Insulin-like growth factor 2

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Clinical relevance

Islet Tumors Non-islet hypoglycemic cell tumors Hypoglycemia Doege-Potter syndrome

10 related topics

Gene structure

Gene Chromosome 11p Imprinted genes Homologous region Allele

9 related topics

Function

Gestation IGF-1 receptor IGF-2 receptor Mannose 6-phosphate receptor Progesterone

9 related topics

Interactions

Interact IGFBP3 Transferrin

3 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: insulin-like growth factor 2AL033362Igf-2Igf-IIM6prMprPeg2
Band: 7 F5|7 87.99 cM
Bgee: extraembryonic membrane · yolk sac · genital tubercle · placenta · tail of embryo
BioGPS: n/a
Chr.: Chromosome 7 (human)
Databases: NCBI: entry; OMA: entry

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Overview

Gene structure

Gene
Chromosome 11p Chromosome 11
Imprinted genes Genomic Imprinting
Homologous region Homology (biology)
Allele
CTCF
Expression Gene expression
H19 H19 (gene)
DNA sequences DNA sequence

Function

Gestation
IGF-1 receptor Insulin-like growth factor 1 receptor
IGF-2 receptor Insulin-like growth factor 2 receptor
Mannose 6-phosphate receptor
Progesterone
IGFBP7
Neurogenesis
Fear
PTSD

Clinical relevance

Islet Islets of Langerhans
Tumors Tumor
Non-islet hypoglycemic cell tumors Non islet hypoglycemic cell tumor
Hypoglycemia
Doege-Potter syndrome
Paraneoplastic syndrome
Pleural cavity
Beckwith-Wiedemann syndrome
Preeclampsia
Polychlorinated biphenyls

Interactions

Interact Protein-protein interaction
IGFBP3
Transferrin

Advanced semantic analysis

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Map overview Semantic statistics

Nodes42

Edges41

Triples91

Avg. degree1.95

Density0.047619

Components1

How this topic connects Entity context

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Insulin-like growth factor 2

Top relations

Gene ontology · 49

Insulin-like growth factor 2 → animal organ morphogenesis, carbohydrate metabolic process, collagen-containing extracellular matrix, embryonic placenta development, embryonic placenta morphogenesis, exocrine pancreas development, extracellular region, extracellular space, glucose metabolic process, growth factor activity, hormone activity, in utero embryonic development, insulin receptor binding, insulin receptor signaling pathway via phosphatidylinositol 3-kinase, insulin-like growth factor receptor binding, integrin binding, memory, negative regulation of natural killer cell mediated cytotoxicity, negative regulation of transcription by RNA polymerase II, ossification

Bgee · 10

Insulin-like growth factor 2 → dentate gyrus of hippocampal formation granule cell, extraembryonic membrane, genital tubercle, intra-embryonic coelom, mesencephalon, neural tube, placenta, rhombencephalon, tail of embryo, yolk sac

RNA expression pattern · 10

related to Interactions · 2

Insulin-like growth factor 2 → IGFBP3, Insulin-like

see also · 2

Insulin-like growth factor 2 → II IRES, Insulin-like

Aliases · 1

Insulin-like growth factor 2 → insulin-like growth factor 2AL033362Igf-2Igf-IIM6prMprPeg2

Band · 1

Insulin-like growth factor 2 → 7 F5|7 87.99 cM

BioGPS · 1

Insulin-like growth factor 2 → n/a

Chr. · 1

Insulin-like growth factor 2 → Chromosome 7 (human)

Databases · 1

Insulin-like growth factor 2 → NCBI: entry; OMA: entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

igf-2 growth insulin-like igf2 factor region gene hormone chromosome human insulin preptin expression bp peptide allele ctcf believed major receptor

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Insulin-like growth factor 2	Aliases	insulin-like growth factor 2AL033362Igf-2Igf-IIM6prMprPeg2	1.00	infobox
Insulin-like growth factor 2	Band	7 F5\|7 87.99 cM	1.00	infobox
Insulin-like growth factor 2	Bgee	extraembryonic membrane	1.00	infobox
Insulin-like growth factor 2	Bgee	yolk sac	1.00	infobox
Insulin-like growth factor 2	Bgee	genital tubercle	1.00	infobox
Insulin-like growth factor 2	Bgee	placenta	1.00	infobox
Insulin-like growth factor 2	Bgee	tail of embryo	1.00	infobox
Insulin-like growth factor 2	Bgee	neural tube	1.00	infobox
Insulin-like growth factor 2	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
Insulin-like growth factor 2	Bgee	intra-embryonic coelom	1.00	infobox
Insulin-like growth factor 2	Bgee	rhombencephalon	1.00	infobox
Insulin-like growth factor 2	Bgee	mesencephalon	1.00	infobox
Insulin-like growth factor 2	BioGPS	n/a	1.00	infobox
Insulin-like growth factor 2	Chr.	Chromosome 7 (human)	1.00	infobox
Insulin-like growth factor 2	Databases	NCBI: entry; OMA: entry	1.00	infobox
Insulin-like growth factor 2	End	142,220,553 bp	1.00	infobox
Insulin-like growth factor 2	Ensembl	ENSMUSG00000048583	1.00	infobox
Insulin-like growth factor 2	Entrez	16002	1.00	infobox
Insulin-like growth factor 2	External IDs	GeneCards:	1.00	infobox
Insulin-like growth factor 2	Gene location (Human)	Gene location (Human)Chr.Chromosome 7 (human)Band7 F5\|7 87.99 cMStart142,204,503 bpEnd142,220,553 bp	1.00	infobox
Insulin-like growth factor 2	Gene ontology	hormone activity	1.00	infobox
Insulin-like growth factor 2	Gene ontology	protein serine/threonine kinase activator activity	1.00	infobox
Insulin-like growth factor 2	Gene ontology	protein binding	1.00	infobox
Insulin-like growth factor 2	Gene ontology	growth factor activity	1.00	infobox
Insulin-like growth factor 2	Gene ontology	receptor ligand activity	1.00	infobox
Insulin-like growth factor 2	Gene ontology	insulin receptor binding	1.00	infobox
Insulin-like growth factor 2	Gene ontology	insulin-like growth factor receptor binding	1.00	infobox
Insulin-like growth factor 2	Gene ontology	integrin binding	1.00	infobox
Insulin-like growth factor 2	Gene ontology	extracellular region	1.00	infobox
Insulin-like growth factor 2	Gene ontology	extracellular space	1.00	infobox

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