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AKT2

AKT2, also known as RAC-beta serine/threonine-protein kinase, is an enzyme that in humans is encoded by the AKT2 gene. It influences metabolite storage as part of the insulin signal transduction pathway.

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2.7.11.1
Aliases
AKT2, v-akt murine thymoma viral oncogene homolog 2, HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA, AKT serine/threonine kinase 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GZK, 1GZN, 1GZO, 1MRV, 1MRY, 1O6K, 1O6L, 1P6S, 2JDO, 2JDR, 2UW9, 2X39, 2XH5, 3D0E, 3E87, 3E88, 3E8D
Band
19q13.2 · 7 A3|7 15.94 cM
Bgee
right uterine tube · right hemisphere of cerebellum · right lobe of thyroid gland · left lobe of thyroid gland · left ovary
BioGPS
More reference expression data

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AKT2

Nodes29
Edges28
Triples143
Avg. degree1.93
Density0.068966
Components1

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AKT2

Top relations

Gene ontology · 59
AKT2 → activation of GTPase activity, apoptotic process, ATP binding, carbohydrate metabolic process, carbohydrate transport, cell cortex, cellular response to high light intensity, cellular response to insulin stimulus, cytoplasm, cytosol, early endosome, endosome, fat cell differentiation, glucose metabolic process, glycogen biosynthetic process, glycogen metabolic process, insulin receptor signaling pathway, intracellular anatomical structure, intracellular membrane-bounded organelle, intracellular protein transmembrane transport
Bgee · 19
AKT2 → aortic valve, ascending aorta, body of uterus, canal of the cervix, choroid plexus of fourth ventricle, gastrocnemius muscle, genital tubercle, granulocyte, lactiferous gland, left lobe of thyroid gland, left ovary, lip, muscle of thigh, right hemisphere of cerebellum, right lobe of thyroid gland, right ovary, right uterine tube, tail of embryo, yolk sac
RNA expression pattern · 19
AKT2 → aortic valve, ascending aorta, body of uterus, canal of the cervix, choroid plexus of fourth ventricle, gastrocnemius muscle, genital tubercle, granulocyte, lactiferous gland, left lobe of thyroid gland, left ovary, lip, muscle of thigh, right hemisphere of cerebellum, right lobe of thyroid gland, right ovary, right uterine tube, tail of embryo, yolk sac
related to External links · 8
AKT2 → Human AKT2, Overview, P31751, PDB, PDBe-KB, RAC-beta, UCSC Genome Browser, UniProt
related to Function · 8
AKT2 → AKT, AKT1, In, It, SH2-like, Src, The, This
related to Clinical significance · 3
AKT2 → Mice, Overexpression, The
Band · 2
AKT2 → 19q13.2, 7 A3|7 15.94 cM
Chr. · 2
AKT2 → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
AKT2 → 27,340,251 bp, 40,285,536 bp
related to Interactions · 2
AKT2 → APPL1, SH3RF1

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Important terminology

gene human bp insulin chr band serine kinase pathway chromosome 19 signal transduction location mouse glucose rac-beta oncogene threonine 15

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
AKT22.7.11.11.00infobox
AKT2AliasesAKT2, v-akt murine thymoma viral oncogene homolog 2, HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA, AKT serine/threonine kinase 21.00infobox
AKT2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GZK, 1GZN, 1GZO, 1MRV, 1MRY, 1O6K, 1O6L, 1P6S, 2JDO, 2JDR, 2UW9, 2X39, 2XH5, 3D0E, 3E87, 3E88, 3E8D1.00infobox
AKT2Band19q13.21.00infobox
AKT2Band7 A3|7 15.94 cM1.00infobox
AKT2Bgeeright uterine tube1.00infobox
AKT2Bgeeright hemisphere of cerebellum1.00infobox
AKT2Bgeeright lobe of thyroid gland1.00infobox
AKT2Bgeeleft lobe of thyroid gland1.00infobox
AKT2Bgeeleft ovary1.00infobox
AKT2Bgeeright ovary1.00infobox
AKT2Bgeebody of uterus1.00infobox
AKT2Bgeemuscle of thigh1.00infobox
AKT2Bgeecanal of the cervix1.00infobox
AKT2Bgeegastrocnemius muscle1.00infobox
AKT2Bgeechoroid plexus of fourth ventricle1.00infobox
AKT2Bgeegenital tubercle1.00infobox
AKT2Bgeelip1.00infobox
AKT2Bgeegranulocyte1.00infobox
AKT2Bgeeascending aorta1.00infobox
AKT2Bgeeaortic valve1.00infobox
AKT2Bgeetail of embryo1.00infobox
AKT2Bgeelactiferous gland1.00infobox
AKT2Bgeeyolk sac1.00infobox
AKT2BioGPSMore reference expression data1.00infobox
AKT2Chr.Chromosome 19 (human)1.00infobox
AKT2Chr.Chromosome 7 (mouse)1.00infobox
AKT2DatabasesNCBI: entry; OMA: entry1.00infobox
AKT2End40,285,536 bp1.00infobox
AKT2End27,340,251 bp1.00infobox

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