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Fluvoxamine: History, Applications, Research & Standards

Fluvoxamine, sold under the brand name Luvox among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is primarily used to treat major depressive disorder and, perhaps more especially, obsessive–compulsive disorder (OCD), but is also used to treat anxiety disorders such as panic disorder, social anxiety disorder…

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Fluvoxamine topic overview

The analysis highlights History, Applications, Research and Standards as prominent areas in the source structure around Fluvoxamine.

Related topics
151
Source areas
8
Connected nodes
159
Extracted relationships
119
Concept neighborhoods
27
Bridge connections
159

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 64 topics
Adverse effects · 36 topics
Overview · 21 topics
Pharmacology · 12 topics
Medical uses · 10 topics
History · 6 topics
Environment · 1 topics
Research directions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N06AB08 (WHO)
Bioavailability
53% (90% confidence interval: 44–62%)
CAS Number
54739-18-3 Y
ChEBI
CHEBI:5138 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Interactions

Pharmacology

History

Research directions

Environment

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Fluvoxamine connects Entity context

The extracted context around Fluvoxamine shows recurring relationship patterns in the source. For example, Fluvoxamine → Abbott, Abbott Laboratories, At, BayPharma, Belgium, Drug Administration, FDA, Floxyfral, Food, In India, In Japan, It, Kali-Duphar, Luvox, Manufacturers, OCD, Solvay Pharmaceuticals, SSRI, Switzerland, Synthon Another extracted example is Fluvoxamine → Australia, In, In Japan, OCD, Of, Russia, SSRIs, The NICE, There, United Kingdom, United States. Use these groups to spot repeated connection types before inspecting the individual relationships.

Fluvoxamine

Top relations

related to history · 25
Fluvoxamine → Abbott, Abbott Laboratories, At, BayPharma, Belgium, Drug Administration, FDA, Floxyfral, Food, In India, In Japan, It, Kali-Duphar, Luvox, Manufacturers, OCD, Solvay Pharmaceuticals, SSRI, Switzerland, Synthon
related to Medical uses · 11
Fluvoxamine → Australia, In, In Japan, OCD, Of, Russia, SSRIs, The NICE, There, United Kingdom, United States
related to Post-SSRI sexual dysfunction · 9
Fluvoxamine → Characteristic, EMA's, Post-SSRI, PSSD, SNRIs, SRI, SSRIs, The, The DSM-5
related to Pharmacokinetics · 8
Fluvoxamine → CYP1A2, CYP2D6, CYP3A4, However, In, Literature, Steady-state, The
has effect · 7
Fluvoxamine → Fluvoxamine's, Gastrointestinal, However, In, It, Mosapride, SSRIs
related to Interactions · 7
Fluvoxamine → CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, P450
related to Research directions · 7
Fluvoxamine → COVID-19, Drug Administration, FDA, Food, In May, The, While
Legal status · 5
Fluvoxamine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
related to Pharmacodynamics · 5
Fluvoxamine → It, SSRI, SSRIs, This, Unlike
related to Environment · 2
Fluvoxamine → Christensen, European Union

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

may ssris effects ssri serotonin anxiety also treatment sexual drug etc dysfunction reuptake ocd risk cyp2d6 cyp1a2 mg disorder social

