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Ibuprofen

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis. It can be taken orally (by mouth) or intravenously (injected into a vein). It typically begins working within an hour.

History, Applications, Research & Art

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C01EB16 (WHO) G02CC01 (WHO) M01AE01 (WHO) M02AA13 (WHO) R02AX02 (WHO)
Bioavailability
80–100% (oral), 87% (rectal)
Boiling point
157 °C (315 °F) at 4 mmHg
CAS Number
15687-27-1 Y

Topics to explore

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Overview

Medical uses

Adverse effects

Pharmacology

Chemistry

History

Availability and administration

Research

Advanced semantic analysis

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Map overview Semantic statistics

Ibuprofen

Nodes196
Edges195
Triples188
Avg. degree1.99
Density0.010204
Components1

How this topic connects Entity context

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Ibuprofen

Top relations

related to External links · 15
Ibuprofen → Anti-Inflammatory Agents, August, Boots Pure Drug Co, Evidence, GBpatent, John Stuart Nicholson, Lowe, Ltd, National Safety Council, NSC, PDF, Science, September, Stewart Sanders Adams, The Ibuprofen Revolution
related to history · 15
Ibuprofen → Adams, Boots, Boots Group, Boots's, In, Its, Later, NSAID, OTC, Queen's Award, Stewart Adams, Technical Achievement, The, United Kingdom, United States
related to Availability and administration · 12
Ibuprofen → AAN, Advil, Australian Approved Name, BAN, British Approved Name, In, INN, Motrin, United Kingdom, United States, United States Adopted Name, USAN
related to Pharmacology · 12
Ibuprofen → A2, Antipyretic, COX, COX-1, COX-2, H2, However, Inhibition, Like, NSAIDs, PGH2, The
related to Research · 10
Ibuprofen → Alzheimer's, As, Aspirin, Harvard Medical School, In March, Japan, NSAIDs, Parkinson's, People, Use
related to Cardiovascular risk · 8
Ibuprofen → Along, EMA, FDA, July, NSAID, NSAIDs, On, The European Medicines Agency
related to Chemistry · 8
Ibuprofen → Boots Group, Darzens, EtOH, Firstly, Friedel-Crafts, Later, The, Then
related to Overdose · 8
Ibuprofen → Generally, Human, Many, Most, NSAIDs, OTC, Rarely, The
related to Skin · 7
Ibuprofen → Along, As, Johnson, Like, NSAIDs, SJS, Stevens
related to Ibuprofen lysine · 6
Ibuprofen → Drug Administration, FDA, Food, However, In, United States

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nsaids aspirin risk pain effects drug may anti-inflammatory used however united states treatment include paracetamol blood including heart overdose nsaid

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ibuprofen3D model (JSmol)Interactive image1.00infobox
IbuprofenAHFS/Drugs.comMonograph1.00infobox
IbuprofenATC codeC01EB16 (WHO) G02CC01 (WHO) M01AE01 (WHO) M02AA13 (WHO) R02AX02 (WHO)1.00infobox
IbuprofenBioavailability80–100% (oral), 87% (rectal)1.00infobox
IbuprofenBoiling point157 °C (315 °F) at 4 mmHg1.00infobox
IbuprofenCAS Number15687-27-1 Y1.00infobox
IbuprofenChEBICHEBI:5855 Y1.00infobox
IbuprofenChEMBLChEMBL521 Y1.00infobox
IbuprofenChemSpider3544 Y1.00infobox
IbuprofenChiralityRacemic mixture1.00infobox
IbuprofenCompTox Dashboard (EPA)DTXSID50207321.00infobox
IbuprofenDensity1.03 g/cm31.00infobox
IbuprofenDrug classNonsteroidal anti-inflammatory drug (NSAID)1.00infobox
IbuprofenDrugBankDB01050 Y1.00infobox
IbuprofenECHA InfoCard100.036.1521.00infobox
IbuprofenElimination half-life2–4 hours1.00infobox
IbuprofenExcretionUrine (95%)1.00infobox
IbuprofenFormulaC13H18O21.00infobox
IbuprofenIUPHAR/BPS27131.00infobox
IbuprofenKEGGD00126 Y1.00infobox
IbuprofenLegal statusAU: OTC1.00infobox
IbuprofenLegal statusCA: OTC1.00infobox
IbuprofenLegal statusUK: General sales list (GSL, OTC)1.00infobox
IbuprofenLegal statusUS: OTC / Rx-only1.00infobox
IbuprofenLegal statusEU: OTC1.00infobox
IbuprofenLicense dataUS DailyMed: Ibuprofen1.00infobox
IbuprofenMedlinePlusa6821591.00infobox
IbuprofenMelting point75 to 78 °C (167 to 172 °F)1.00infobox
IbuprofenMetabolismLiver (CYP2C9)1.00infobox
IbuprofenMetabolitesIbuprofen glucuronide, 2-hydroxyibuprofen, 3-hydroxyibuprofen, carboxy-ibuprofen, 1-hydroxyibuprofen1.00infobox

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