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PPP1CA

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme that in humans is encoded by the PPP1CA gene.

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3.1.3.16
Aliases
PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A, protein phosphatase 1 catalytic subunit alpha
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM
Band
11q13.2 · 19|19 A
Bgee
granulocyte · mucosa of transverse colon · monocyte · spleen · thymus
BioGPS
More reference expression data

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Map overview Semantic statistics

PPP1CA

Nodes22
Edges21
Triples125
Avg. degree1.91
Density0.090909
Components1

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PPP1CA

Top relations

Gene ontology · 50
PPP1CA → beta-catenin destruction complex disassembly, branching morphogenesis of an epithelial tube, cadherin binding involved in cell-cell adhesion, carbohydrate metabolic process, cell cycle, cell division, cell-cell adhesion, circadian regulation of gene expression, cytoplasm, cytosol, dendritic spine, dephosphorylation, entrainment of circadian clock by photoperiod, extracellular exosome, glutamatergic synapse, glycogen granule, glycogen metabolic process, hydrolase activity, lung development, metal ion binding
Bgee · 18
PPP1CA → apex of heart, blood, epiblast, granulocyte, human penis, lymph node, mesencephalon, monocyte, mucosa of pharynx, mucosa of transverse colon, neural tube, olfactory bulb, spleen, striatum of neuraxis, tail of embryo, thymus, white adipose tissue, yolk sac
RNA expression pattern · 18
PPP1CA → apex of heart, blood, epiblast, granulocyte, human penis, lymph node, mesencephalon, monocyte, mucosa of pharynx, mucosa of transverse colon, neural tube, olfactory bulb, spleen, striatum of neuraxis, tail of embryo, thymus, white adipose tissue, yolk sac
related to Interactions · 14
PPP1CA → AKAP11, BCL2-like, BCL2L2, BRCA1, C1, CDC5L, Host, KvLQT1, LMTK2, PHACTR3, PPP1R15A, PPP1R8, PPP1R9B, Protein
Band · 2
PPP1CA → 11q13.2, 19|19 A
Chr. · 2
PPP1CA → Chromosome 11 (human), Chromosome 19 (mouse)
End · 2
PPP1CA → 4,245,419 bp, 67,421,183 bp
3.1.3.16 · 1
PPP1CA → ↗
Aliases · 1
PPP1CA → PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A, protein phosphatase 1 catalytic subunit alpha
Available structures · 1
PPP1CA → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM

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Important terminology

bp gene human chr band phosphatase protein chromosome 11 pp1 serine catalytic location function activity end enzyme mouse cell subunit

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PPP1CA3.1.3.161.00infobox
PPP1CAAliasesPPP1CA, PP-1A, PP1A, PP1alpha, PPP1A, protein phosphatase 1 catalytic subunit alpha1.00infobox
PPP1CAAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM1.00infobox
PPP1CABand11q13.21.00infobox
PPP1CABand19|19 A1.00infobox
PPP1CABgeegranulocyte1.00infobox
PPP1CABgeemucosa of transverse colon1.00infobox
PPP1CABgeemonocyte1.00infobox
PPP1CABgeespleen1.00infobox
PPP1CABgeethymus1.00infobox
PPP1CABgeeapex of heart1.00infobox
PPP1CABgeeblood1.00infobox
PPP1CABgeelymph node1.00infobox
PPP1CABgeemucosa of pharynx1.00infobox
PPP1CABgeehuman penis1.00infobox
PPP1CABgeestriatum of neuraxis1.00infobox
PPP1CABgeetail of embryo1.00infobox
PPP1CABgeeyolk sac1.00infobox
PPP1CABgeeneural tube1.00infobox
PPP1CABgeemesencephalon1.00infobox
PPP1CABgeewhite adipose tissue1.00infobox
PPP1CABgeeepiblast1.00infobox
PPP1CABgeeolfactory bulb1.00infobox
PPP1CABioGPSMore reference expression data1.00infobox
PPP1CAChr.Chromosome 11 (human)1.00infobox
PPP1CAChr.Chromosome 19 (mouse)1.00infobox
PPP1CADatabasesNCBI: entry; OMA: entry1.00infobox
PPP1CAEnd67,421,183 bp1.00infobox
PPP1CAEnd4,245,419 bp1.00infobox
PPP1CAEnsemblENSG000001725311.00infobox

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