Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

KAT5: Interactions, Function & Clinical relevance

Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene. It is also commonly identified as TIP60.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

KAT5 topic overview

The analysis highlights Interactions, Function and Clinical relevance as prominent areas in the source structure around KAT5.

Related topics
41
Source areas
6
Connected nodes
47
Extracted relationships
159
Concept neighborhoods
20
Bridge connections
47

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 12 topics
Function · 10 topics
Overview · 8 topics
Clinical relevance · 6 topics
Regulation · 3 topics
Structure · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.1.48
Aliases
KAT5, ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2, lysine acetyltransferase 5, NEDFASB
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EKO, 2OU2, 4QQG
Band
11q13.1 · 19|19 A
Bgee
right uterine tube · right lobe of thyroid gland · body of uterus · gastric mucosa · right hemisphere of cerebellum
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Regulation

Clinical relevance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How KAT5 connects Entity context

The extracted context around KAT5 shows recurring relationship patterns in the source. For example, KAT5 → acetyltransferase activity, acyltransferase activity, androgen receptor binding, androgen receptor signaling pathway, beta-catenin-TCF complex assembly, cellular response to estradiol stimulus, chromatin organization, cytoplasm, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA double-strand break processing, DNA replication, double-strand break repair, double-strand break repair via nonhomologous end joining, H4 histone acetyltransferase activity, histone acetylation, histone acetyltransferase activity, histone acetyltransferase complex, histone binding, histone H4 acetylation, metal ion binding Another extracted example is KAT5 → body of uterus, cerebellar cortex, gastric mucosa, genital tubercle, granulocyte, hand, interventricular septum, left lobe of thyroid gland, left uterine tube, medial vestibular nucleus, muscle layer of sigmoid colon, neural layer of retina, popliteal artery, right hemisphere of cerebellum, right lobe of thyroid gland, right uterine tube, spermatocyte, tibial arteries, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

KAT5

Top relations

Gene ontology · 44
KAT5 → acetyltransferase activity, acyltransferase activity, androgen receptor binding, androgen receptor signaling pathway, beta-catenin-TCF complex assembly, cellular response to estradiol stimulus, chromatin organization, cytoplasm, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA double-strand break processing, DNA replication, double-strand break repair, double-strand break repair via nonhomologous end joining, H4 histone acetyltransferase activity, histone acetylation, histone acetyltransferase activity, histone acetyltransferase complex, histone binding, histone H4 acetylation, metal ion binding
Bgee · 20
KAT5 → body of uterus, cerebellar cortex, gastric mucosa, genital tubercle, granulocyte, hand, interventricular septum, left lobe of thyroid gland, left uterine tube, medial vestibular nucleus, muscle layer of sigmoid colon, neural layer of retina, popliteal artery, right hemisphere of cerebellum, right lobe of thyroid gland, right uterine tube, spermatocyte, tibial arteries, ventricular zone, yolk sac
RNA expression pattern · 20
KAT5 → body of uterus, cerebellar cortex, gastric mucosa, genital tubercle, granulocyte, hand, interventricular septum, left lobe of thyroid gland, left uterine tube, medial vestibular nucleus, muscle layer of sigmoid colon, neural layer of retina, popliteal artery, right hemisphere of cerebellum, right lobe of thyroid gland, right uterine tube, spermatocyte, tibial arteries, ventricular zone, yolk sac
related to Structure · 7
KAT5 → CHROMO, CoA, DNA, Excess, MYST, The, The CHROMO
related to External links · 6
KAT5 → Histone, Overview, PDB, PDBe-KB, Q92993, UniProt
related to DNA repair · 5
KAT5 → ATM, DNA, However, Lack, TRRAP
related to Apoptosis · 4
KAT5 → Acetylation, DNA, P53, Therefore
related to Cancer · 4
KAT5 → As, Colon, DNA, Therefore
related to Function · 4
KAT5 → Acetylation, DNA, This, Three
related to Regulation · 4
KAT5 → CDK, G2/M, Phosphorylation, Therefore

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dna histone gene repair transcription protein human bp activity apoptosis cancer chr band proteins acetylation histones chromatin acetyltransferase important chromosome

