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Galectin-9

Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9 gene.

Standards, Function & Clinical significance

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Function

25 related topics

Clinical significance

4 related topics

Overview

1 related topics

Key facts & relationships

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Aliases
LGALS9, HUAT, LGALS9A, galectin 9
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EAK, 2EAL, 2YY1, 2ZHK, 2ZHL, 2ZHM, 2ZHN, 3LSD, 3LSE, 3NV1, 3NV2, 3NV3, 3NV4, 3WLU, 3WV6
Band
17q11.2 · 11|11 B5
Bgee
monocyte · granulocyte · mucosa of transverse colon · rectum · gallbladder
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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Overview

Function

Clinical significance

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Map overview Semantic statistics

Galectin-9

Nodes34
Edges33
Triples176
Avg. degree1.94
Density0.058824
Components1

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Galectin-9

Top relations

Gene ontology · 53
Galectin-9 → carbohydrate binding, cellular response to interferon-gamma, chemotaxis, cytoplasm, cytosol, disaccharide binding, enzyme binding, ERK1 and ERK2 cascade, extracellular exosome, extracellular region, extracellular space, female pregnancy, galactose binding, immune system process, inflammatory response, intracellular anatomical structure, maternal process involved in female pregnancy, mature conventional dendritic cell differentiation, natural killer cell tolerance induction, negative regulation of activated T cell proliferation
related to Function · 22
Galectin-9 → AMPK, CD137, CD40, CLEC7A, For, Galectin-8-based, HAVCR2, However, K63, LAMP1, LAMP2, MAP3K7, Mild, SCRAB2, T-cells, TAK1, The, This, TIM-3, TMEM192
Bgee · 19
Galectin-9 → appendix, crypt of lieberkuhn of small intestine, duodenum, epithelium of colon, epithelium of stomach, gallbladder, gastric mucosa, granulocyte, left lobe of liver, lymph node, monocyte, mucosa of transverse colon, mucous cell of stomach, pyloric antrum, pylorus, rectum, seminal vesicula, spleen, thymus
RNA expression pattern · 19
Galectin-9 → appendix, crypt of lieberkuhn of small intestine, duodenum, epithelium of colon, epithelium of stomach, gallbladder, gastric mucosa, granulocyte, left lobe of liver, lymph node, monocyte, mucosa of transverse colon, mucous cell of stomach, pyloric antrum, pylorus, rectum, seminal vesicula, spleen, thymus
related to Clinical significance · 10
Galectin-9 → AML, CLL, HAVCR2, Hodgkin's, MDS, Moreover, T-cell, The, Therefore, This
related to External links · 5
Galectin-9 → O00182, Overview, PDB, PDBe-KB, UniProt
Band · 2
Galectin-9 → 11|11 B5, 17q11.2
Chr. · 2
Galectin-9 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
Galectin-9 → 27,649,560 bp, 78,875,772 bp
Aliases · 1
Galectin-9 → LGALS9, HUAT, LGALS9A, galectin 9

Important terminology Word statistics

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Important terminology

human bp gene chr band tumor ampk chromosome 17 mouse lgals9 lysosomal function expression protein location immune cell intracellular regulation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Galectin-9AliasesLGALS9, HUAT, LGALS9A, galectin 91.00infobox
Galectin-9Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EAK, 2EAL, 2YY1, 2ZHK, 2ZHL, 2ZHM, 2ZHN, 3LSD, 3LSE, 3NV1, 3NV2, 3NV3, 3NV4, 3WLU, 3WV61.00infobox
Galectin-9Band17q11.21.00infobox
Galectin-9Band11|11 B51.00infobox
Galectin-9Bgeemonocyte1.00infobox
Galectin-9Bgeegranulocyte1.00infobox
Galectin-9Bgeemucosa of transverse colon1.00infobox
Galectin-9Bgeerectum1.00infobox
Galectin-9Bgeegallbladder1.00infobox
Galectin-9Bgeespleen1.00infobox
Galectin-9Bgeeepithelium of colon1.00infobox
Galectin-9Bgeelymph node1.00infobox
Galectin-9Bgeepylorus1.00infobox
Galectin-9Bgeeappendix1.00infobox
Galectin-9Bgeegastric mucosa1.00infobox
Galectin-9Bgeemucous cell of stomach1.00infobox
Galectin-9Bgeeepithelium of stomach1.00infobox
Galectin-9Bgeepyloric antrum1.00infobox
Galectin-9Bgeeseminal vesicula1.00infobox
Galectin-9Bgeeleft lobe of liver1.00infobox
Galectin-9Bgeeduodenum1.00infobox
Galectin-9Bgeecrypt of lieberkuhn of small intestine1.00infobox
Galectin-9Bgeethymus1.00infobox
Galectin-9BioGPSMore reference expression data1.00infobox
Galectin-9Chr.Chromosome 17 (human)1.00infobox
Galectin-9Chr.Chromosome 11 (mouse)1.00infobox
Galectin-9DatabasesNCBI: entry; OMA: entry1.00infobox
Galectin-9End27,649,560 bp1.00infobox
Galectin-9End78,875,772 bp1.00infobox
Galectin-9EnsemblENSG000001689611.00infobox

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