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Programmed cell death

Programmed cell death (PCD), sometimes referred to as cell suicide or cellular suicide, is the death of a cell as a result of events inside of a cell, such as apoptosis or autophagy. PCD is carried out in a biological process, which usually confers advantage during an organism's lifecycle. For example, the differentiation of fingers and toes in a…

History, Types & Role in the development of the nervous system

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Types

Autophagic cell deathCytoplasmicVacuolesOrganellesNuclear
38 related topics

Role in the development of the nervous system

Nervous systemNeural developmentProgenitor cellsCerebral cortexCerebellum
48 related topics

In plant tissue

Cell-wallImmune systemVacuoleArabidopsisVascular plants
24 related topics

Evolutionary origin of mitochondrial apoptosis

ProtistsBacteriaEndosymbiontsLynn MargulisTheory
20 related topics

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Overview

History

Types

Atrophic factors

Role in the development of the nervous system

In plant tissue

In slime molds

Evolutionary origin of mitochondrial apoptosis

DNA damage and apoptosis

Clinical significance

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Programmed cell death

Nodes235
Edges234
Triples105
Avg. degree1.99
Density0.008511
Components1

How this topic connects Entity context

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Programmed cell death

Top relations

related to Peripheral versus central nervous system · 24
Programmed cell death → Apoptotic, Bax, Bax-mediated, Bcl-2-associated, Bdnf, CNS, Different, Expression, Furthermore, In, It, NGF, NT3, PCD, PNS, Programmed, Regardless, Supporting, Therefore, Together
related to Invertebrates and vertebrates · 13
Programmed cell death → Although, Cell, During, Extensive, For, Furthermore, However, In, In Drosophila, It, Learning, PCD, The
related to Nervous system development in its absence · 11
Programmed cell death → APAF1, Bax, Bcl-2, Excess, For, However, Knockout, Manipulation, PCD, Programmed, The
related to In plant tissue · 8
Programmed cell death → APL, Arabidopsis, In, Instead, Martin Bonke, PCD, Programmed, The
related to The neurotrophic theory · 8
Programmed cell death → Cajal, Experiments, Furthermore, It, NGF, Santiago Ramon, The, This
related to Apoptosis · 7
Programmed cell death → Apoptosis, Biochemical, DNA, It, PCD, There, These
related to Evolutionary origin of mitochondrial apoptosis · 6
Programmed cell death → Biologists, DNA, It, Lynn Margulis, Some, The
related to Other types · 5
Programmed cell death → Besides, Called, Other, PCD, Wallerian
related to Role in the development of the nervous system · 5
Programmed cell death → During, John Beard, PCD, Since, The

Important terminology Word statistics

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Important terminology

cell apoptosis death pcd cells programmed development system nervous dna autophagy theory factors process also necrosis role mitochondria neurons necroptosis

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
trauma or infectioninstance ofNecrosis is the death of a cell caused by external factors0.80text
occurs in several different formsinstance ofNecrosis is the death of a cell caused by external factors0.80text
viruses or mutationsinstance ofIt is hypothesized that necroptosis can serve as a cell-death backup to apoptosis when the apoptosis signaling is blocked by endogenous or exogenous factors0.80text
DNA damage or UV exposureinstance ofThis is the final molecule needed to trigger cell death.Intrinsic pathwayThe intrinsic pathway is caused by cell damage0.80text
cancerinstance ofThis killing of the cells may be essential as it prevents cellular overgrowth which can result in disease0.80text
developmentinstance ofand excess or damaged organelles.Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with physiological as well as pathological p…0.80text
differentiationinstance ofand excess or damaged organelles.Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with physiological as well as pathological p…0.80text
neurodegenerative diseasesinstance ofand excess or damaged organelles.Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with physiological as well as pathological p…0.80text
stressinstance ofand excess or damaged organelles.Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with physiological as well as pathological p…0.80text
infectioninstance ofand excess or damaged organelles.Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with physiological as well as pathological p…0.80text
cancerinstance ofand excess or damaged organelles.Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with physiological as well as pathological p…0.80text
DNA damage or UV exposureinstance ofIntrinsic pathwayThe intrinsic pathway is caused by cell damage0.80text

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