics · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

In biology

In chemistry

Biology topics

Organic chemistry topics

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Methylation connects Entity context

The extracted context around Methylation shows recurring relationship patterns in the source. For example, Methylation → For, Less, Methylations, RO, ROCH3, SN2, The Purdie, These Another extracted example is Methylation → CoA O-methyltransferase, Examples, O-methylation, O-methylgenistein, O-methylmyricetin, O-methylquercetin, Plants, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Methylation

Top relations

related to Electrophilic methylation · 8
Methylation → For, Less, Methylations, RO, ROCH3, SN2, The Purdie, These
related to O-methyltransferases · 8
Methylation → CoA O-methyltransferase, Examples, O-methylation, O-methylgenistein, O-methylmyricetin, O-methylquercetin, Plants, This
related to Proteins · 7
Methylation → Along, N-methylarginine, N-methylhistidine, Otherwise, S-methylcysteine, Some, The
related to In biology · 6
Methylation → B12, In, It, RNA, S-methylmethionine, Sources
related to Nucleophilic methylation · 6
Methylation → CH3Li, CH3MgX, For, Grignard, Milder, Strongly
is a · 5
Methylation → conversion of the cytosine to 5-methylcytosine, form of alkylation, major biochemical process for modifying protein function, specific for the methylation at oxygen of carbohydrates using iodomethane and silver oxide, specific for the methylation at oxygen of carbohydrates using iodomethane and silver oxide.Eschweiler
related to Eschweiler–Clarke methylation · 5
Methylation → CH2, Clarke, The, The Eschweiler, This
related to Heavy metals: arsenic, mercury, cadmium · 5
Methylation → Biomethylation, Related, S-adenosyl, The, Thus
related to Biology topics · 4
Methylation → Bisulfite, DNA, DNA Methylation DatabaseMicroscale, DNARemethylation
related to Methanogenesis · 4
Methylation → CO2, In, Methanogenesis, These

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

methyl dna rna protein group methionine groups methylated enzymes catalyzed chemistry heavy also nucleophilic histones process include reaction methylations human

Methylation relationships Subject–Predicate–Object triples

TTTA extracted 79 structured relationships around Methylation. Examples in this analysis include Methylation → is a → form of alkylation and Methylation → is a → major biochemical process for modifying protein function. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Methylationis aform of alkylation0.90text
Methylationis amajor biochemical process for modifying protein function0.90text
Methylationis aconversion of the cytosine to 5-methylcytosine0.90text
Methylationis aspecific for the methylation at oxygen of carbohydrates using iodomethane and silver oxide.Eschweiler0.90text
Methylationis aspecific for the methylation at oxygen of carbohydrates using iodomethane and silver oxide0.90text
RNA stabilityinstance ofRecent data strongly suggest that m6A and 5-mC RNA methylation affects the regulation of various biological processes0.80text
mRNA translationinstance ofRecent data strongly suggest that m6A and 5-mC RNA methylation affects the regulation of various biological processes0.80text
and that abnormal RNA methylation contributes to etiology of human diseases.In social insects such as honey beesinstance ofRecent data strongly suggest that m6A and 5-mC RNA methylation affects the regulation of various biological processes0.80text
RNA methylation is studied as a possible epigenetic mechanism underlying aggression via reciprocal crosses.Protein methylationProtein methylation typically takes place on arginine or lysine amino acid residues in the protein sequenceinstance ofRecent data strongly suggest that m6A and 5-mC RNA methylation affects the regulation of various biological processes0.80text
RNA methylation is studied as a possible epigenetic mechanism underlying aggression via reciprocal crossesinstance ofRecent data strongly suggest that m6A and 5-mC RNA methylation affects the regulation of various biological processes0.80text
iodomethaneinstance ofCH3 group.Electrophilic methylationMethylations are commonly performed using electrophilic methyl sources0.80text
dimethyl sulfateinstance ofCH3 group.Electrophilic methylationMethylations are commonly performed using electrophilic methyl sources0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Methylation bring nearby vocabulary together. In this analysis, examples include Dna, Rna and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • chemistry
    • Biology
    • Used
    • Methionine
    • Group
    • Arsenic
    • Commonly
    • Diazomethane
    • Metals
    • Methanogenesis
    • Also
    • Biological
    • Dna
  • methyl group
    • Alkylation
    • Group
    • Groups
    • Methyl
    • Used
    • Chemistry
    • Enzyme
    • Form
    • Hcy
    • Reaction
    • Include
    • Methionine
  • dna methylation
    • Dna
    • Methylation
    • Rna
    • Cpg
    • Protein
    • Methionine
    • Human
    • Process
    • Diazomethane
    • Metals
    • Methanogenesis
    • Used
  • dna methyltransferase
    • Methylation
    • Cpg
    • Methionine
    • Protein
    • Rna
    • Diazomethane
    • Metals
    • Methanogenesis
    • Used
    • Enzyme
    • Expression
    • Gene
  • organic chemistry
    • Biology
    • Used
    • Methionine
    • Group
    • Arsenic
    • Commonly
    • Diazomethane
    • Metals
    • Methanogenesis
    • Also
    • Biological
    • Dna
  • methyl triflate
    • Group
    • Groups
    • Include
    • Methionine
    • Methylated
    • Alkylation
    • Enzyme
    • Form
    • Hcy
    • Method
    • Methylating
    • Reagents
  • magic methyl
    • Group
    • Groups
    • Include
    • Methionine
    • Methylated
    • Alkylation
    • Enzyme
    • Form
    • Hcy
    • Method
    • Methylating
    • Reagents
  • in chemistry
    • Biology
    • Used
    • Methionine
    • Group
    • Arsenic
    • Commonly
    • Diazomethane
    • Metals
    • Methanogenesis
    • Also
    • Biological
    • Dna

Connections between topic areas Semantic bridges

For Methylation, one of the stronger structural bridges in this analysis connects Methylation with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Methylation — Overview · splits 70 ⟂ 54
Methylation — In chemistry · splits 91 ⟂ 33
Methylation — In biology · splits 101 ⟂ 23
Methylation — Organic chemistry topics · splits 117 ⟂ 7
Methylation — Biology topics · splits 118 ⟂ 6

Map overview Semantic statistics

Methylation

Nodes124
Edges123
Triples79
Avg. degree1.98
Density0.016129
Components1

Source & methodology

TTTA analyzes the structure around Methylation to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Science, In biology & In chemistry, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Methylation · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.