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PPP1CA: Measurement, Interactions & Function

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme that in humans is encoded by the PPP1CA gene.

Language: English [EN]
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PPP1CA topic overview

The analysis highlights Measurement, Interactions and Function as prominent areas in the source structure around PPP1CA.

Related topics
18
Source areas
3
Connected nodes
21
Extracted relationships
125
Concept neighborhoods
8
Bridge connections
21

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 15 topics
Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.1.3.16
Aliases
PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A, protein phosphatase 1 catalytic subunit alpha
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM
Band
11q13.2 · 19|19 A
Bgee
granulocyte · mucosa of transverse colon · monocyte · spleen · thymus
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PPP1CA connects Entity context

The extracted context around PPP1CA shows recurring relationship patterns in the source. For example, PPP1CA → beta-catenin destruction complex disassembly, branching morphogenesis of an epithelial tube, cadherin binding involved in cell-cell adhesion, carbohydrate metabolic process, cell cycle, cell division, cell-cell adhesion, circadian regulation of gene expression, cytoplasm, cytosol, dendritic spine, dephosphorylation, entrainment of circadian clock by photoperiod, extracellular exosome, glutamatergic synapse, glycogen granule, glycogen metabolic process, hydrolase activity, lung development, metal ion binding Another extracted example is PPP1CA → apex of heart, blood, epiblast, granulocyte, human penis, lymph node, mesencephalon, monocyte, mucosa of pharynx, mucosa of transverse colon, neural tube, olfactory bulb, spleen, striatum of neuraxis, tail of embryo, thymus, white adipose tissue, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

PPP1CA

Top relations

Gene ontology · 50
PPP1CA → beta-catenin destruction complex disassembly, branching morphogenesis of an epithelial tube, cadherin binding involved in cell-cell adhesion, carbohydrate metabolic process, cell cycle, cell division, cell-cell adhesion, circadian regulation of gene expression, cytoplasm, cytosol, dendritic spine, dephosphorylation, entrainment of circadian clock by photoperiod, extracellular exosome, glutamatergic synapse, glycogen granule, glycogen metabolic process, hydrolase activity, lung development, metal ion binding
Bgee · 18
PPP1CA → apex of heart, blood, epiblast, granulocyte, human penis, lymph node, mesencephalon, monocyte, mucosa of pharynx, mucosa of transverse colon, neural tube, olfactory bulb, spleen, striatum of neuraxis, tail of embryo, thymus, white adipose tissue, yolk sac
RNA expression pattern · 18
PPP1CA → apex of heart, blood, epiblast, granulocyte, human penis, lymph node, mesencephalon, monocyte, mucosa of pharynx, mucosa of transverse colon, neural tube, olfactory bulb, spleen, striatum of neuraxis, tail of embryo, thymus, white adipose tissue, yolk sac
related to Interactions · 14
PPP1CA → AKAP11, BCL2-like, BCL2L2, BRCA1, C1, CDC5L, Host, KvLQT1, LMTK2, PHACTR3, PPP1R15A, PPP1R8, PPP1R9B, Protein
Band · 2
PPP1CA → 11q13.2, 19|19 A
Chr. · 2
PPP1CA → Chromosome 11 (human), Chromosome 19 (mouse)
End · 2
PPP1CA → 4,245,419 bp, 67,421,183 bp
3.1.3.16 · 1
PPP1CA → ↗
Aliases · 1
PPP1CA → PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A, protein phosphatase 1 catalytic subunit alpha
Available structures · 1
PPP1CA → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene human chr band phosphatase protein chromosome 11 pp1 serine catalytic location function activity end enzyme mouse cell subunit

