Ibuprofen

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Ibuprofen topic overview

The analysis highlights History, Applications, Research and Art as prominent areas in the source structure around Ibuprofen.

Related topics: 187
Source areas: 8
Connected nodes: 195
Extracted relationships: 150
Related term clusters: 38
Bridge connections: 195

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 47 topics

Chemistry · 40 topics

Overview · 38 topics

Research · 24 topics

Pharmacology · 18 topics

Medical uses · 12 topics

Availability and administration · 4 topics

History · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol): Interactive image
AHFS/Drugs.com: Monograph
ATC code: C01EB16 (WHO) G02CC01 (WHO) M01AE01 (WHO) M02AA13 (WHO) R02AX02 (WHO)
Bioavailability: 80–100% (oral), 87% (rectal)
Boiling point: 157 °C (315 °F) at 4 mmHg
CAS Number: 15687-27-1 Y

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Ibuprofen

9Nonsteroidal anti-inflammatory drug · Pain · Fever

8Profen (drug class) · Ketoprofen · Flurbiprofen

4Acne · Anti-inflammatory · Orthostatic hypotension

14Side effect · Heartburn · Nausea

12Nottingham · Stewart Adams (chemist) · Boots (company)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Medical uses

Pharmacology

History

Availability and administration

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Ibuprofen connects Entity context

The extracted context around Ibuprofen shows recurring relationship patterns in the source. For example, Ibuprofen → Adams, Boots, Boots Group, Boots's, Later, NSAID, OTC, Queen's Award, Stewart Adams, Technical Achievement, United Kingdom, United States Another extracted example is Ibuprofen → AAN, Advil, Australian Approved Name, BAN, British Approved Name, INN, Motrin, United Kingdom, United States, United States Adopted Name, USAN. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to history · 12

Ibuprofen → Adams, Boots, Boots Group, Boots's, Later, NSAID, OTC, Queen's Award, Stewart Adams, Technical Achievement, United Kingdom, United States

related to Availability and administration · 11

Ibuprofen → AAN, Advil, Australian Approved Name, BAN, British Approved Name, INN, Motrin, United Kingdom, United States, United States Adopted Name, USAN

related to Pharmacology · 10

Ibuprofen → A2, Antipyretic, COX, COX-1, COX-2, H2, Inhibition, Like, NSAIDs, PGH2

related to Research · 9

Ibuprofen → Alzheimer's, Aspirin, Harvard Medical School, In March, Japan, NSAIDs, Parkinson's, People, Use

related to Cardiovascular risk · 7

Ibuprofen → Along, EMA, FDA, July, NSAID, NSAIDs, The European Medicines Agency

related to Chemistry · 6

Ibuprofen → Boots Group, Darzens, EtOH, Firstly, Friedel-Crafts, Later

related to Overdose · 6

Ibuprofen → Generally, Human, Many, NSAIDs, OTC, Rarely

related to Skin · 6

Ibuprofen → Along, Johnson, Like, NSAIDs, SJS, Stevens

Legal status · 5

Ibuprofen → AU: OTC, CA: OTC, EU: OTC, UK: General sales list (GSL, OTC), US: OTC / Rx-only

is a · 5

Ibuprofen → extremely rare cause of the autoimmune diseases Stevens, international nonproprietary name, nonselective COX inhibitor, nonsteroidal anti-inflammatory drug, weaker anti-inflammatory agent than other NSAIDs.Ibuprofen was discovered in 1961 in Nottingham by Stewart Adams and John Nicholson while working at Boots the Chemists

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nsaids aspirin risk pain effects drug may anti-inflammatory used united states treatment include paracetamol blood including heart overdose nsaid symptoms

