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TPCN2

Two pore segment channel 2 (TPC2) is a protein which in humans is encoded by the TPCN2 gene. TPC2 is an ion channel, however, in contrast to other calcium and sodium channels which have four homologous domains, each containing 6 transmembrane segments (S1 to S6), TPCN1 only contains two domain (each containing segments S1 to S6).

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Aliases
TPCN2, SHEP10, TPC2, two pore segment channel 2
Band
11q13.3 · 7|7 F5
Bgee
pancreatic ductal cell · mucosa of ileum · gastric mucosa · muscle layer of sigmoid colon · body of uterus
BioGPS
n/a
Chr.
Chromosome 11 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Structure

Filoviral infections

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Map overview Semantic statistics

TPCN2

Nodes19
Edges18
Triples89
Avg. degree1.89
Density0.105263
Components1

How this topic connects Entity context

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TPCN2

Top relations

Gene ontology · 28
TPCN2 → calcium channel activity, calcium ion transmembrane transport, calcium ion transport, calcium-mediated signaling, cellular calcium ion homeostasis, endosome membrane, identical protein binding, integral component of membrane, ion channel activity, ion transmembrane transport, ion transport, lysosomal membrane, lysosome, lysosome organization, membrane, membrane depolarization during action potential, NAADP-sensitive calcium-release channel activity, plasma membrane, protein binding, protein kinase binding
Bgee · 19
TPCN2 → blastocyst, body of uterus, embryo, gastric mucosa, granulocyte, inner renal medulla, left uterine tube, lip, monocyte, mucosa of ileum, muscle layer of sigmoid colon, pancreatic ductal cell, right hemisphere of cerebellum, right lobe of liver, spermatid, stroma of bone marrow, tibialis anterior muscle, ventricular zone, yolk sac
RNA expression pattern · 19
TPCN2 → blastocyst, body of uterus, embryo, gastric mucosa, granulocyte, inner renal medulla, left uterine tube, lip, monocyte, mucosa of ileum, muscle layer of sigmoid colon, pancreatic ductal cell, right hemisphere of cerebellum, right lobe of liver, spermatid, stroma of bone marrow, tibialis anterior muscle, ventricular zone, yolk sac
related to External links · 3
TPCN2 → Medicine Medical Subject Headings, MeSH, National Library
Band · 2
TPCN2 → 11q13.3, 7|7 F5
Chr. · 2
TPCN2 → Chromosome 11 (human), Chromosome 7 (mouse)
End · 2
TPCN2 → 144,837,748 bp, 69,136,316 bp
Aliases · 1
TPCN2 → TPCN2, SHEP10, TPC2, two pore segment channel 2
BioGPS · 1
TPCN2 → n/a
Databases · 1
TPCN2 → NCBI: entry; OMA: entry

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Important terminology

channel bp tpc2 human chr band gene two chromosome 11 protein ion location tpc1 calcium mouse pore segment transmembrane external

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TPCN2AliasesTPCN2, SHEP10, TPC2, two pore segment channel 21.00infobox
TPCN2Band11q13.31.00infobox
TPCN2Band7|7 F51.00infobox
TPCN2Bgeepancreatic ductal cell1.00infobox
TPCN2Bgeemucosa of ileum1.00infobox
TPCN2Bgeegastric mucosa1.00infobox
TPCN2Bgeemuscle layer of sigmoid colon1.00infobox
TPCN2Bgeebody of uterus1.00infobox
TPCN2Bgeemonocyte1.00infobox
TPCN2Bgeeright hemisphere of cerebellum1.00infobox
TPCN2Bgeetibialis anterior muscle1.00infobox
TPCN2Bgeeleft uterine tube1.00infobox
TPCN2Bgeeright lobe of liver1.00infobox
TPCN2Bgeegranulocyte1.00infobox
TPCN2Bgeeinner renal medulla1.00infobox
TPCN2Bgeestroma of bone marrow1.00infobox
TPCN2Bgeelip1.00infobox
TPCN2Bgeeventricular zone1.00infobox
TPCN2Bgeespermatid1.00infobox
TPCN2Bgeeyolk sac1.00infobox
TPCN2Bgeeembryo1.00infobox
TPCN2Bgeeblastocyst1.00infobox
TPCN2BioGPSn/a1.00infobox
TPCN2Chr.Chromosome 11 (human)1.00infobox
TPCN2Chr.Chromosome 7 (mouse)1.00infobox
TPCN2DatabasesNCBI: entry; OMA: entry1.00infobox
TPCN2End69,136,316 bp1.00infobox
TPCN2End144,837,748 bp1.00infobox
TPCN2EnsemblENSG000001623411.00infobox
TPCN2Entrez2199311.00infobox

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