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Eukaryotic translation initiation factor 4E-binding protein 1 (also known as 4E-BP1) is a protein that in humans is encoded by the EIF4EBP1 gene. It inhibits cap-dependent translation by binding to translation initiation factor eIF4E. Phosphorylation of 4E-BP1 results in its release from eIF4E, thereby allows cap-dependent translation to continue thereby…
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translation protein eif4e 4e-bp1 initiation bp human factor gene chr band eukaryotic chromosome cap-dependent binding phosphorylation location 4e end mouse
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| EIF4EBP1 | Aliases | EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I, eukaryotic translation initiation factor 4E binding protein 1 | 1.00 | infobox |
| EIF4EBP1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EJ4, 1WKW, 2JGB, 2JGC, 2V8W, 2V8X, 2V8Y, 3HXG, 3HXI, 3M93, 3M94, 3U7X, 4UED, 5BXV | 1.00 | infobox |
| EIF4EBP1 | Band | 8p11.23 | 1.00 | infobox |
| EIF4EBP1 | Band | 8 A2|8 15.95 cM | 1.00 | infobox |
| EIF4EBP1 | Bgee | body of pancreas | 1.00 | infobox |
| EIF4EBP1 | Bgee | parotid gland | 1.00 | infobox |
| EIF4EBP1 | Bgee | muscle of thigh | 1.00 | infobox |
| EIF4EBP1 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| EIF4EBP1 | Bgee | apex of heart | 1.00 | infobox |
| EIF4EBP1 | Bgee | minor salivary glands | 1.00 | infobox |
| EIF4EBP1 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| EIF4EBP1 | Bgee | right lobe of liver | 1.00 | infobox |
| EIF4EBP1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| EIF4EBP1 | Bgee | cartilage tissue | 1.00 | infobox |
| EIF4EBP1 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| EIF4EBP1 | Bgee | lacrimal gland | 1.00 | infobox |
| EIF4EBP1 | Bgee | white adipose tissue | 1.00 | infobox |
| EIF4EBP1 | Bgee | brown adipose tissue | 1.00 | infobox |
| EIF4EBP1 | Bgee | embryo | 1.00 | infobox |
| EIF4EBP1 | Bgee | granulocyte | 1.00 | infobox |
| EIF4EBP1 | Bgee | gastrula | 1.00 | infobox |
| EIF4EBP1 | Bgee | submandibular gland | 1.00 | infobox |
| EIF4EBP1 | BioGPS | More reference expression data | 1.00 | infobox |
| EIF4EBP1 | Chr. | Chromosome 8 (human) | 1.00 | infobox |
| EIF4EBP1 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| EIF4EBP1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| EIF4EBP1 | End | 38,060,365 bp | 1.00 | infobox |
| EIF4EBP1 | End | 27,766,702 bp | 1.00 | infobox |
| EIF4EBP1 | Ensembl | ENSG00000187840 | 1.00 | infobox |
| EIF4EBP1 | Entrez | 1978 | 1.00 | infobox |
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