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Myc: Interactions, Function & Overview
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc.
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Myc topic overview
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around Myc.
Related topics
116
Source areas
10
Connected nodes
127
Extracted relationships
102
Related term clusters
30
Bridge connections
127
What this topic covers Research coverage
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Interactions · 37 topics
Overview · 23 topics
Function · 13 topics
Myc-nick · 10 topics
Clinical significance · 9 topics
Structure · 6 topics
Animal models · 5 topics
MYC rearrangements · 5 topics
Discovery · 4 topics
Relationship to stem cells · 4 topics
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Alt. symbols
c-Myc, v-myc
Domains
InterPro
HGNC
7553
Locus
Chr. 8 q24.21
NCBI gene
4609
OMIM
190080
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A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.
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Advanced semantic analysis
How Myc connects Entity context
Entity context groups extracted connections by relationship type. Counts show recurrence in the analyzed source; the examples are research signals, not claims about importance.
The extracted context around Myc shows recurring relationship patterns in the source. For example, Myc → AKT, Also, AMPK, Burkitt, Classical, CML, CR, Cre-Loxp, Drosophila, Haplo-insufficient, IgM, In Drosophila Myc, John, Later, Less TOR, One, S6K, Sedivy, Targeting Myc Another extracted example is Myc → AICDA, Although AICDA, B-cell, BCL2, BCL6, CSR, DLBCL/HGBCL, DLBCLs, Double, HGBCL, IG, MYC-R, NHL, Non-Hodgkin Lymphoma, Patients, SHM. Use these groups to spot repeated connection types before inspecting the individual relationships.
Relationships are represented as Subject → Predicate → Object triples. Confidence describes extraction strength, not the real-world importance of a relationship; lower-confidence rows may be contextual rather than explicit.
TTTA extracted 102 structured relationships around Myc. Examples in this analysis include Myc → Alt. symbols → c-Myc, v-myc and Myc → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.
Subject
Predicate
Object
Confidence
Src
Myc
Alt. symbols
c-Myc, v-myc
1.00
infobox
Myc
Domains
InterPro
1.00
infobox
Myc
HGNC
7553
1.00
infobox
Myc
Locus
Chr. 8 q24.21
1.00
infobox
Myc
NCBI gene
4609
1.00
infobox
Myc
OMIM
190080
1.00
infobox
Myc
RefSeq
NM_001354870.1
1.00
infobox
Myc
Search for
Search forStructuresSwiss-modelDomainsInterPro
1.00
infobox
Myc
Structures
Swiss-model
1.00
infobox
Myc
Symbol
MYC
1.00
infobox
Myc
UniProt
P01106
1.00
infobox
Myc
Wikidata
Q20969939
1.00
infobox
Myc
causes
tumorigenesis
0.90
text
Myc
is a
family of regulator genes and proto-oncogenes that code for transcription factors
0.90
text
No triples extracted yet.
Related concept clusters Related term clusters
Related term clusters group terms that sit near one another in the extracted graph. They are useful for discovering adjacent language and context, but proximity does not by itself imply a factual relationship.
The concept neighborhoods around Myc bring nearby vocabulary together. In this analysis, examples include Expression, Cells and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
stem cell
Differentiation
Proliferation
Stem
Role
Used
Cells
Myc
Via
Cancer
Function
Rearrangements
Drugs
somatic cells
Stem
Expression
Myc
One
Differentiation
Gene
Models
Protein
Study
Factors
Myc-nick
Role
induced pluripotent stem cells
Stem
Differentiation
Expression
Myc
One
Gene
Models
Protein
Study
Factors
Myc-nick
Role
ectopic expression
Genes
Myc
Cells
Binding
Cancer
Many
Study
Differentiation
Human
Transcription
Stem
Gene
myc rearrangements
Expression
Cells
Gene
C-myc
Cancer
Myc-r
Lymphoma
Also
Cell
Including
Protein
Stem
relationship to stem cells
Stem
Differentiation
Expression
Myc
One
Gene
Models
Protein
Study
Factors
Myc-nick
Role
Myc
Expression
Cells
Gene
C-myc
Cancer
Also
Cell
Including
Protein
Factors
Proteins
Transcription
myc
Expression
Cells
Gene
C-myc
Cancer
Also
Cell
Including
Protein
Factors
Proteins
Transcription
Connections between topic areas Semantic bridges
Semantic bridges connect parts of the graph that would otherwise be more separate. A bridge is a structural signal in this analysis, not a claim that the two topic areas are equivalent.
For Myc, one of the stronger structural bridges in this analysis connects Myc with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.
Myc
Nodes128
Edges127
Triples102
Avg. degree1.98
Density0.015625
Components1
Source & methodology
TTTA analyzes the structure around Myc to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Myc · EN edition · Analysis: TopicsToTalkAbout
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