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Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is also known as human accelerated region 20 (HAR20). It may, therefore, have played a key role in differentiating humans from apes.
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gene protein human ppargc1a also bp mitochondrial chr band receptor akt coactivator external muscle shown gamma expression chromosome alpha nf-kappa-b
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PGC-1α | Aliases | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1, PGC-1alpha, PPARG coactivator 1 alpha, PGC-1α | 1.00 | infobox |
| PGC-1α | Band | 4p15.2 | 1.00 | infobox |
| PGC-1α | Band | 5|5 C1 | 1.00 | infobox |
| PGC-1α | Chr. | Chromosome 4 (human) | 1.00 | infobox |
| PGC-1α | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| PGC-1α | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PGC-1α | End | 23,904,089 bp | 1.00 | infobox |
| PGC-1α | End | 51,725,068 bp | 1.00 | infobox |
| PGC-1α | Ensembl | ENSG00000109819 | 1.00 | infobox |
| PGC-1α | Entrez | 10891 | 1.00 | infobox |
| PGC-1α | External IDs | OMIM: 604517; MGI: 1342774; GeneCards: PPARGC1A | 1.00 | infobox |
| PGC-1α | Gene location (Human) | Gene location (Human)Chr.Chromosome 4 (human)Band4p15.2Start23,755,041 bpEnd23,904,089 bp | 1.00 | infobox |
| PGC-1α | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 5 (mouse)Band5|5 C1Start51,611,592 bpEnd51,725,068 bp | 1.00 | infobox |
| PGC-1α | Location (UCSC) | Chr 4: 23.76 – 23.9 Mb | 1.00 | infobox |
| PGC-1α | Orthologs | OrthologsDatabasesNCBI: entry; OMA: entrySpeciesHumanMouseEntrez1089119017EnsemblENSG00000109819ENSMUSG00000029167UniProtn aO70343RefSeq (mRNA)NM_013261NM_008904RefSeq (protein)… | 1.00 | infobox |
| PGC-1α | RefSeq (mRNA) | NM_013261 | 1.00 | infobox |
| PGC-1α | RefSeq (protein) | n/a | 1.00 | infobox |
| PGC-1α | Species | Human | 1.00 | infobox |
| PGC-1α | UniProt | n a | 1.00 | infobox |
| PGC-1α | is a | master regulator of mitochondrial biogenesis | 0.90 | text |
| PGC-1α | is a | transcriptional coactivator that regulates the genes involved in energy metabolism | 0.90 | text |
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