KAT5 relationships Subject–Predicate–Object triples

TTTA extracted 159 structured relationships around KAT5. Examples in this analysis include KAT5 → 2.3.1.48 → ↗ and KAT5 → Aliases → KAT5, ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2, lysine acetyltransferase 5, NEDFASB. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
KAT52.3.1.481.00infobox
KAT5AliasesKAT5, ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, ZC2HC5, cPLA2, lysine acetyltransferase 5, NEDFASB1.00infobox
KAT5Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EKO, 2OU2, 4QQG1.00infobox
KAT5Band11q13.11.00infobox
KAT5Band19|19 A1.00infobox
KAT5Bgeeright uterine tube1.00infobox
KAT5Bgeeright lobe of thyroid gland1.00infobox
KAT5Bgeebody of uterus1.00infobox
KAT5Bgeegastric mucosa1.00infobox
KAT5Bgeeright hemisphere of cerebellum1.00infobox
KAT5Bgeemuscle layer of sigmoid colon1.00infobox
KAT5Bgeeleft lobe of thyroid gland1.00infobox
KAT5Bgeeleft uterine tube1.00infobox
KAT5Bgeepopliteal artery1.00infobox
KAT5Bgeetibial arteries1.00infobox
KAT5Bgeeneural layer of retina1.00infobox
KAT5Bgeespermatocyte1.00infobox
KAT5Bgeegranulocyte1.00infobox
KAT5Bgeeyolk sac1.00infobox
KAT5Bgeeinterventricular septum1.00infobox
KAT5Bgeegenital tubercle1.00infobox
KAT5Bgeehand1.00infobox
KAT5Bgeeventricular zone1.00infobox
KAT5Bgeemedial vestibular nucleus1.00infobox
KAT5Bgeecerebellar cortex1.00infobox
KAT5BioGPSMore reference expression data1.00infobox
KAT5Chr.Chromosome 11 (human)1.00infobox
KAT5Chr.Chromosome 19 (mouse)1.00infobox
KAT5DatabasesNCBI: entry; OMA: entry1.00infobox
KAT5End65,719,604 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around KAT5 bring nearby vocabulary together. In this analysis, examples include Repair, Ability and Regulation. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • enzyme
    • Function
    • Regulation
    • Gene
    • Encoded
    • Dna
    • Hiv
    • Location
    • Tip60
    • Atm
    • Binding
    • Chromosome
    • Important
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • Histone
    • Human
    • Acetyl
    • Function
    • Band
    • Regulation
    • Activity
    • Transcription
  • histone acetyl transferases
    • Acetylation
    • Encoded
    • Gene
    • Hats
    • Play
    • Acetyl
    • Histone
    • Protein
    • Chromatin
    • Important
    • Function
    • Location
  • chromatin
    • Binding
    • Important
    • Histone
    • Transcription
    • Hats
    • Play
    • Repair
    • Dna
    • Function
    • Location
    • Ability
    • Band
  • histone
    • Encoded
    • Gene
    • Hats
    • Play
    • Acetyl
    • Protein
    • Chromatin
    • Important
    • Transcription
    • Repair
    • Function
    • Location
  • dna repair
    • Repair
    • Protein
    • Apoptosis
    • Kat5
    • Binding
    • Transcription
    • Location
    • Tip60
    • Ability
    • P53
    • Regulation
    • Function
  • apoptosis
    • Dna
    • Repair
    • Transcription
    • Play
    • Function
    • Hiv
    • Location
    • Tip60
    • Ability
    • Chromosome
    • Enzyme
    • Important
  • acetyl coa
    • Acetylation
    • Gene
    • Histone
    • Encoded
    • Hats
    • Protein
    • Function
    • Location
    • Acetyltransferase
    • Band
    • Binding
    • Chromatin

Connections between topic areas Semantic bridges

For KAT5, one of the stronger structural bridges in this analysis connects KAT5 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
KAT5Interactions · splits 35 ⟂ 13
KAT5Function · splits 37 ⟂ 11
KAT5Overview · splits 39 ⟂ 9
KAT5Clinical relevance · splits 41 ⟂ 7
KAT5Regulation · splits 44 ⟂ 4
KAT5Structure · splits 45 ⟂ 3

Map overview Semantic statistics

KAT5

Nodes48
Edges47
Triples159
Avg. degree1.96
Density0.041667
Components1

Source & methodology

TTTA analyzes the structure around KAT5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Clinical relevance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — KAT5 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.