PPP1CA relationships Subject–Predicate–Object triples

TTTA extracted 125 structured relationships around PPP1CA. Examples in this analysis include PPP1CA → 3.1.3.16 → ↗ and PPP1CA → Aliases → PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A, protein phosphatase 1 catalytic subunit alpha. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PPP1CA3.1.3.161.00infobox
PPP1CAAliasesPPP1CA, PP-1A, PP1A, PP1alpha, PPP1A, protein phosphatase 1 catalytic subunit alpha1.00infobox
PPP1CAAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM1.00infobox
PPP1CABand11q13.21.00infobox
PPP1CABand19|19 A1.00infobox
PPP1CABgeegranulocyte1.00infobox
PPP1CABgeemucosa of transverse colon1.00infobox
PPP1CABgeemonocyte1.00infobox
PPP1CABgeespleen1.00infobox
PPP1CABgeethymus1.00infobox
PPP1CABgeeapex of heart1.00infobox
PPP1CABgeeblood1.00infobox
PPP1CABgeelymph node1.00infobox
PPP1CABgeemucosa of pharynx1.00infobox
PPP1CABgeehuman penis1.00infobox
PPP1CABgeestriatum of neuraxis1.00infobox
PPP1CABgeetail of embryo1.00infobox
PPP1CABgeeyolk sac1.00infobox
PPP1CABgeeneural tube1.00infobox
PPP1CABgeemesencephalon1.00infobox
PPP1CABgeewhite adipose tissue1.00infobox
PPP1CABgeeepiblast1.00infobox
PPP1CABgeeolfactory bulb1.00infobox
PPP1CABioGPSMore reference expression data1.00infobox
PPP1CAChr.Chromosome 11 (human)1.00infobox
PPP1CAChr.Chromosome 19 (mouse)1.00infobox
PPP1CADatabasesNCBI: entry; OMA: entry1.00infobox
PPP1CAEnd67,421,183 bp1.00infobox
PPP1CAEnd4,245,419 bp1.00infobox
PPP1CAEnsemblENSG000001725311.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PPP1CA bring nearby vocabulary together. In this analysis, examples include Protein, Alpha and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PPP1CA
    • Protein
    • Alpha
    • Gene
    • Pathway
    • Search
    • Subunit
    • Activity
    • Cell
    • Function
    • Location
    • Serine
    • Chromosome
  • ppp1ca
    • Protein
    • Alpha
    • Gene
    • Pathway
    • Search
    • Subunit
    • Activity
    • Cell
    • Function
    • Location
    • Serine
    • Chromosome
  • gene
    • Location
    • Chromosome
    • Phosphatase
    • Ppp1ca
    • Bp
    • Chr
    • Human
    • Alpha
    • Mouse
    • Pathway
    • Search
    • Subunit
  • protein phosphatase 1
    • Catalytic
    • Cell
    • Serine
    • Ppp1ca
    • Protein
    • Alpha
    • Cellular
    • Division
    • Encoded
    • Enzyme
    • Gene
    • Glycogen
  • host cell factor c1
    • Protein
    • Cellular
    • Division
    • Glycogen
    • Involved
    • Regulation
    • Threonine
    • Viral
    • Serine
    • Phosphatase
    • Pp1
    • Ppp1ca
  • function
    • Alpha
    • Pathway
    • Search
    • Human
    • Activity
    • Location
    • Chromosome
    • Phosphatase
    • Pp1
    • Ppp1ca
    • Protein
    • Bp
  • enzyme
    • Subunit
    • Phosphatase
    • Ppp1ca
    • Gene
    • Alpha
    • Encoded
    • Pathway
    • Search
    • Activity
    • Function
    • Location
    • Serine
  • protein kinase r
    • Cell
    • Cellular
    • Division
    • Glycogen
    • Involved
    • Regulation
    • Search
    • Threonine
    • Viral
    • Serine
    • Pp1
    • Heart

Connections between topic areas Semantic bridges

For PPP1CA, one of the stronger structural bridges in this analysis connects PPP1CA with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PPP1CAInteractions · splits 6 ⟂ 16
PPP1CAOverview · splits 19 ⟂ 3

Map overview Semantic statistics

PPP1CA

Nodes22
Edges21
Triples125
Avg. degree1.91
Density0.090909
Components1

Source & methodology

TTTA analyzes the structure around PPP1CA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PPP1CA · EN edition · Analysis: TopicsToTalkAbout

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