CDC42

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CDC42 topic overview

The analysis highlights Interactions, Role in cancer and Function as prominent areas in the source structure around CDC42.

Related topics: 50
Source areas: 6
Connected nodes: 56
Extracted relationships: 271
Concept neighborhoods: 16
Bridge connections: 56

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 24 topics

Role in cancer · 9 topics

Function · 8 topics

Overview · 3 topics

Structure · 3 topics

Takenouchi-Kosaki syndrome · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.6.5.2: ↗
Aliases: CDC42, CDC42Hs, G25K, TKS, cell division cycle 42
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YDH, 1A4R, 1AJE, 1AM4, 1AN0, 1CEE, 1CF4, 1DOA, 1E0A, 1EES, 1GRN, 1GZS, 1KI1, 1KZ7, 1KZG, 1NF3, 2ASE, 2DFK,…
Band: 1p36.12 · 4 D3|4 69.83 cM
Bgee: monocyte · islet of Langerhans · rectum · ganglionic eminence · gallbladder
BioGPS: More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Role in cancer

Takenouchi-Kosaki syndrome

Takenouchi-Kosaki syndrome Takenouchi-Kosaki syndrome?action=edit&redlink=1
Autosomal-dominant Dominance (genetics)
Thrombocytopenia

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CDC42 connects Entity context

The extracted context around CDC42 shows recurring relationship patterns in the source. For example, CDC42 → actin cytoskeleton organization, actin filament branching, actin filament bundle assembly, actin filament organization, adherens junction organization, apical part of cell, apolipoprotein A-I receptor binding, blood coagulation, canonical Wnt signaling pathway, cardiac conduction system development, Cdc42 protein signal transduction, cell cortex, cell differentiation, cell junction assembly, cell periphery, cell projection, cell projection assembly, cell-cell junction, centrosome, cytoplasm Another extracted example is CDC42 → Aldrich, ARHGAP1, ARHGDIA, BAIAP2, BNIP2, BNIPL, CDC42EP2, CDC42EP3, ERRFI1, GDI1, IQGAP1, IQGAP2, ITSN1, MAP3K10, MAP3K11, PAK1, PAK2, PAK4, PAK7, PARD6A. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 137

CDC42 → actin cytoskeleton organization, actin filament branching, actin filament bundle assembly, actin filament organization, adherens junction organization, apical part of cell, apolipoprotein A-I receptor binding, blood coagulation, canonical Wnt signaling pathway, cardiac conduction system development, Cdc42 protein signal transduction, cell cortex, cell differentiation, cell junction assembly, cell periphery, cell projection, cell projection assembly, cell-cell junction, centrosome, cytoplasm

related to Interactions · 25

CDC42 → Aldrich, ARHGAP1, ARHGDIA, BAIAP2, BNIP2, BNIPL, CDC42EP2, CDC42EP3, ERRFI1, GDI1, IQGAP1, IQGAP2, ITSN1, MAP3K10, MAP3K11, PAK1, PAK2, PAK4, PAK7, PARD6A

Bgee · 20

CDC42 → aortic valve, ascending aorta, dermis, endothelial cell of lymphatic vessel, Epithelium of choroid plexus, epithelium of colon, gallbladder, ganglionic eminence, granulocyte, islet of Langerhans, medullary collecting duct, molar, monocyte, olfactory zone of nasal mucosa, rectum, renal corpuscle, smooth muscle tissue, stroma of bone marrow, ventricular zone, vestibular sensory epithelium

RNA expression pattern · 20

related to Structure · 11

CDC42 → GAPs, GDP, GDP-bound, GEFs, GTP, GTP-binding, GTP-bound, GTPase, Its, P-loop, This

related to Takenouchi-Kosaki syndrome · 9

CDC42 → Alleic, Arg66Gly, Cys81Phe, Glu171Lys, Ile21Thr, Mutations, Ser83Pro, Takenouchi-Kosaki, Tyr64Cys

related to External links · 8

CDC42 → CDC42 Info, Cell Migration GatewayHuman CDC42, GTP-Binding, Medicine Medical Subject Headings, MeSH, National Library, Protein, UCSC Genome Browser

related to Role in cancer · 8

CDC42 → Elevated, G1-S, It, NFkB, Recently, Several, SRF, STAT3

related to Function · 7

CDC42 → Activated Cdc42, GTPase, Human Cdc42, PAK1, PAK2, Rho, Rho GTPases

Band · 2

CDC42 → 1p36.12, 4 D3|4 69.83 cM

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cell cancer cells migration gene endothelial human bp protein chr band division gtpase adhesion signaling integrin chromosome expression location treatment

