Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

RHEB: Regions, Function & Interactions

RHEB also known as Ras homolog enriched in brain (RHEB) is a GTP-binding protein that is ubiquitously expressed in humans and other mammals. The protein is largely involved in the mTOR pathway and the regulation of the cell cycle.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

RHEB topic overview

The analysis highlights Regions, Function and Interactions as prominent areas in the source structure around RHEB.

Related topics
29
Source areas
5
Connected nodes
34
Extracted relationships
167
Concept neighborhoods
16
Bridge connections
34

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 13 topics
Interactions · 8 topics
Overview · 5 topics
Structure · 2 topics
Regulation · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
RHEB, RHEB2, Ras homolog enriched in brain, Ras homolog, mTORC1 binding
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XTQ, 1XTR, 1XTS, 3SEA, 3T5G
Band
7q36.1 · 5|5 A3
Bgee
ventricular zone · ganglionic eminence · smooth muscle tissue · Brodmann area 9 · gastric mucosa
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Regulation

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How RHEB connects Entity context

The extracted context around RHEB shows recurring relationship patterns in the source. For example, RHEB → cytoplasm, cytosol, endomembrane system, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular exosome, GDP binding, Golgi apparatus, Golgi membrane, GTP binding, GTPase activity, lysosomal membrane, magnesium ion binding, membrane, metal ion binding, negative regulation of cold-induced thermogenesis, nucleotide binding, plasma membrane, positive regulation of oligodendrocyte differentiation, positive regulation of TOR signaling Another extracted example is RHEB → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, condyle, Epithelium of choroid plexus, facial motor nucleus, ganglionic eminence, gastric mucosa, left adrenal cortex, medial ganglionic eminence, muscle layer of sigmoid colon, nucleus of stria terminalis, otic placode, otic vesicle, Region I of hippocampus proper, right frontal lobe, saccule, smooth muscle tissue, ventricular zone, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.

RHEB

Top relations

Gene ontology · 29
RHEB → cytoplasm, cytosol, endomembrane system, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular exosome, GDP binding, Golgi apparatus, Golgi membrane, GTP binding, GTPase activity, lysosomal membrane, magnesium ion binding, membrane, metal ion binding, negative regulation of cold-induced thermogenesis, nucleotide binding, plasma membrane, positive regulation of oligodendrocyte differentiation, positive regulation of TOR signaling
Bgee · 20
RHEB → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, condyle, Epithelium of choroid plexus, facial motor nucleus, ganglionic eminence, gastric mucosa, left adrenal cortex, medial ganglionic eminence, muscle layer of sigmoid colon, nucleus of stria terminalis, otic placode, otic vesicle, Region I of hippocampus proper, right frontal lobe, saccule, smooth muscle tissue, ventricular zone, vestibular sensory epithelium
RNA expression pattern · 20
RHEB → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, condyle, Epithelium of choroid plexus, facial motor nucleus, ganglionic eminence, gastric mucosa, left adrenal cortex, medial ganglionic eminence, muscle layer of sigmoid colon, nucleus of stria terminalis, otic placode, otic vesicle, Region I of hippocampus proper, right frontal lobe, saccule, smooth muscle tissue, ventricular zone, vestibular sensory epithelium
related to Interactions · 17
RHEB → AMP-activated, AMPK, Ataxia, ATM, ATR, C-Raf, CAD, Phospholipase D1, PLD1, Rad3, RAF, Rapamycin Complex, Regulatory-associated, RPTOR, Target, TSC, Tuberous
related to Differences from Ras superfamily · 10
RHEB → Asp65, GDP-bound, GTP, GTP-bound, GTPase, However, II, Ras, Similar, Such
related to Structure · 10
RHEB → Also, C-terminus, CAAX, GDP-bound, GTP-bound, GTPase, II, N-terminus, RAS-related GTP-binding, The
related to Activation of mTORC1 · 7
RHEB → GTP-bound, GTP-bound RHEB, Mechanistic Target, Rag7, Ragulator-Rag, Rapamycin Complex, TOR/S6K
related to mTORC1 independent functions · 7
RHEB → AMPK, An, CAD, For, In, Phospholipase D1, PLD1
related to Regulation · 7
RHEB → GTP, GTP-bound, Its, Specifically, TSC, TSC2, Tuberin
related to External links · 6
RHEB → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ras cell protein mtorc1 human mtor bp pathway complex chr band within proteins chromosome superfamily function regulation also growth tuberous

