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Paroxetine: Community, Culture, Applications & Research

Paroxetine, sold under the brand name Paxil among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class used to treat major depressive disorder, obsessive–compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), generalized anxiety disorder, and premenstrual…

Language: English [EN]
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Paroxetine topic overview

The analysis highlights Community, Culture, Applications and Research as prominent areas in the source structure around Paroxetine.

Related topics
115
Source areas
9
Connected nodes
124
Extracted relationships
145
Concept neighborhoods
31
Bridge connections
124

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 27 topics
Overview · 23 topics
Interactions · 16 topics
Other organisms · 14 topics
Research · 8 topics
Society and culture · 8 topics
Pharmacology · 7 topics
Medical uses · 6 topics
Overdose · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N06AB05 (WHO)
Bioavailability
50%
CAS Number
61869-08-7 Y
ChEBI
CHEBI:7936 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Overdose

Interactions

Pharmacology

Society and culture

Research

Other organisms

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Paroxetine connects Entity context

The extracted context around Paroxetine shows recurring relationship patterns in the source. For example, Paroxetine → Common, FAA, FAA Authorization, SC, Serious, SI, SNRIs, Special Consideration, Special Issuance, SSRIs, The Federal Aviation Administration, Use, While Another extracted example is Paroxetine → Another, Common, FDA, Glaxo, GSK, In, International Federation, Many, Pharmaceutical Manufacturers Associations, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Paroxetine

Top relations

has effect · 13
Paroxetine → Common, FAA, FAA Authorization, SC, Serious, SI, SNRIs, Special Consideration, Special Issuance, SSRIs, The Federal Aviation Administration, Use, While
related to Discontinuation syndrome · 10
Paroxetine → Another, Common, FDA, Glaxo, GSK, In, International Federation, Many, Pharmaceutical Manufacturers Associations, The
related to Marketing · 10
Paroxetine → GlaxoSmithKline, GSK, GSK's, In, It, Justice, One, Paxil, The, United States Department
related to Post-SSRI sexual dysfunction · 9
Paroxetine → Characteristic, In, PSSD, Severe, SSRI, SSRIs, The, The DSM-5, While
related to Interactions · 8
Paroxetine → Interactions, MAO, MAOI, NMS, SNRIs, SSRIs, Such, The
related to Pregnancy · 7
Paroxetine → Antidepressant, Apgar, Babies, Gynecologists, Obstetricians, The American College, Unless
Legal status · 6
Paroxetine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Society and culture · 6
Paroxetine → Essential Medicines, GlaxoSmithKline, In, It, United States, World Health Organization's List
related to Overdose · 5
Paroxetine → Acute, Along, Plasma, Postmortem, SSRIs
related to Suicide · 5
Paroxetine → In, Like, Study, The BMJ, The FDA

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

may treatment effects also sexual dysfunction serotonin ssris disorder states use inhibitor united anxiety risk used side include discontinuation syndrome

