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Two pore segment channel 2 (TPC2) is a protein which in humans is encoded by the TPCN2 gene. TPC2 is an ion channel, however, in contrast to other calcium and sodium channels which have four homologous domains, each containing 6 transmembrane segments (S1 to S6), TPCN1 only contains two domain (each containing segments S1 to S6).
The analysis highlights Structure, Filoviral infections and Overview as prominent areas in the source structure around TPCN2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around TPCN2 shows recurring relationship patterns in the source. For example, TPCN2 → calcium channel activity, calcium ion transmembrane transport, calcium ion transport, calcium-mediated signaling, cellular calcium ion homeostasis, endosome membrane, identical protein binding, integral component of membrane, ion channel activity, ion transmembrane transport, ion transport, lysosomal membrane, lysosome, lysosome organization, membrane, membrane depolarization during action potential, NAADP-sensitive calcium-release channel activity, plasma membrane, protein binding, protein kinase binding Another extracted example is TPCN2 → blastocyst, body of uterus, embryo, gastric mucosa, granulocyte, inner renal medulla, left uterine tube, lip, monocyte, mucosa of ileum, muscle layer of sigmoid colon, pancreatic ductal cell, right hemisphere of cerebellum, right lobe of liver, spermatid, stroma of bone marrow, tibialis anterior muscle, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
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channel bp tpc2 human chr band gene two chromosome 11 protein ion location tpc1 calcium mouse pore segment transmembrane external
TTTA extracted 86 structured relationships around TPCN2. Examples in this analysis include TPCN2 → Aliases → TPCN2, SHEP10, TPC2, two pore segment channel 2 and TPCN2 → Band → 11q13.3. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TPCN2 | Aliases | TPCN2, SHEP10, TPC2, two pore segment channel 2 | 1.00 | infobox |
| TPCN2 | Band | 11q13.3 | 1.00 | infobox |
| TPCN2 | Band | 7|7 F5 | 1.00 | infobox |
| TPCN2 | Bgee | pancreatic ductal cell | 1.00 | infobox |
| TPCN2 | Bgee | mucosa of ileum | 1.00 | infobox |
| TPCN2 | Bgee | gastric mucosa | 1.00 | infobox |
| TPCN2 | Bgee | muscle layer of sigmoid colon | 1.00 | infobox |
| TPCN2 | Bgee | body of uterus | 1.00 | infobox |
| TPCN2 | Bgee | monocyte | 1.00 | infobox |
| TPCN2 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| TPCN2 | Bgee | tibialis anterior muscle | 1.00 | infobox |
| TPCN2 | Bgee | left uterine tube | 1.00 | infobox |
| TPCN2 | Bgee | right lobe of liver | 1.00 | infobox |
| TPCN2 | Bgee | granulocyte | 1.00 | infobox |
| TPCN2 | Bgee | inner renal medulla | 1.00 | infobox |
| TPCN2 | Bgee | stroma of bone marrow | 1.00 | infobox |
| TPCN2 | Bgee | lip | 1.00 | infobox |
| TPCN2 | Bgee | ventricular zone | 1.00 | infobox |
| TPCN2 | Bgee | spermatid | 1.00 | infobox |
| TPCN2 | Bgee | yolk sac | 1.00 | infobox |
| TPCN2 | Bgee | embryo | 1.00 | infobox |
| TPCN2 | Bgee | blastocyst | 1.00 | infobox |
| TPCN2 | BioGPS | n/a | 1.00 | infobox |
| TPCN2 | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| TPCN2 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| TPCN2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TPCN2 | End | 69,136,316 bp | 1.00 | infobox |
| TPCN2 | End | 144,837,748 bp | 1.00 | infobox |
| TPCN2 | Ensembl | ENSG00000162341 | 1.00 | infobox |
| TPCN2 | Entrez | 219931 | 1.00 | infobox |
The concept neighborhoods around TPCN2 bring nearby vocabulary together. In this analysis, examples include Gene, Human and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TPCN2, one of the stronger structural bridges in this analysis connects TPCN2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TPCN2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Filoviral infections & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TPCN2 · EN edition · Analysis: TopicsToTalkAbout