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Knockout mouse

A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA. They are important animal models for studying the role of genes which have been sequenced but whose functions have not been…

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Overview

Use

Strains

Procedure

Limitations

Advanced semantic analysis

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Map overview Semantic statistics

Knockout mouse

Nodes60
Edges59
Triples10
Avg. degree1.97
Density0.033333
Components1

How this topic connects Entity context

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Knockout mouse

Top relations

related to Strains · 6
Knockout mouse → For, Humans, Li-Fraumeni, Many, Other, There
see also · 4
Knockout mouse → Chimera, Knockout Mouse ConsortiumInternational Mouse, Phenotyping ConsortiumKnockout, Work

Important terminology Word statistics

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Important terminology

gene knockout mice mouse cells stem knocked-out physiology dna humans example also p53 neomycin different new sequence original genes used

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Knockout mouserelated to StrainsThere0.60section
Knockout mouserelated to StrainsMany0.60section
Knockout mouserelated to StrainsFor0.60section
Knockout mouserelated to StrainsHumans0.60section
Knockout mouserelated to StrainsLi-Fraumeni0.60section
Knockout mouserelated to StrainsOther0.60section
Knockout mousesee alsoChimera0.60section
Knockout mousesee alsoWork0.60section
Knockout mousesee alsoKnockout Mouse ConsortiumInternational Mouse0.60section
Knockout mousesee alsoPhenotyping ConsortiumKnockout0.60section

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    Min side: 3
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