Fluvoxamine relationships Subject–Predicate–Object triples

TTTA extracted 119 structured relationships around Fluvoxamine. Examples in this analysis include Fluvoxamine → 3D model (JSmol) → Interactive image and Fluvoxamine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Fluvoxamine3D model (JSmol)Interactive image1.00infobox
FluvoxamineAHFS/Drugs.comMonograph1.00infobox
FluvoxamineATC codeN06AB08 (WHO)1.00infobox
FluvoxamineBioavailability53% (90% confidence interval: 44–62%)1.00infobox
FluvoxamineCAS Number54739-18-3 Y1.00infobox
FluvoxamineChEBICHEBI:5138 Y1.00infobox
FluvoxamineChEMBLChEMBL814 Y1.00infobox
FluvoxamineChemSpider4481878 Y1.00infobox
FluvoxamineCompTox Dashboard (EPA)DTXSID20440021.00infobox
FluvoxamineDrug classSelective serotonin reuptake inhibitor (SSRI)1.00infobox
FluvoxamineDrugBankDB00176 N1.00infobox
FluvoxamineECHA InfoCard100.125.4761.00infobox
FluvoxamineElimination half-life12–13 hours (single dose), 22 hours (repeated dosing)1.00infobox
FluvoxamineExcretionKidney (98%; 94% as metabolites, 4% as unchanged drug)1.00infobox
FluvoxamineFormulaC15H21F3N2O21.00infobox
FluvoxamineIUPHAR/BPS71891.00infobox
FluvoxamineKEGGD07984 Y1.00infobox
FluvoxamineLegal statusAU: S4 (Prescription only)1.00infobox
FluvoxamineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
FluvoxamineLegal statusCA: ℞-only1.00infobox
FluvoxamineLegal statusUK: POM (Prescription only)1.00infobox
FluvoxamineLegal statusUS: ℞-only1.00infobox
FluvoxamineLicense dataUS DailyMed: Fluvoxamine1.00infobox
FluvoxamineMedlinePlusa6950041.00infobox
FluvoxamineMetabolismLiver (primarily O-demethylation) Major: CYP2D6 or CYP1A2 Minor: CYP3A4, CYP2C19, and/or CYP1A21.00infobox
FluvoxamineMolar mass318.340 g·mol−11.00infobox
FluvoxaminePregnancy categoryAU: C1.00infobox
FluvoxaminePronunciationfloo-VAHK-sə-meen UK: /fluːˈvɒksəmiːn/ US: /fluːˈvɑːksəˌmiːn/1.00infobox
FluvoxamineProtein binding77–80%1.00infobox
FluvoxaminePubChem CID53243461.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Fluvoxamine bring nearby vocabulary together. In this analysis, examples include May, Increase and Ssri. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Fluvoxamine
    • May
    • Increase
    • Ssri
    • Serotonin
    • Ssris
    • Cyp1a2
    • Effective
    • Mg
    • Reuptake
    • Treatment
    • Metabolized
    • Cyp2d6
  • fluvoxamine
    • May
    • Increase
    • Ssri
    • Serotonin
    • Ssris
    • Cyp1a2
    • Effective
    • Mg
    • Reuptake
    • Treatment
    • Metabolized
    • Cyp2d6
  • major depressive disorder
    • Social
    • Anxiety
    • Major
    • Also
    • Approved
    • Ocd
    • Ssri
    • Common
    • Cyp3a4
    • Drug
    • Others
    • Treatment
  • obsessive–compulsive disorder
    • Social
    • Anxiety
    • Major
    • Also
    • Approved
    • Ocd
    • Ssri
    • Drug
    • Treatment
    • Common
    • Cyp3a4
    • Inhibitor
  • anxiety disorders
    • Social
    • Disorder
    • Ocd
    • Approved
    • Common
    • Major
    • Effective
    • Including
    • Sexual
    • Effects
    • Treatment
    • Ssris
  • panic disorder
    • Social
    • Anxiety
    • Major
    • Also
    • Approved
    • Ocd
    • Ssri
    • Drug
    • Treatment
    • Common
    • Cyp3a4
    • Inhibitor
  • social anxiety disorder
    • Social
    • Anxiety
    • Disorder
    • Major
    • Also
    • Ocd
    • Approved
    • Ssri
    • Common
    • Effective
    • Including
    • Drug
  • post-traumatic stress disorder
    • Social
    • Anxiety
    • Major
    • Also
    • Approved
    • Ocd
    • Ssri
    • Drug
    • Treatment
    • Common
    • Cyp3a4
    • Inhibitor

Connections between topic areas Semantic bridges

For Fluvoxamine, one of the stronger structural bridges in this analysis connects Fluvoxamine with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Fluvoxamine — Interactions · splits 95 ⟂ 65
Fluvoxamine — Adverse effects · splits 123 ⟂ 37
Fluvoxamine — Overview · splits 138 ⟂ 22
Fluvoxamine — Pharmacology · splits 147 ⟂ 13
Fluvoxamine — Medical uses · splits 149 ⟂ 11
Fluvoxamine — History · splits 153 ⟂ 7

Map overview Semantic statistics

Fluvoxamine

Nodes160
Edges159
Triples119
Avg. degree1.99
Density0.0125
Components1

Source & methodology

TTTA analyzes the structure around Fluvoxamine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications, Research & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Fluvoxamine · EN edition · Analysis: TopicsToTalkAbout

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