Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
FAS-associated death domain protein, also called MORT1, is encoded by the FADD gene on the 11q13.3 region of chromosome 11 in humans.
The analysis highlights Regions, Functions and Roles in cancer as prominent areas in the source structure around FADD. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around FADD shows recurring relationship patterns in the source. For example, FADD → activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, behavioral response to cocaine, caspase binding, CD95 death-inducing signaling complex, cell body, cell surface receptor signaling pathway, cellular response to mechanical stimulus, cytoplasm, cytosol, death effector domain binding, death receptor binding, death-inducing signaling complex, death-inducing signaling complex assembly, defense response to virus, extrinsic apoptotic signaling pathway, extrinsic apoptotic signaling pathway in absence of ligand, extrinsic apoptotic signaling pathway via death domain receptors Another extracted example is FADD → Binding, DD, DEDs, DISC, DNase, DR4, DR5, FADD's DED, Fas, ICAD, Many, Procaspase, The, These, This, TRAIL, Upon. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cell death also protein apoptosis receptor domain cells procaspase role cycle fas complex development nfκb interaction pathway receptors activation nucleus
TTTA extracted 257 structured relationships around FADD. Examples in this analysis include FADD → Aliases → FADD, GIG3, MORT1, Fas associated via death domain, IMD90 and FADD → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3OQ9, 1A1W, 1A1Z, 1E3Y, 1E41, 2GF5, 3EZQ. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| FADD | Aliases | FADD, GIG3, MORT1, Fas associated via death domain, IMD90 | 1.00 | infobox |
| FADD | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3OQ9, 1A1W, 1A1Z, 1E3Y, 1E41, 2GF5, 3EZQ | 1.00 | infobox |
| FADD | Band | 11q13.3 | 1.00 | infobox |
| FADD | Bgee | granulocyte | 1.00 | infobox |
| FADD | Bgee | tendon of biceps brachii | 1.00 | infobox |
| FADD | Bgee | stromal cell of endometrium | 1.00 | infobox |
| FADD | Bgee | mucosa of transverse colon | 1.00 | infobox |
| FADD | Bgee | blood | 1.00 | infobox |
| FADD | Bgee | parotid gland | 1.00 | infobox |
| FADD | Bgee | right adrenal gland | 1.00 | infobox |
| FADD | Bgee | right adrenal cortex | 1.00 | infobox |
| FADD | Bgee | left adrenal gland | 1.00 | infobox |
| FADD | Bgee | epithelium of esophagus | 1.00 | infobox |
| FADD | BioGPS | More reference expression data | 1.00 | infobox |
| FADD | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| FADD | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| FADD | End | 70,207,390 bp | 1.00 | infobox |
| FADD | Ensembl | ENSG00000168040 | 1.00 | infobox |
| FADD | Entrez | 8772 | 1.00 | infobox |
| FADD | External IDs | OMIM: 602457; MGI: 109324; GeneCards: FADD | 1.00 | infobox |
| FADD | Gene location (Human) | Gene location (Human)Chr.Chromosome 11 (human)Band11q13.3Start70,203,296 bpEnd70,207,390 bp | 1.00 | infobox |
| FADD | Gene ontology | identical protein binding | 1.00 | infobox |
| FADD | Gene ontology | tumor necrosis factor receptor superfamily binding | 1.00 | infobox |
| FADD | Gene ontology | death effector domain binding | 1.00 | infobox |
| FADD | Gene ontology | caspase binding | 1.00 | infobox |
| FADD | Gene ontology | protein binding | 1.00 | infobox |
| FADD | Gene ontology | protease binding | 1.00 | infobox |
| FADD | Gene ontology | death receptor binding | 1.00 | infobox |
| FADD | Gene ontology | tumor necrosis factor receptor binding | 1.00 | infobox |
| FADD | Gene ontology | receptor serine/threonine kinase binding | 1.00 | infobox |
The concept neighborhoods around FADD bring nearby vocabulary together. In this analysis, examples include Cell, Role and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For FADD, one of the stronger structural bridges in this analysis connects FADD with Functions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around FADD to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Functions & Roles in cancer, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — FADD · EN edition · Analysis: TopicsToTalkAbout