Research any topic before you write.

Find related topics.Discover entities.See connections.Build a topical map.

Tropomyosin receptor kinase A

Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming tyrosine kinase protein, is a protein that in humans is encoded by the NTRK1 gene.

[EN, English, English]

Members, Interactions & Function

Interactive map loads when it comes into view.
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Tropomyosin receptor kinase A. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.10.1
↗
Aliases
NTRK1, MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA, neurotrophic receptor tyrosine kinase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HE7, 1SHC, 1WWA, 1WWW, 2IFG, 4AOJ, 4F0I, 4GT5, 4CRP, 4PMM, 4PMP, 4PMS, 4PMT, 4YNE, 4YPS
Band
1q23.1 · 3 F1|3 38.62 cM
Bgee
spinal ganglia · apex of heart · testicle · gonad · right auricle of heart
BioGPS
More reference expression data

Topics to explore

A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Family members

Role in disease

Regulation

Interactions

Ligands

Role in cancer

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

Tropomyosin receptor kinase A

Nodes69
Edges68
Triples161
Avg. degree1.97
Density0.028986
Components1

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

See the strongest relationship patterns around the current topic before diving into the raw triples.

Tropomyosin receptor kinase A

Top relations

Gene ontology · 96
Tropomyosin receptor kinase A → ageing, ATP binding, axon, axon guidance, axonogenesis involved in innervation, B cell differentiation, behavioral response to formalin induced pain, cell differentiation, cell surface, cellular response to amyloid-beta, cellular response to growth factor stimulus, cellular response to nerve growth factor stimulus, cellular response to nicotine, circadian rhythm, cytoplasm, cytoplasmic vesicle, dendrite, detection of mechanical stimulus involved in sensory perception of pain, detection of temperature stimulus involved in sensory perception of pain, early endosome
Bgee · 19
Tropomyosin receptor kinase A → apex of heart, body of uterus, embryo, ganglion of vagus nerve, glossopharyngeal ganglion, gonad, left uterine tube, left ventricle, lumbar spinal ganglion, muscle layer of sigmoid colon, neural tube, pons, right auricle of heart, spinal ganglia, superior cervical ganglion, superior frontal gyrus, superior ganglion of vagus nerve, testicle, trigeminal ganglion
RNA expression pattern · 19
Tropomyosin receptor kinase A → apex of heart, body of uterus, embryo, ganglion of vagus nerve, glossopharyngeal ganglion, gonad, left uterine tube, left ventricle, lumbar spinal ganglion, muscle layer of sigmoid colon, neural tube, pons, right auricle of heart, spinal ganglia, superior cervical ganglion, superior frontal gyrus, superior ganglion of vagus nerve, testicle, trigeminal ganglion
Band · 2
Tropomyosin receptor kinase A → 1q23.1, 3 F1|3 38.62 cM
Chr. · 2
Tropomyosin receptor kinase A → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
Tropomyosin receptor kinase A → 156,881,850 bp, 87,702,469 bp
2.7.10.1 · 1
Tropomyosin receptor kinase A → ↗
Aliases · 1
Tropomyosin receptor kinase A → NTRK1, MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA, neurotrophic receptor tyrosine kinase 1
Available structures · 1
Tropomyosin receptor kinase A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HE7, 1SHC, 1WWA, 1WWW, 2IFG, 4AOJ, 4F0I, 4GT5, 4CRP, 4PMM, 4PMP, 4PMS, 4PMT, 4YNE, 4YPS
BioGPS · 1
Tropomyosin receptor kinase A → More reference expression data

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

trka gene receptor trk kinase ngf ntrk1 growth trkb human factor tyrosine differentiation bp role nerve cancer trkc neurotrophin binding

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
Tropomyosin receptor kinase A2.7.10.1↗1.00infobox
Tropomyosin receptor kinase AAliasesNTRK1, MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA, neurotrophic receptor tyrosine kinase 11.00infobox
Tropomyosin receptor kinase AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HE7, 1SHC, 1WWA, 1WWW, 2IFG, 4AOJ, 4F0I, 4GT5, 4CRP, 4PMM, 4PMP, 4PMS, 4PMT, 4YNE, 4YPS1.00infobox
Tropomyosin receptor kinase ABand1q23.11.00infobox
Tropomyosin receptor kinase ABand3 F1|3 38.62 cM1.00infobox
Tropomyosin receptor kinase ABgeespinal ganglia1.00infobox
Tropomyosin receptor kinase ABgeeapex of heart1.00infobox
Tropomyosin receptor kinase ABgeetesticle1.00infobox
Tropomyosin receptor kinase ABgeegonad1.00infobox
Tropomyosin receptor kinase ABgeeright auricle of heart1.00infobox
Tropomyosin receptor kinase ABgeeleft uterine tube1.00infobox
Tropomyosin receptor kinase ABgeepons1.00infobox
Tropomyosin receptor kinase ABgeemuscle layer of sigmoid colon1.00infobox
Tropomyosin receptor kinase ABgeeleft ventricle1.00infobox
Tropomyosin receptor kinase ABgeebody of uterus1.00infobox
Tropomyosin receptor kinase ABgeelumbar spinal ganglion1.00infobox
Tropomyosin receptor kinase ABgeesuperior cervical ganglion1.00infobox
Tropomyosin receptor kinase ABgeeneural tube1.00infobox
Tropomyosin receptor kinase ABgeetrigeminal ganglion1.00infobox
Tropomyosin receptor kinase ABgeeglossopharyngeal ganglion1.00infobox
Tropomyosin receptor kinase ABgeeembryo1.00infobox
Tropomyosin receptor kinase ABgeeganglion of vagus nerve1.00infobox
Tropomyosin receptor kinase ABgeesuperior ganglion of vagus nerve1.00infobox
Tropomyosin receptor kinase ABgeesuperior frontal gyrus1.00infobox
Tropomyosin receptor kinase ABioGPSMore reference expression data1.00infobox
Tropomyosin receptor kinase AChr.Chromosome 1 (human)1.00infobox
Tropomyosin receptor kinase AChr.Chromosome 3 (mouse)1.00infobox
Tropomyosin receptor kinase ADatabasesNCBI: entry; OMA: entry1.00infobox
Tropomyosin receptor kinase AEnd156,881,850 bp1.00infobox
Tropomyosin receptor kinase AEnd87,702,469 bp1.00infobox

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.