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Propranolol

Propranolol is a medication of the beta blocker class. It is used to treat high blood pressure, some types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, akathisia, performance anxiety, and essential tremors, as well as to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks. It…

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Key facts & relationships

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3D model (JSmol)
Interactive image · as HCl: Interactive image
AHFS/Drugs.com
Monograph
ATC code
C07AA05 (WHO) C07FX01 (WHO), C07BA05 (WHO)
Bioavailability
Oral: 25% Sublingual: 63% Intranasal: ~100%
CAS Number
525-66-6 · as HCl: 318-98-9
ChEBI
CHEBI:8499 · as HCl: CHEBI:8500

Topics to explore

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Overview

Medical uses

Contraindications

Side effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Propranolol

Nodes315
Edges314
Triples200
Avg. degree1.99
Density0.006349
Components1

How this topic connects Entity context

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Propranolol

Top relations

related to Brand names · 21
Propranolol → Alderley Park, Alderlin, Anaprilin, AstraZeneca, Avlocardyl, Bedranol SR, Cipla, Ciplar, Ciplar LA, Deralin, Dociton, Hemangeol, ICI, ICI Pharmaceuticals, In India, Inderal, Inderalici, Indoblok, InnoPran XL, Sandoz
has effect · 19
Propranolol → Alcohol, Aluminum, Chlorpromazine, Cigarette, Conversely, CYP1A2, CYP2C19, CYP2D6, CYP450, High-dose, It, Levels, No, P450, T3, T4, The, The CYP1A2, The CYP2D6
related to External links · 11
Propranolol → C29382, C62073, Code, EVS Explore, Infantile Hemangioma, Media, MedlinePlus, MedlinePlus Drug Information, Propranolol Hydrochloride, Wikimedia Commons, Wiktionary-logo-en-v2
related to Pharmacodynamic interactions · 10
Propranolol → ACE, Hypotension, MAOIs, Nonsteroidal, NSAIDs, Pharmacodynamic, Since, TCAs, The NSAID, Tricyclic
related to history · 9
Propranolol → Black, It, James, Medicine, Newer, Nobel Prize, Physiology, Scottish, WHO Model
related to Performance enhancement · 8
Propranolol → For, In, International Conference, It, Kim Jong-su, Opera Musicians, Summer Olympics, Symphony
related to Pharmacodynamics · 8
Propranolol → HT1A, HT1B, HT2B, In, It, Since, The, Therefore
related to Pregnancy and lactation · 7
Propranolol → ADEC, American Academy, Australian Drug Evaluation Committee, Beta-blocking, Pediatrics, The, These
Legal status · 6
Propranolol → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, SE: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Anxiety and related disorders · 6
Propranolol → Although, Findings, However, It, Its, This

Important terminology Word statistics

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Important terminology

beta levels may effects blockers blood treatment found including increase cyp2d6 drugs used blocker heart metabolism cyp1a2 anxiety area-under-the-curve symptoms

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Propranolol3D model (JSmol)Interactive image1.00infobox
Propranolol3D model (JSmol)as HCl: Interactive image1.00infobox
PropranololAHFS/Drugs.comMonograph1.00infobox
PropranololATC codeC07AA05 (WHO) C07FX01 (WHO), C07BA05 (WHO)1.00infobox
PropranololBioavailabilityOral: 25% Sublingual: 63% Intranasal: ~100%1.00infobox
PropranololCAS Number525-66-61.00infobox
PropranololCAS Numberas HCl: 318-98-91.00infobox
PropranololChEBICHEBI:84991.00infobox
PropranololChEBIas HCl: CHEBI:85001.00infobox
PropranololChEMBLChEMBL271.00infobox
PropranololChEMBLas HCl: ChEMBL16711.00infobox
PropranololChemSpider47771.00infobox
PropranololChemSpideras HCl: 566101.00infobox
PropranololChiralityRacemic mixture1.00infobox
PropranololCompTox Dashboard (EPA)DTXSID60235251.00infobox
PropranololDrug classBeta blocker1.00infobox
PropranololDrugBankDB005711.00infobox
PropranololDrugBankas HCl: DBSALT0005491.00infobox
PropranololDuration of actionUp to 12 hours1.00infobox
PropranololECHA InfoCard100.007.6181.00infobox
PropranololElimination half-life~4 hours (range 3–8 hours)1.00infobox
PropranololExcretionUrine: 91%1.00infobox
PropranololFormulaC16H21NO21.00infobox
PropranololIUPHAR/BPS5641.00infobox
PropranololKEGGD084431.00infobox
PropranololKEGGas HCl: D004831.00infobox
PropranololLegal statusAU: S4 (Prescription only)1.00infobox
PropranololLegal statusCA: ℞-only1.00infobox
PropranololLegal statusUK: POM (Prescription only)1.00infobox
PropranololLegal statusUS: ℞-only1.00infobox

Related concept clusters Concept neighborhoods

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