CDC42 relationships Subject–Predicate–Object triples

TTTA extracted 271 structured relationships around CDC42. Examples in this analysis include CDC42 → 3.6.5.2 → ↗ and CDC42 → Aliases → CDC42, CDC42Hs, G25K, TKS, cell division cycle 42. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
CDC42	3.6.5.2	↗	1.00	infobox
CDC42	Aliases	CDC42, CDC42Hs, G25K, TKS, cell division cycle 42	1.00	infobox
CDC42	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YDH, 1A4R, 1AJE, 1AM4, 1AN0, 1CEE, 1CF4, 1DOA, 1E0A, 1EES, 1GRN, 1GZS, 1KI1, 1KZ7, 1KZG, 1NF3, 2ASE, 2DFK,…	1.00	infobox
CDC42	Band	1p36.12	1.00	infobox
CDC42	Band	4 D3\|4 69.83 cM	1.00	infobox
CDC42	Bgee	monocyte	1.00	infobox
CDC42	Bgee	islet of Langerhans	1.00	infobox
CDC42	Bgee	rectum	1.00	infobox
CDC42	Bgee	ganglionic eminence	1.00	infobox
CDC42	Bgee	gallbladder	1.00	infobox
CDC42	Bgee	epithelium of colon	1.00	infobox
CDC42	Bgee	smooth muscle tissue	1.00	infobox
CDC42	Bgee	olfactory zone of nasal mucosa	1.00	infobox
CDC42	Bgee	granulocyte	1.00	infobox
CDC42	Bgee	ventricular zone	1.00	infobox
CDC42	Bgee	ascending aorta	1.00	infobox
CDC42	Bgee	aortic valve	1.00	infobox
CDC42	Bgee	Epithelium of choroid plexus	1.00	infobox
CDC42	Bgee	endothelial cell of lymphatic vessel	1.00	infobox
CDC42	Bgee	stroma of bone marrow	1.00	infobox
CDC42	Bgee	medullary collecting duct	1.00	infobox
CDC42	Bgee	renal corpuscle	1.00	infobox
CDC42	Bgee	molar	1.00	infobox
CDC42	Bgee	vestibular sensory epithelium	1.00	infobox
CDC42	Bgee	dermis	1.00	infobox
CDC42	BioGPS	More reference expression data	1.00	infobox
CDC42	Chr.	Chromosome 1 (human)	1.00	infobox
CDC42	Chr.	Chromosome 4 (mouse)	1.00	infobox
CDC42	Databases	NCBI: entry; OMA: entry	1.00	infobox
CDC42	End	22,101,360 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CDC42 bring nearby vocabulary together. In this analysis, examples include Cancer, Cell and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

CDC42
- Cancer
- Cell
- Cells
- Migration
- Gene
- Expression
- Syndrome
- Treatment
- Adhesion
- Protein
- Colon
- Cycle
cdc42
- Cancer
- Cell
- Cells
- Migration
- Gene
- Expression
- Syndrome
- Treatment
- Adhesion
- Protein
- Colon
- Cycle
cell cycle
- Activity
- Involved
- Migration
- Chromosome
- Division
- Location
- Bp
- Chr
- Human
- Gene
- Cdc42
- Cycle
cell division
- Cellular
- Migration
- Activity
- Cycle
- Gene
- Division
- Chromosome
- Location
- Signaling
- Bp
- Chr
- Human
cell migration
- Migration
- Division
- Gene
- Cdc42
- Cycle
- Control
- Location
- Signaling
- Human
- Cells
- Mouse
- Rho
cell polarity
- Migration
- Division
- Gene
- Cdc42
- Cycle
- Control
- Location
- Signaling
- Human
- Cancer
- Cellular
- Actin
role in cancer
- Cells
- Cdc42
- Endothelial
- Also
- Membrane
- Cell
- Cdc42-deficient
- Treatment
- Migration
- Colon
- Extracellular
- Signaling
endothelial
- Cells
- Extracellular
- Membrane
- Factor
- Migration
- Integrin
- Β1
- Cdc42-deficient
- Involved
- Mouse
- Process
- Rho

Connections between topic areas Semantic bridges

For CDC42, one of the stronger structural bridges in this analysis connects CDC42 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

CDC42 — Interactions · splits 32 ⟂ 25

CDC42 — Role in cancer · splits 47 ⟂ 10

CDC42 — Function · splits 48 ⟂ 9

CDC42 — Overview · splits 53 ⟂ 4

CDC42 — Structure · splits 53 ⟂ 4

CDC42 — Takenouchi-Kosaki syndrome · splits 53 ⟂ 4

Map overview Semantic statistics

CDC42

Nodes57

Edges56

Triples271

Avg. degree1.96

Density0.035088

Components1

Source & methodology

TTTA analyzes the structure around CDC42 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Role in cancer & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CDC42 · EN edition · Analysis: TopicsToTalkAbout