Paroxetine relationships Subject–Predicate–Object triples

TTTA extracted 145 structured relationships around Paroxetine. Examples in this analysis include Paroxetine → 3D model (JSmol) → Interactive image and Paroxetine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Paroxetine3D model (JSmol)Interactive image1.00infobox
ParoxetineAHFS/Drugs.comMonograph1.00infobox
ParoxetineATC codeN06AB05 (WHO)1.00infobox
ParoxetineBioavailability50%1.00infobox
ParoxetineCAS Number61869-08-7 Y1.00infobox
ParoxetineChEBICHEBI:7936 N1.00infobox
ParoxetineChEMBLChEMBL490 Y1.00infobox
ParoxetineChemSpider39888 Y1.00infobox
ParoxetineCompTox Dashboard (EPA)DTXSID30234251.00infobox
ParoxetineDrug classSelective serotonin reuptake inhibitor (SSRI)1.00infobox
ParoxetineDrugBankDB00715 Y1.00infobox
ParoxetineECHA InfoCard100.112.0961.00infobox
ParoxetineElimination half-life21 hours1.00infobox
ParoxetineExcretionKidney (64%; 2% unchanged and 62% as metabolites), faecal (36%; <1% unchanged)1.00infobox
ParoxetineFormulaC19H20FNO31.00infobox
ParoxetineIUPHAR/BPS47901.00infobox
ParoxetineKEGGD02362 Y1.00infobox
ParoxetineLegal statusAU: S4 (Prescription only)1.00infobox
ParoxetineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
ParoxetineLegal statusCA: ℞-only1.00infobox
ParoxetineLegal statusUK: POM (Prescription only)1.00infobox
ParoxetineLegal statusUS: ℞-only1.00infobox
ParoxetineLegal statusIn general: ℞ (Prescription only)1.00infobox
ParoxetineLicense dataUS DailyMed: Paroxetine1.00infobox
ParoxetineMedlinePlusa6980321.00infobox
ParoxetineMetabolismExtensive, liver (mostly CYP2D6-mediated)1.00infobox
ParoxetineMolar mass329.371 g·mol−11.00infobox
ParoxetinePregnancy categoryAU: D1.00infobox
ParoxetinePronunciation/pərˈɑːksəˌtin/ pər-AHK-sə-TEEN1.00infobox
ParoxetineProtein binding93–95%1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Paroxetine bring nearby vocabulary together. In this analysis, examples include Treatment, Associated and Disorder. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Paroxetine
    • Treatment
    • Associated
    • Disorder
    • Ssris
    • Depression
    • May
    • Anxiety
    • Including
    • Placebo
    • Used
    • Risk
    • States
  • paroxetine
    • Treatment
    • Associated
    • Disorder
    • Ssris
    • Depression
    • May
    • Anxiety
    • Including
    • Placebo
    • Used
    • Risk
    • States
  • selective serotonin reuptake inhibitor
    • Serotonin
    • Syndrome
    • Reuptake
    • May
    • Used
    • Administration
    • Effects
    • Include
    • Side
    • Anxiety
    • Dysfunction
    • Sexual
  • major depressive disorder
    • Anxiety
    • Used
    • Also
    • Treatment
    • Flashes
    • Hot
    • Reuptake
    • Depression
    • Paroxetine
    • May
    • Serotonin
    • Inhibitor
  • obsessive–compulsive disorder
    • Anxiety
    • Used
    • Also
    • Treatment
    • Flashes
    • Hot
    • Reuptake
    • Depression
    • Paroxetine
    • May
    • Serotonin
    • Inhibitor
  • panic disorder
    • Anxiety
    • Used
    • Also
    • Treatment
    • Flashes
    • Hot
    • Reuptake
    • Depression
    • Paroxetine
    • May
    • Serotonin
    • Inhibitor
  • social anxiety disorder
    • Anxiety
    • Disorder
    • Depression
    • Used
    • Also
    • Flashes
    • Hot
    • Reuptake
    • Treatment
    • Serotonin
    • Inhibitor
    • Use
  • post-traumatic stress disorder
    • Anxiety
    • Used
    • Also
    • Treatment
    • Flashes
    • Hot
    • Reuptake
    • Depression
    • Paroxetine
    • May
    • Serotonin
    • Inhibitor

Connections between topic areas Semantic bridges

For Paroxetine, one of the stronger structural bridges in this analysis connects Paroxetine with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Paroxetine — Adverse effects · splits 97 ⟂ 28
Paroxetine — Overview · splits 101 ⟂ 24
Paroxetine — Interactions · splits 108 ⟂ 17
Paroxetine — Other organisms · splits 110 ⟂ 15
Paroxetine — Society and culture · splits 116 ⟂ 9
Paroxetine — Research · splits 116 ⟂ 9
Paroxetine — Pharmacology · splits 117 ⟂ 8
Paroxetine — Medical uses · splits 118 ⟂ 7
Paroxetine — Overdose · splits 118 ⟂ 7

Map overview Semantic statistics

Paroxetine

Nodes125
Edges124
Triples145
Avg. degree1.98
Density0.016
Components1

Source & methodology

TTTA analyzes the structure around Paroxetine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Community, Culture, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Paroxetine · EN edition · Analysis: TopicsToTalkAbout

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