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XPB (xeroderma pigmentosum type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex.
The analysis highlights Art, Interactions and Function as prominent areas in the source structure around XPB.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around XPB shows recurring relationship patterns in the source. For example, XPB → 3'-5' DNA helicase activity, 7-methylguanosine mRNA capping, apoptotic process, ATP binding, ATP-dependent activity, acting on DNA, ATPase activity, cellular response to DNA damage stimulus, damaged DNA binding, DNA binding, DNA helicase activity, DNA repair, DNA topological change, DNA translocase activity, embryonic organ development, global genome nucleotide-excision repair, hair cell differentiation, helicase activity, hydrolase activity, nucleoplasm, nucleotide binding Another extracted example is XPB → anterior pituitary, body of uterus, canal of the cervix, endothelial cell of lymphatic vessel, epiblast, ganglionic eminence, gastric mucosa, gonad, granulocyte, lumbar spinal ganglion, medullary collecting duct, renal corpuscle, right hemisphere of cerebellum, right uterine tube, spermatid, sural nerve, tail of embryo, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp dna chr human band gene helicase tfiih chromosome ercc3 transcription xeroderma pigmentosum complex factor location function repair mouse protein
TTTA extracted 169 structured relationships around XPB. Examples in this analysis include XPB → 5.6.2.4 → ↗ and XPB → Aliases → ERCC3, excision repair cross-complementation group 3, BTF2, GTF2H, RAD25, TFIIH, XPB, TTD2, ERCC excision repair 3, TFIIH core complex helicase subunit, Ssl2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| XPB | 5.6.2.4 | ↗ | 1.00 | infobox |
| XPB | Aliases | ERCC3, excision repair cross-complementation group 3, BTF2, GTF2H, RAD25, TFIIH, XPB, TTD2, ERCC excision repair 3, TFIIH core complex helicase subunit, Ssl2 | 1.00 | infobox |
| XPB | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ERN, 5IY9, 5IVW, 5IY7, 5IY8, 5IY6 | 1.00 | infobox |
| XPB | Band | 2q14.3 | 1.00 | infobox |
| XPB | Band | 18|18 B1 | 1.00 | infobox |
| XPB | Bgee | sural nerve | 1.00 | infobox |
| XPB | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| XPB | Bgee | right uterine tube | 1.00 | infobox |
| XPB | Bgee | gastric mucosa | 1.00 | infobox |
| XPB | Bgee | gonad | 1.00 | infobox |
| XPB | Bgee | granulocyte | 1.00 | infobox |
| XPB | Bgee | ganglionic eminence | 1.00 | infobox |
| XPB | Bgee | body of uterus | 1.00 | infobox |
| XPB | Bgee | anterior pituitary | 1.00 | infobox |
| XPB | Bgee | canal of the cervix | 1.00 | infobox |
| XPB | Bgee | spermatid | 1.00 | infobox |
| XPB | Bgee | renal corpuscle | 1.00 | infobox |
| XPB | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| XPB | Bgee | ventricular zone | 1.00 | infobox |
| XPB | Bgee | epiblast | 1.00 | infobox |
| XPB | Bgee | tail of embryo | 1.00 | infobox |
| XPB | Bgee | medullary collecting duct | 1.00 | infobox |
| XPB | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| XPB | Bgee | yolk sac | 1.00 | infobox |
| XPB | BioGPS | More reference expression data | 1.00 | infobox |
| XPB | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| XPB | Chr. | Chromosome 18 (mouse) | 1.00 | infobox |
| XPB | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| XPB | End | 127,294,166 bp | 1.00 | infobox |
| XPB | End | 32,403,204 bp | 1.00 | infobox |
The concept neighborhoods around XPB bring nearby vocabulary together. In this analysis, examples include Ercc3, Helicase and Tfiih. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For XPB, one of the stronger structural bridges in this analysis connects XPB with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around XPB to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Interactions & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — XPB · EN edition · Analysis: TopicsToTalkAbout