Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Eukaryotic translation initiation factor 4E-binding protein 1 (also known as 4E-BP1) is a protein that in humans is encoded by the EIF4EBP1 gene. It inhibits cap-dependent translation by binding to translation initiation factor eIF4E. Phosphorylation of 4E-BP1 results in its release from eIF4E, thereby allows cap-dependent translation to continue thereby…
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around EIF4EBP1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Explore different angles and find fresh ideas to shape your next piece of content.
Search suggestions related to this topic. Open a question to research it further; suggestions are not verified answers.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
You can skip this section if you’re here for content ideas and keyword inspiration.
The extracted context around EIF4EBP1 shows recurring relationship patterns in the source. For example, EIF4EBP1 → cellular response to dexamethasone stimulus, cellular response to hypoxia, cytoplasm, cytosol, eukaryotic initiation factor 4E binding, G1/S transition of mitotic cell cycle, glutamatergic synapse, insulin receptor signaling pathway, IRES-dependent translational initiation of linear mRNA, lung development, negative regulation of protein-containing complex assembly, negative regulation of translation, negative regulation of translational initiation, nucleus, positive regulation of mitotic cell cycle, postsynaptic cytosol, protein binding, protein phosphatase 2A binding, protein-containing complex, regulation of translation Another extracted example is EIF4EBP1 → apex of heart, body of pancreas, brown adipose tissue, cartilage tissue, embryo, endothelial cell of lymphatic vessel, gastrocnemius muscle, gastrula, granulocyte, lacrimal gland, minor salivary glands, muscle of thigh, olfactory zone of nasal mucosa, parotid gland, right lobe of liver, stromal cell of endometrium, submandibular gland, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
translation protein eif4e 4e-bp1 initiation bp human factor gene chr band eukaryotic chromosome cap-dependent binding phosphorylation location 4e end mouse
TTTA extracted 87 structured relationships around EIF4EBP1. Examples in this analysis include EIF4EBP1 → Aliases → EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I, eukaryotic translation initiation factor 4E binding protein 1 and EIF4EBP1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EJ4, 1WKW, 2JGB, 2JGC, 2V8W, 2V8X, 2V8Y, 3HXG, 3HXI, 3M93, 3M94, 3U7X, 4UED, 5BXV. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| EIF4EBP1 | Aliases | EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I, eukaryotic translation initiation factor 4E binding protein 1 | 1.00 | infobox |
| EIF4EBP1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EJ4, 1WKW, 2JGB, 2JGC, 2V8W, 2V8X, 2V8Y, 3HXG, 3HXI, 3M93, 3M94, 3U7X, 4UED, 5BXV | 1.00 | infobox |
| EIF4EBP1 | Band | 8p11.23 | 1.00 | infobox |
| EIF4EBP1 | Band | 8 A2|8 15.95 cM | 1.00 | infobox |
| EIF4EBP1 | Bgee | body of pancreas | 1.00 | infobox |
| EIF4EBP1 | Bgee | parotid gland | 1.00 | infobox |
| EIF4EBP1 | Bgee | muscle of thigh | 1.00 | infobox |
| EIF4EBP1 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| EIF4EBP1 | Bgee | apex of heart | 1.00 | infobox |
| EIF4EBP1 | Bgee | minor salivary glands | 1.00 | infobox |
| EIF4EBP1 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| EIF4EBP1 | Bgee | right lobe of liver | 1.00 | infobox |
| EIF4EBP1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| EIF4EBP1 | Bgee | cartilage tissue | 1.00 | infobox |
| EIF4EBP1 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| EIF4EBP1 | Bgee | lacrimal gland | 1.00 | infobox |
| EIF4EBP1 | Bgee | white adipose tissue | 1.00 | infobox |
| EIF4EBP1 | Bgee | brown adipose tissue | 1.00 | infobox |
| EIF4EBP1 | Bgee | embryo | 1.00 | infobox |
| EIF4EBP1 | Bgee | granulocyte | 1.00 | infobox |
| EIF4EBP1 | Bgee | gastrula | 1.00 | infobox |
| EIF4EBP1 | Bgee | submandibular gland | 1.00 | infobox |
| EIF4EBP1 | BioGPS | More reference expression data | 1.00 | infobox |
| EIF4EBP1 | Chr. | Chromosome 8 (human) | 1.00 | infobox |
| EIF4EBP1 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| EIF4EBP1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| EIF4EBP1 | End | 38,060,365 bp | 1.00 | infobox |
| EIF4EBP1 | End | 27,766,702 bp | 1.00 | infobox |
| EIF4EBP1 | Ensembl | ENSG00000187840 | 1.00 | infobox |
| EIF4EBP1 | Entrez | 1978 | 1.00 | infobox |
The concept neighborhoods around EIF4EBP1 bring nearby vocabulary together. In this analysis, examples include Eukaryotic, Factor and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For EIF4EBP1, one of the stronger structural bridges in this analysis connects EIF4EBP1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around EIF4EBP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — EIF4EBP1 · EN edition · Analysis: TopicsToTalkAbout