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Peptidyl-prolyl cis-trans isomerase FKBP1A is an enzyme that in humans is encoded by the FKBP1A gene. It is also commonly referred to as FKBP-12 or FKBP12 and is a member of a family of FK506-binding proteins (FKBPs).
The analysis highlights Standards, Function and Interactions as prominent areas in the source structure around FKBP1A.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around FKBP1A shows recurring relationship patterns in the source. For example, FKBP1A → 'de novo' protein folding, activin binding, amyloid fibril formation, axon terminus, calcium channel inhibitor activity, calcium ion transmembrane transport, chaperone-mediated protein folding, cytokine-mediated signaling pathway, cytoplasm, cytoplasmic side of membrane, cytosol, enzyme binding, extracellular exosome, extrinsic component of organelle membrane, FK506 binding, heart morphogenesis, heart trabecula formation, Hsp70 protein binding, intracellular membrane-bounded organelle, isomerase activity Another extracted example is FKBP1A → anterior amygdaloid area, dentate gyrus of hippocampal formation granule cell, endocardial cushion, epithelium of colon, external carotid artery, Gonadal ridge, internal carotid artery, lateral septal nucleus, left lobe of thyroid gland, left uterine tube, monocyte, nucleus accumbens, olfactory tubercle, rectum, right lobe of thyroid gland, right lung, smooth muscle tissue, subiculum, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene bp human chr band protein isomerase chromosome 20 enzyme mouse receptor cis-trans location fk506 encoded intracellular peptidyl-prolyl fkbp-12 fkbp12
TTTA extracted 129 structured relationships around FKBP1A. Examples in this analysis include FKBP1A → 5.2.1.8 → ↗ and FKBP1A → Aliases → FKBP1A, FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE, FK506 binding protein 1A, FKBP prolyl isomerase 1A. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| FKBP1A | 5.2.1.8 | ↗ | 1.00 | infobox |
| FKBP1A | Aliases | FKBP1A, FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE, FK506 binding protein 1A, FKBP prolyl isomerase 1A | 1.00 | infobox |
| FKBP1A | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A7X, 1B6C, 1BKF, 1BL4, 1D6O, 1D7H, 1D7I, 1D7J, 1EYM, 1F40, 1FAP, 1FKB, 1FKD, 1FKF, 1FKG, 1FKH, 1FKI, 1FKJ,… | 1.00 | infobox |
| FKBP1A | Band | 20p13 | 1.00 | infobox |
| FKBP1A | Band | 2|2 G3 | 1.00 | infobox |
| FKBP1A | Bgee | right lung | 1.00 | infobox |
| FKBP1A | Bgee | monocyte | 1.00 | infobox |
| FKBP1A | Bgee | upper lobe of left lung | 1.00 | infobox |
| FKBP1A | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| FKBP1A | Bgee | left lobe of thyroid gland | 1.00 | infobox |
| FKBP1A | Bgee | nucleus accumbens | 1.00 | infobox |
| FKBP1A | Bgee | epithelium of colon | 1.00 | infobox |
| FKBP1A | Bgee | rectum | 1.00 | infobox |
| FKBP1A | Bgee | left uterine tube | 1.00 | infobox |
| FKBP1A | Bgee | smooth muscle tissue | 1.00 | infobox |
| FKBP1A | Bgee | lateral septal nucleus | 1.00 | infobox |
| FKBP1A | Bgee | olfactory tubercle | 1.00 | infobox |
| FKBP1A | Bgee | external carotid artery | 1.00 | infobox |
| FKBP1A | Bgee | internal carotid artery | 1.00 | infobox |
| FKBP1A | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| FKBP1A | Bgee | subiculum | 1.00 | infobox |
| FKBP1A | Bgee | anterior amygdaloid area | 1.00 | infobox |
| FKBP1A | Bgee | endocardial cushion | 1.00 | infobox |
| FKBP1A | Bgee | Gonadal ridge | 1.00 | infobox |
| FKBP1A | BioGPS | More reference expression data | 1.00 | infobox |
| FKBP1A | Chr. | Chromosome 20 (human) | 1.00 | infobox |
| FKBP1A | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| FKBP1A | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| FKBP1A | End | 1,393,164 bp | 1.00 | infobox |
| FKBP1A | End | 151,403,612 bp | 1.00 | infobox |
The concept neighborhoods around FKBP1A bring nearby vocabulary together. In this analysis, examples include Enzyme, Isomerase and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For FKBP1A, one of the stronger structural bridges in this analysis connects FKBP1A with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around FKBP1A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — FKBP1A · EN edition · Analysis: TopicsToTalkAbout