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AKT2, also known as RAC-beta serine/threonine-protein kinase, is an enzyme that in humans is encoded by the AKT2 gene. It influences metabolite storage as part of the insulin signal transduction pathway.
The analysis highlights Art, Function and Clinical significance as prominent areas in the source structure around AKT2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around AKT2 shows recurring relationship patterns in the source. For example, AKT2 → activation of GTPase activity, apoptotic process, ATP binding, carbohydrate metabolic process, carbohydrate transport, cell cortex, cellular response to high light intensity, cellular response to insulin stimulus, cytoplasm, cytosol, early endosome, endosome, fat cell differentiation, glucose metabolic process, glycogen biosynthetic process, glycogen metabolic process, insulin receptor signaling pathway, intracellular anatomical structure, intracellular membrane-bounded organelle, intracellular protein transmembrane transport Another extracted example is AKT2 → aortic valve, ascending aorta, body of uterus, canal of the cervix, choroid plexus of fourth ventricle, gastrocnemius muscle, genital tubercle, granulocyte, lactiferous gland, left lobe of thyroid gland, left ovary, lip, muscle of thigh, right hemisphere of cerebellum, right lobe of thyroid gland, right ovary, right uterine tube, tail of embryo, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
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gene human bp insulin chr band serine kinase pathway chromosome 19 signal transduction location mouse glucose rac-beta oncogene threonine 15
TTTA extracted 130 structured relationships around AKT2. Examples in this analysis include AKT2 → 2.7.11.1 → ↗ and AKT2 → Aliases → AKT2, v-akt murine thymoma viral oncogene homolog 2, HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA, AKT serine/threonine kinase 2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| AKT2 | 2.7.11.1 | ↗ | 1.00 | infobox |
| AKT2 | Aliases | AKT2, v-akt murine thymoma viral oncogene homolog 2, HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA, AKT serine/threonine kinase 2 | 1.00 | infobox |
| AKT2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GZK, 1GZN, 1GZO, 1MRV, 1MRY, 1O6K, 1O6L, 1P6S, 2JDO, 2JDR, 2UW9, 2X39, 2XH5, 3D0E, 3E87, 3E88, 3E8D | 1.00 | infobox |
| AKT2 | Band | 19q13.2 | 1.00 | infobox |
| AKT2 | Band | 7 A3|7 15.94 cM | 1.00 | infobox |
| AKT2 | Bgee | right uterine tube | 1.00 | infobox |
| AKT2 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| AKT2 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| AKT2 | Bgee | left lobe of thyroid gland | 1.00 | infobox |
| AKT2 | Bgee | left ovary | 1.00 | infobox |
| AKT2 | Bgee | right ovary | 1.00 | infobox |
| AKT2 | Bgee | body of uterus | 1.00 | infobox |
| AKT2 | Bgee | muscle of thigh | 1.00 | infobox |
| AKT2 | Bgee | canal of the cervix | 1.00 | infobox |
| AKT2 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| AKT2 | Bgee | choroid plexus of fourth ventricle | 1.00 | infobox |
| AKT2 | Bgee | genital tubercle | 1.00 | infobox |
| AKT2 | Bgee | lip | 1.00 | infobox |
| AKT2 | Bgee | granulocyte | 1.00 | infobox |
| AKT2 | Bgee | ascending aorta | 1.00 | infobox |
| AKT2 | Bgee | aortic valve | 1.00 | infobox |
| AKT2 | Bgee | tail of embryo | 1.00 | infobox |
| AKT2 | Bgee | lactiferous gland | 1.00 | infobox |
| AKT2 | Bgee | yolk sac | 1.00 | infobox |
| AKT2 | BioGPS | More reference expression data | 1.00 | infobox |
| AKT2 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| AKT2 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| AKT2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| AKT2 | End | 40,285,536 bp | 1.00 | infobox |
| AKT2 | End | 27,340,251 bp | 1.00 | infobox |
The concept neighborhoods around AKT2 bring nearby vocabulary together. In this analysis, examples include Insulin, Gene and Mice. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For AKT2, one of the stronger structural bridges in this analysis connects AKT2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around AKT2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — AKT2 · EN edition · Analysis: TopicsToTalkAbout
