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FKBP: Applications, Research & Standards

The FKBPs, or FK506 binding proteins, constitute a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function, though not in amino acid sequence. FKBPs have been identified in many eukaryotes, ranging from yeast to humans, and function as protein folding chaperones for proteins containing proline residues.…

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FKBP topic overview

The analysis highlights Applications, Research and Standards as prominent areas in the source structure around FKBP.

Related topics
40
Source areas
3
Connected nodes
43
Extracted relationships
33
Concept neighborhoods
23
Bridge connections
43

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 22 topics
Examples · 16 topics
Use as a biological research tool · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR001179 · PF00254
Available protein structures:
IPR001179 · PF00254
InterPro
IPR001179
Membranome
336
PDB
IPR001179 PF00254 (ECOD; PDBsum)
Pfam
PF00254

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Use as a biological research tool

Examples

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How FKBP connects Entity context

The extracted context around FKBP shows recurring relationship patterns in the source. For example, FKBP → AIP, AIPL1FKBPL, FKBP10, FKBP11, FKBP14, FKBP15, FKBP1A, FKBP1B, FKBP1C, FKBP2, FKBP3, FKBP4, FKBP5, FKBP6, FKBP7, FKBP8, FKBP9, Human Another extracted example is FKBP → FK1012, FK506, FKBP1A, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

FKBP

Top relations

related to Examples · 18
FKBP → AIP, AIPL1FKBPL, FKBP10, FKBP11, FKBP14, FKBP15, FKBP1A, FKBP1B, FKBP1C, FKBP2, FKBP3, FKBP4, FKBP5, FKBP6, FKBP7, FKBP8, FKBP9, Human
related to Use as a biological research tool · 4
FKBP → FK1012, FK506, FKBP1A, This
AlphaFold · 2
FKBP → IPR001179, PF00254
Available protein structures: · 2
FKBP → IPR001179, PF00254
InterPro · 1
FKBP → IPR001179
Membranome · 1
FKBP → 336
PDB · 1
FKBP → IPR001179 PF00254 (ECOD; PDBsum)
Pfam · 1
FKBP → PF00254
PROSITE · 1
FKBP → PDOC00426
SCOP2 · 1
FKBP → 1fkb / SCOPe / SUPFAM

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein tacrolimus fk506 fkbps related proteins humans family fkbp1a binding prolyl isomerase activity function cyclophilin organ binds role also fkbp12

FKBP relationships Subject–Predicate–Object triples

TTTA extracted 33 structured relationships around FKBP. Examples in this analysis include FKBP → AlphaFold → IPR001179 and FKBP → AlphaFold → PF00254. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FKBPAlphaFoldIPR0011791.00infobox
FKBPAlphaFoldPF002541.00infobox
FKBPAvailable protein structures:IPR0011791.00infobox
FKBPAvailable protein structures:PF002541.00infobox
FKBPInterProIPR0011791.00infobox
FKBPMembranome3361.00infobox
FKBPPDBIPR001179 PF00254 (ECOD; PDBsum)1.00infobox
FKBPPfamPF002541.00infobox
FKBPPROSITEPDOC004261.00infobox
FKBPSCOP21fkb / SCOPe / SUPFAM1.00infobox
FKBPSymbolFKBP_C1.00infobox
FKBPrelated to ExamplesHuman0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around FKBP bring nearby vocabulary together. In this analysis, examples include Role, Fkbp1a and Tacrolimus. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • fk506
    • Tacrolimus
    • Also
    • Binding
    • Fkbp12
    • Fkbp1a
    • Protein
    • Amino
    • Autoimmune
    • Constitute
    • Cyclophilins
    • Immunosuppressant
    • Though
  • humans
    • Fkbp1a
    • Proteins
    • Autoimmune
    • Immunosuppressant
    • Proline
    • Yeast
    • Also
    • Fkbp12
    • Human
    • Organ
    • Used
    • Tacrolimus
  • protein folding
    • Bound
    • Tool
    • Tacrolimus
    • Proline
    • Yeast
    • Also
    • Drug
    • Fkbp
    • Fkbp12
    • Human
    • Used
    • Fkbp1a
  • amino acid sequence
    • Constitute
    • Cyclophilins
    • Though
    • Binding
    • Function
    • Isomerase
    • Prolyl
    • Family
    • Fkbps
    • Proteins
    • Related
    • Fk506
  • proteins
    • Function
    • Humans
    • Chaperones
    • Eukaryotes
    • Proline
    • Though
    • Yeast
    • Human
    • Fkbp1a
    • Related
    • Protein
  • fkbp1a
    • Humans
    • Tacrolimus
    • Autoimmune
    • Immunosuppressant
    • Drug
    • Fkbp
    • Human
    • Organ
    • Used
    • Proteins
    • Protein
  • cyclophilins
    • Amino
    • Though
    • Function
    • Isomerase
    • Prolyl
    • Family
    • Fkbps
    • Proteins
    • Related
    • Fk506
  • tacrolimus
    • Drug
    • Organ
    • Ciclosporin
    • Binds
    • Bound
    • Fkbp
    • Human
    • Tool
    • Used

Connections between topic areas Semantic bridges

For FKBP, one of the stronger structural bridges in this analysis connects FKBP with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FKBPOverview · splits 21 ⟂ 23
FKBPExamples · splits 27 ⟂ 17
FKBPUse as a biological research tool · splits 41 ⟂ 3

Map overview Semantic statistics

FKBP

Nodes44
Edges43
Triples33
Avg. degree1.95
Density0.045455
Components1

Source & methodology

TTTA analyzes the structure around FKBP to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Research & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — FKBP · EN edition · Analysis: TopicsToTalkAbout

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