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Pyroptosis is a highly inflammatory form of lytic programmed cell death that occurs most frequently upon infection with intracellular pathogens and forms part of the antimicrobial response. This process promotes the rapid clearance of various bacterial, viral, fungal and protozoan infections by removing intracellular replication niches and enhancing the…
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cell caspase-1 cells inflammasome form also inflammatory death infection activation membrane cytokines gsdmd formation apoptosis inflammation caspases inflammasomes cancer pathway
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Pyroptosis | is a | highly inflammatory form of lytic programmed cell death that occurs most frequently upon infection with intracellular pathogens and forms part of the antimicrobial response | 0.90 | text |
| HMGB-1 | instance of | molecules | 0.80 | text |
| ATP | instance of | molecules | 0.80 | text |
| DNA | instance of | molecules | 0.80 | text |
| out of the cell | instance of | molecules | 0.80 | text |
| TLRs | instance of | non-inflammasome-forming PRRs | 0.80 | text |
| NOD1 | instance of | non-inflammasome-forming PRRs | 0.80 | text |
| NOD2 also play important roles in pyroptosis | instance of | non-inflammasome-forming PRRs | 0.80 | text |
| IFN α/β | instance of | These receptors upregulate expression of inflammatory cytokines | 0.80 | text |
| tumour necrosis factor | instance of | These receptors upregulate expression of inflammatory cytokines | 0.80 | text |
| Pyroptosis | related to Cancer | Principally | 0.60 | section |
| Pyroptosis | related to Cancer | DAMPs | 0.60 | section |
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