Ibuprofen relationships Subject–Predicate–Object triples

TTTA extracted 150 structured relationships around Ibuprofen. Examples in this analysis include Ibuprofen → 3D model (JSmol) → Interactive image and Ibuprofen → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Ibuprofen	3D model (JSmol)	Interactive image	1.00	infobox
Ibuprofen	AHFS/Drugs.com	Monograph	1.00	infobox
Ibuprofen	ATC code	C01EB16 (WHO) G02CC01 (WHO) M01AE01 (WHO) M02AA13 (WHO) R02AX02 (WHO)	1.00	infobox
Ibuprofen	Bioavailability	80–100% (oral), 87% (rectal)	1.00	infobox
Ibuprofen	Boiling point	157 °C (315 °F) at 4 mmHg	1.00	infobox
Ibuprofen	CAS Number	15687-27-1 Y	1.00	infobox
Ibuprofen	ChEBI	CHEBI:5855 Y	1.00	infobox
Ibuprofen	ChEMBL	ChEMBL521 Y	1.00	infobox
Ibuprofen	ChemSpider	3544 Y	1.00	infobox
Ibuprofen	Chirality	Racemic mixture	1.00	infobox
Ibuprofen	CompTox Dashboard (EPA)	DTXSID5020732	1.00	infobox
Ibuprofen	Density	1.03 g/cm3	1.00	infobox
Ibuprofen	Drug class	Nonsteroidal anti-inflammatory drug (NSAID)	1.00	infobox
Ibuprofen	DrugBank	DB01050 Y	1.00	infobox
Ibuprofen	ECHA InfoCard	100.036.152	1.00	infobox
Ibuprofen	Elimination half-life	2–4 hours	1.00	infobox
Ibuprofen	Excretion	Urine (95%)	1.00	infobox
Ibuprofen	Formula	C13H18O2	1.00	infobox
Ibuprofen	IUPHAR/BPS	2713	1.00	infobox
Ibuprofen	KEGG	D00126 Y	1.00	infobox
Ibuprofen	Legal status	AU: OTC	1.00	infobox
Ibuprofen	Legal status	CA: OTC	1.00	infobox
Ibuprofen	Legal status	UK: General sales list (GSL, OTC)	1.00	infobox
Ibuprofen	Legal status	US: OTC / Rx-only	1.00	infobox
Ibuprofen	Legal status	EU: OTC	1.00	infobox
Ibuprofen	License data	US DailyMed: Ibuprofen	1.00	infobox
Ibuprofen	MedlinePlus	a682159	1.00	infobox
Ibuprofen	Melting point	75 to 78 °C (167 to 172 °F)	1.00	infobox
Ibuprofen	Metabolism	Liver (CYP2C9)	1.00	infobox
Ibuprofen	Metabolites	Ibuprofen glucuronide, 2-hydroxyibuprofen, 3-hydroxyibuprofen, carboxy-ibuprofen, 1-hydroxyibuprofen	1.00	infobox

Related concept clusters Related term clusters

The concept neighborhoods around Ibuprofen bring nearby vocabulary together. In this analysis, examples include Nsaids, Aspirin and Risk. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Ibuprofen
- Nsaids
- Aspirin
- Risk
- Overdose
- Used
- Use
- States
- United
- Pain
- May
- Lysine
- Medical
ibuprofen
- Nsaids
- Aspirin
- Risk
- Overdose
- Used
- Use
- States
- United
- Pain
- May
- Lysine
- Medical
pain
- Used
- Adams
- Medical
- Research
- Boots
- Paracetamol
- People
- Include
- Effects
- Aspirin
- Risk
- Pregnancy
abdominal pain
- Used
- Adams
- Medical
- Research
- Boots
- Paracetamol
- People
- Include
- Effects
- Aspirin
- Risk
- Pregnancy
pain from kidney stones
- Heart
- Administration
- Low
- Nsaid
- Used
- Blood
- Adams
- Medical
- Research
- Boots
- Paracetamol
- People
lower back pain
- Used
- Adams
- Medical
- Research
- Boots
- Paracetamol
- People
- Include
- Effects
- Aspirin
- Risk
- Pregnancy
nonsteroidal anti-inflammatory drug
- Fever
- Administration
- Pain
- Used
- Nsaid
- Drug
- Lysine
- Nsaids
- Adams
- Medical
- Boots
- Kidney
side effects
- Include
- Blood
- Kidney
- Overdose
- Pain
- Risk
- Pregnancy
- Administration
- Fever
- Lysine
- Medical
- Research

Connections between topic areas Semantic bridges

For Ibuprofen, one of the stronger structural bridges in this analysis connects Ibuprofen with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Ibuprofen — Adverse effects · splits 148 ⟂ 48

Ibuprofen — Chemistry · splits 155 ⟂ 41

Ibuprofen — Overview · splits 157 ⟂ 39

Ibuprofen — Research · splits 171 ⟂ 25

Ibuprofen — Pharmacology · splits 177 ⟂ 19

Ibuprofen — Medical uses · splits 183 ⟂ 13

Ibuprofen — History · splits 191 ⟂ 5

Ibuprofen — Availability and administration · splits 191 ⟂ 5

Map overview Semantic statistics

Ibuprofen

Nodes196

Edges195

Triples150

Avg. degree1.99

Density0.010204

Components1

Source & methodology

TTTA analyzes the structure around Ibuprofen to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications, Research & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ibuprofen · EN edition · Analysis: TopicsToTalkAbout

Ibuprofen: History, Applications, Research & Art

Ibuprofen topic overview

What this topic covers Research coverage

Key facts & relationships

Start with your topic. Discover where to go next.

Questions to explore

Explore all related topics Closing gaps

Overview

Medical uses

Adverse effects

Pharmacology

Chemistry

History

Availability and administration

Research

For the semantics nerds

Advanced semantic analysis

How Ibuprofen connects Entity context

Ibuprofen

Top relations

Important terminology

Important terminology

Ibuprofen relationships Subject–Predicate–Object triples

Related concept clusters Related term clusters

Connections between topic areas Semantic bridges

Map overview Semantic statistics

Ibuprofen

Source & methodology