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The mechanistic target of rapamycin (mTOR), also known as mammalian target of rapamycin, is a serine-threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. It belongs to the phosphatidylinositol 3-kinase-related kinase (PIKK) family and is evolutionarily…
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Explore the main themes, entities and connections around MTOR. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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rapamycin protein activity signaling mtorc1 autophagy activation mtorc2 complex target growth also kinase tor cells cell including ad insulin studies
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MTOR | 2.7.10.2 | ↗ | 1.00 | infobox |
| MTOR | 2.7.11.1 | ↗ | 1.00 | infobox |
| MTOR | Aliases | MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS, mechanistic target of rapamycin, mechanistic target of rapamycin kinase | 1.00 | infobox |
| MTOR | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JT6, 1AUE, 1FAP, 1NSG, 2FAP, 2GAQ, 2NPU, 2RSE, 3FAP, 4DRH, 4DRI, 4DRJ, 4FAP, 4JSN, 4JSP, 4JSV, 4JSX, 4JT5,… | 1.00 | infobox |
| MTOR | Band | 1p36.22 | 1.00 | infobox |
| MTOR | Band | 4 E2|4 78.76 cM | 1.00 | infobox |
| MTOR | Bgee | gonad | 1.00 | infobox |
| MTOR | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| MTOR | Bgee | left testis | 1.00 | infobox |
| MTOR | Bgee | right testis | 1.00 | infobox |
| MTOR | Bgee | gastrocnemius muscle | 1.00 | infobox |
| MTOR | Bgee | right frontal lobe | 1.00 | infobox |
| MTOR | Bgee | muscle of thigh | 1.00 | infobox |
| MTOR | Bgee | testicle | 1.00 | infobox |
| MTOR | Bgee | ventricular zone | 1.00 | infobox |
| MTOR | Bgee | apex of heart | 1.00 | infobox |
| MTOR | Bgee | spermatid | 1.00 | infobox |
| MTOR | Bgee | spermatocyte | 1.00 | infobox |
| MTOR | Bgee | right kidney | 1.00 | infobox |
| MTOR | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| MTOR | Bgee | superior frontal gyrus | 1.00 | infobox |
| MTOR | Bgee | genital tubercle | 1.00 | infobox |
| MTOR | Bgee | primary visual cortex | 1.00 | infobox |
| MTOR | Bgee | neural layer of retina | 1.00 | infobox |
| MTOR | BioGPS | More reference expression data | 1.00 | infobox |
| MTOR | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| MTOR | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| MTOR | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MTOR | End | 11,262,551 bp | 1.00 | infobox |
| MTOR | End | 148,642,140 bp | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.