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Atg1

AuTophaGy related 1 (Atg1) is a 101.7kDa serine/threonine kinase in S.cerevisiae, encoded by the gene ATG1. It is essential for the initial building of the autophagosome and Cvt vesicles. In a non-kinase role it is - through complex formation with Atg13 and Atg17 - directly controlled by the TOR kinase, a sensor for nutrient availability.

Structure, Homologues & Function

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Structure

S. cerevisiaeN-terminusC-terminus
3 related topics

Homologues

HomologuesULK1ULK2
3 related topics

Function

EukaryotesPhosphorylation
2 related topics

Regulation

Cell deathProtein kinase A
2 related topics

Key facts & relationships

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Alt. symbols
APG1; AUT3; CVT10
Chromosome
VII: 0.16 - 0.16 Mb
Domains
InterPro
EC number
2.7.11.1
Entrez
852695
Organism
S. cerevisiae S288c

Topics to explore

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Overview

Introduction

Structure

Function

Interaction partners

Regulation

Homologues

Advanced semantic analysis

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Map overview Semantic statistics

Atg1

Nodes24
Edges23
Triples68
Avg. degree1.92
Density0.083333
Components1

How this topic connects Entity context

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Atg1

Top relations

related to Regulation · 19
Atg1 → At, Atg, Atg13, Atg18, Atg8, In, It, PAS, PKA, The, These, This, TOR, Tor1, Tor2, TORC1, TORC2, Under, Upon
related to Interaction partners · 8
Atg1 → Atg, Atg11, Atg13, Atg17, Based, Cvt, Of, The
related to Structure · 8
Atg1 → At, C-terminus, Cvt, N-terminus, The, The Atg1, Until, VII
related to Introduction · 6
Atg1 → Atg, Cvt, Most Atg, PAS, The, To
related to Drosophila melanogaster · 5
Atg1 → Additionally, Atg13, In, The Atg1, TOR
related to Vertebrates · 3
Atg1 → There, ULK1, ULK2
related to Caenorhabditis elegans · 2
Atg1 → The, Unc-51
related to Function · 2
Atg1 → Atg, PAS
related to Homologues · 2
Atg1 → Recent, There
Alt. symbols · 1
Atg1 → APG1; AUT3; CVT10

Important terminology Word statistics

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Important terminology

autophagy atg13 kinase complex cvt nutrient proteins atg functions pas formation cerevisiae function starvation also yeast serine atg17 tor regulation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Atg1Alt. symbolsAPG1; AUT3; CVT101.00infobox
Atg1ChromosomeVII: 0.16 - 0.16 Mb1.00infobox
Atg1DomainsInterPro1.00infobox
Atg1EC number2.7.11.11.00infobox
Atg1Entrez8526951.00infobox
Atg1OrganismS. cerevisiae S288c1.00infobox
Atg1OrthologsNCBI: entry; OMA: entry1.00infobox
Atg1RefSeq (mRNA)NM_0011810451.00infobox
Atg1RefSeq (Prot)NP_0113351.00infobox
Atg1Search forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Atg1StructuresSwiss-model1.00infobox
Atg1SymbolATG11.00infobox
Atg1UniProtP531041.00infobox

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    Min side: 3
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