Autophagy protein 5

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Explore the main themes, entities and connections around Autophagy protein 5. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Clinical Significance

Polymorphisms Behçet's disease Lupus erythematosus Lupus nephritis Parkinson's disease

14 related topics

Function

ATG10 Staurosporine Calpain-1 Calpain-2 Bcl-xL

12 related topics

Regulation

P73 P53 P300 acetylase Acetylate C-ABL tyrosine kinase

9 related topics

Overview

Protein Gene Chromosome 6 Ubi Autophagic cell death

13 related topics

Key facts & relationships

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Aliases: ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5, autophagy related 5, SCAR25
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GDK, 4GDL, 4NAW, 4TQ0, 4TQ1, 5D7G
Band: 6q21 · 10 B2|10 23.24 cM
Bgee: gonad · mucosa of colon · mucosa of sigmoid colon · Achilles tendon · jejunal mucosa
BioGPS: More reference expression data
Chr.: Chromosome 6 (human) · Chromosome 10 (mouse)

Topics to explore

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Overview

Protein
Gene
Chromosome 6
Ubi Ubiquitin
Autophagic cell death Programmed cell death
ATG7
ATG12
ATG16L1
LC3-I MAP1LC3B
PE Phosphatidylethanolamine
Mitochondria Mitochondrion
DNA damage DNA repair
Survivin

Structure

Alpha-helix Alpha helix

Regulation

P73
P53
P300 acetylase P300 (protein)
Acetylate Acetylation
C-ABL tyrosine kinase ABL (gene)
Programmed Cell Death Protein 4 PDCD4
RNA-helicase EIF4A EIF4A helicase
MAPK/ERK kinase kinase 4 MAP kinase kinase kinase
P38 MAPK P38 mitogen-activated protein kinases

Function

Clinical Significance

Polymorphisms Genetic polymorphism
Behçet's disease
Lupus erythematosus
Lupus nephritis
Parkinson's disease
Asthma
Prostate Prostate cancer
Gastrointestinal Gastrointestinal cancer
Colorectal Colorectal cancer
Melanoma
Tumorigenesis Carcinogenesis
M. tuberculosis Mycobacterium tuberculosis
PMN PMN cell
Β-Catenin Beta-catenin

Advanced semantic analysis

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Map overview Semantic statistics

Nodes55

Edges54

Triples108

Avg. degree1.96

Density0.036364

Components1

How this topic connects Entity context

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Autophagy protein 5

Top relations

Gene ontology · 45

Autophagy protein 5 → aggrephagy, antigen processing and presentation of endogenous antigen, apoptotic process, Atg12-Atg5-Atg16 complex, Atg8 ligase activity, autophagosome, autophagosome assembly, autophagy, autophagy of mitochondrion, autophagy of nucleus, axoneme, blood vessel remodeling, C-terminal protein lipidation, cellular homeostasis, cellular response to nitrogen starvation, cellular response to nitrosative stress, cellular response to starvation, cytoplasm, cytosol, heart contraction

Bgee · 20

Autophagy protein 5 → Achilles tendon, endothelial cell, epithelium of stomach, facial motor nucleus, gonad, islet of Langerhans, jejunal mucosa, lacrimal gland, left lobe of liver, mucosa of colon, mucosa of sigmoid colon, oocyte, primary oocyte, rectum, Rostral migratory stream, secondary oocyte, seminal vesicula, testicle, transitional epithelium of urinary bladder, zygote

RNA expression pattern · 20

Band · 2

Autophagy protein 5 → 10 B2|10 23.24 cM, 6q21

Chr. · 2

Autophagy protein 5 → Chromosome 10 (mouse), Chromosome 6 (human)

End · 2

Autophagy protein 5 → 106,325,791 bp, 44,240,287 bp

Aliases · 1

Autophagy protein 5 → ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5, autophagy related 5, SCAR25

Available structures · 1

Autophagy protein 5 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GDK, 4GDL, 4NAW, 4TQ0, 4TQ1, 5D7G

BioGPS · 1

Autophagy protein 5 → More reference expression data

Databases · 1

Autophagy protein 5 → NCBI: entry; OMA: entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

atg5 protein autophagy gene complex cell chromosome bp human chr band also via nucleus location atg12 function dna damage autophagic

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Autophagy protein 5	Aliases	ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5, autophagy related 5, SCAR25	1.00	infobox
Autophagy protein 5	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GDK, 4GDL, 4NAW, 4TQ0, 4TQ1, 5D7G	1.00	infobox
Autophagy protein 5	Band	6q21	1.00	infobox
Autophagy protein 5	Band	10 B2\|10 23.24 cM	1.00	infobox
Autophagy protein 5	Bgee	gonad	1.00	infobox
Autophagy protein 5	Bgee	mucosa of colon	1.00	infobox
Autophagy protein 5	Bgee	mucosa of sigmoid colon	1.00	infobox
Autophagy protein 5	Bgee	Achilles tendon	1.00	infobox
Autophagy protein 5	Bgee	jejunal mucosa	1.00	infobox
Autophagy protein 5	Bgee	endothelial cell	1.00	infobox
Autophagy protein 5	Bgee	oocyte	1.00	infobox
Autophagy protein 5	Bgee	rectum	1.00	infobox
Autophagy protein 5	Bgee	islet of Langerhans	1.00	infobox
Autophagy protein 5	Bgee	testicle	1.00	infobox
Autophagy protein 5	Bgee	primary oocyte	1.00	infobox
Autophagy protein 5	Bgee	secondary oocyte	1.00	infobox
Autophagy protein 5	Bgee	zygote	1.00	infobox
Autophagy protein 5	Bgee	facial motor nucleus	1.00	infobox
Autophagy protein 5	Bgee	lacrimal gland	1.00	infobox
Autophagy protein 5	Bgee	epithelium of stomach	1.00	infobox
Autophagy protein 5	Bgee	left lobe of liver	1.00	infobox
Autophagy protein 5	Bgee	Rostral migratory stream	1.00	infobox
Autophagy protein 5	Bgee	seminal vesicula	1.00	infobox
Autophagy protein 5	Bgee	transitional epithelium of urinary bladder	1.00	infobox
Autophagy protein 5	BioGPS	More reference expression data	1.00	infobox
Autophagy protein 5	Chr.	Chromosome 6 (human)	1.00	infobox
Autophagy protein 5	Chr.	Chromosome 10 (mouse)	1.00	infobox
Autophagy protein 5	Databases	NCBI: entry; OMA: entry	1.00	infobox
Autophagy protein 5	End	106,325,791 bp	1.00	infobox
Autophagy protein 5	End	44,240,287 bp	1.00	infobox

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