Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Galectin-3

Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have been identified.

Applications, Clinical significance & Function

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Galectin-3. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, lectin, galactoside binding soluble 3, galectin 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A3K, 1KJL, 1KJR, 2NMN, 2NMO, 2NN8, 2XG3, 3AYA, 3AYC, 3AYD, 3AYE, 3T1L, 3T1M, 3ZSJ, 3ZSK, 3ZSL, 3ZSM, 4BLI,…
Band
14q22.3 · 14|14 C1
Bgee
mucosa of colon · palpebral conjunctiva · mucosa of sigmoid colon · bronchial epithelial cell · nasal epithelium
BioGPS
More reference expression data
Chr.
Chromosome 14 (human) · Chromosome 14 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Clinical applications

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Galectin-3

Nodes119
Edges118
Triples171
Avg. degree1.98
Density0.016807
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Galectin-3

Top relations

Gene ontology · 54
Galectin-3 → antimicrobial humoral immune response mediated by antimicrobial peptide, carbohydrate binding, cell differentiation, cell surface, chemoattractant activity, collagen-containing extracellular matrix, cytoplasm, eosinophil chemotaxis, epithelial cell differentiation, extracellular exosome, extracellular matrix, extracellular region, extracellular space, ficolin-1-rich granule membrane, galectin complex, IgE binding, immune system process, immunological synapse, innate immune response, laminin binding
Bgee · 19
Galectin-3 → amniotic fluid, bronchial epithelial cell, calvaria, decidua, gastrula, granulocyte, jejunal mucosa, left colon, lip, mucosa of colon, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, nasal epithelium, palpebral conjunctiva, skin of abdomen, skin of external ear, stroma of bone marrow, transitional epithelium of urinary bladder
RNA expression pattern · 19
Galectin-3 → amniotic fluid, bronchial epithelial cell, calvaria, decidua, gastrula, granulocyte, jejunal mucosa, left colon, lip, mucosa of colon, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, nasal epithelium, palpebral conjunctiva, skin of abdomen, skin of external ear, stroma of bone marrow, transitional epithelium of urinary bladder
related to Cardiovascular risk indicator · 12
Galectin-3 → Abbott, ARCHITECT, BG Medicine, Chronic, EcoNugenics, Fibrosis, Isaac Eliaz, LV, Pecta-Sol, The, This, VIDAS
related to Early neurodevelopment · 10
Galectin-3 → BMP, BMPR1α, Details, EGFR-based, In, Increasing, Knockdown, SVZ, V-SVZ, Wnt
related to Drug development · 8
Galectin-3 → Earlier, Galectin Therapeutics, Galecto Biotech, In, MASH, Preclinical, Sweden, United States
related to Fibrosis · 6
Galectin-3 → Companies, GR-MD-02, In, IPF, TD139, The
related to Cardiovascular disease · 5
Galectin-3 → Elevated, For, However, In, One
related to Brain injury and stroke · 4
Galectin-3 → In, It, Reactive, VEGF
related to Cancer · 3
Galectin-3 → Altered, Overexpression, The

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fibrosis also cancer expression human gene 14 galectins lgals3 bp cell shown binding chromosome angiogenesis chr protein band heart cells

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Galectin-3AliasesLGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, lectin, galactoside binding soluble 3, galectin 31.00infobox
Galectin-3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A3K, 1KJL, 1KJR, 2NMN, 2NMO, 2NN8, 2XG3, 3AYA, 3AYC, 3AYD, 3AYE, 3T1L, 3T1M, 3ZSJ, 3ZSK, 3ZSL, 3ZSM, 4BLI,…1.00infobox
Galectin-3Band14q22.31.00infobox
Galectin-3Band14|14 C11.00infobox
Galectin-3Bgeemucosa of colon1.00infobox
Galectin-3Bgeepalpebral conjunctiva1.00infobox
Galectin-3Bgeemucosa of sigmoid colon1.00infobox
Galectin-3Bgeebronchial epithelial cell1.00infobox
Galectin-3Bgeenasal epithelium1.00infobox
Galectin-3Bgeedecidua1.00infobox
Galectin-3Bgeemucosa of ileum1.00infobox
Galectin-3Bgeejejunal mucosa1.00infobox
Galectin-3Bgeemucosa of transverse colon1.00infobox
Galectin-3Bgeeamniotic fluid1.00infobox
Galectin-3Bgeeskin of external ear1.00infobox
Galectin-3Bgeeleft colon1.00infobox
Galectin-3Bgeetransitional epithelium of urinary bladder1.00infobox
Galectin-3Bgeecalvaria1.00infobox
Galectin-3Bgeegranulocyte1.00infobox
Galectin-3Bgeegastrula1.00infobox
Galectin-3Bgeestroma of bone marrow1.00infobox
Galectin-3Bgeelip1.00infobox
Galectin-3Bgeeskin of abdomen1.00infobox
Galectin-3BioGPSMore reference expression data1.00infobox
Galectin-3Chr.Chromosome 14 (human)1.00infobox
Galectin-3Chr.Chromosome 14 (mouse)1.00infobox
Galectin-3DatabasesNCBI: entry; OMA: entry1.00infobox
Galectin-3End55,145,423 bp1.00infobox
Galectin-3End47,623,617 bp1.00infobox
Galectin-3EnsemblENSG000001319811.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.