RHEB relationships Subject–Predicate–Object triples

TTTA extracted 167 structured relationships around RHEB. Examples in this analysis include RHEB → Aliases → RHEB, RHEB2, Ras homolog enriched in brain, Ras homolog, mTORC1 binding and RHEB → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XTQ, 1XTR, 1XTS, 3SEA, 3T5G. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
RHEBAliasesRHEB, RHEB2, Ras homolog enriched in brain, Ras homolog, mTORC1 binding1.00infobox
RHEBAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XTQ, 1XTR, 1XTS, 3SEA, 3T5G1.00infobox
RHEBBand7q36.11.00infobox
RHEBBand5|5 A31.00infobox
RHEBBgeeventricular zone1.00infobox
RHEBBgeeganglionic eminence1.00infobox
RHEBBgeesmooth muscle tissue1.00infobox
RHEBBgeeBrodmann area 91.00infobox
RHEBBgeegastric mucosa1.00infobox
RHEBBgeecingulate gyrus1.00infobox
RHEBBgeeanterior cingulate cortex1.00infobox
RHEBBgeemuscle layer of sigmoid colon1.00infobox
RHEBBgeeleft adrenal cortex1.00infobox
RHEBBgeeright frontal lobe1.00infobox
RHEBBgeeotic vesicle1.00infobox
RHEBBgeeEpithelium of choroid plexus1.00infobox
RHEBBgeesaccule1.00infobox
RHEBBgeeRegion I of hippocampus proper1.00infobox
RHEBBgeeotic placode1.00infobox
RHEBBgeefacial motor nucleus1.00infobox
RHEBBgeecondyle1.00infobox
RHEBBgeevestibular sensory epithelium1.00infobox
RHEBBgeenucleus of stria terminalis1.00infobox
RHEBBgeemedial ganglionic eminence1.00infobox
RHEBBioGPSMore reference expression data1.00infobox
RHEBChr.Chromosome 7 (human)1.00infobox
RHEBChr.Chromosome 5 (mouse)1.00infobox
RHEBDatabasesNCBI: entry; OMA: entry1.00infobox
RHEBEnd151,520,120 bp1.00infobox
RHEBEnd25,047,622 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around RHEB bring nearby vocabulary together. In this analysis, examples include Mtorc1, Gtp and Growth. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • RHEB
    • Mtorc1
    • Gtp
    • Growth
    • Human
    • Within
    • Complex
    • Proteins
    • Binding
    • Nucleotide
    • Ampk
    • Due
    • Gene
  • rheb
    • Mtorc1
    • Gtp
    • Growth
    • Human
    • Within
    • Complex
    • Proteins
    • Binding
    • Nucleotide
    • Ampk
    • Due
    • Gene
  • gtp-binding protein
    • Kinase
    • Complex
    • Ampk
    • Expressed
    • Rheb
    • Region
    • Regulation
    • Activity
    • Human
    • Mtor
    • Mtorc1
    • Ras
  • ras superfamily
    • Superfamily
    • Ii
    • Switch
    • Rheb
    • Due
    • Function
    • Human
    • Proteins
    • Gtp-bound
    • Required
    • Tuberous
    • Activity
  • ras
    • Superfamily
    • Ii
    • Switch
    • Rheb
    • Due
    • Function
    • Human
    • Proteins
    • Protein
    • Binding
    • Expressed
    • Location
  • tuberous sclerosis
    • Sclerosis
    • Tuberous
    • Function
    • Human
    • Complex
    • Mtor
    • Mtorc1
    • Binding
    • Location
    • Ampk
    • Gene
    • Regulation
  • cell cycle
    • Within
    • Growth
    • Lead
    • Activity
    • Regulation
    • Rheb
    • Form
    • Pathway
    • Complex
    • Mtorc1
    • Involved
    • Nucleotide
  • 5' adenosine-monophosphate-activated protein kinase
    • Ampk
    • Kinase
    • Protein
    • Complex
    • Expressed
    • Mtorc1
    • Rheb
    • Region
    • Regulation
    • Activity
    • Human
    • Location

Connections between topic areas Semantic bridges

For RHEB, one of the stronger structural bridges in this analysis connects RHEB with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
RHEBFunction · splits 21 ⟂ 14
RHEBInteractions · splits 26 ⟂ 9
RHEBOverview · splits 29 ⟂ 6
RHEBStructure · splits 32 ⟂ 3

Map overview Semantic statistics

RHEB

Nodes35
Edges34
Triples167
Avg. degree1.94
Density0.057143
Components1

Source & methodology

TTTA analyzes the structure around RHEB to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — RHEB · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.