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Diazepam

Diazepam, sold under the brand name Valium among others, is a medication of the benzodiazepine family that acts as an anxiolytic. It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. It may also be used to cause memory loss during certain medical…

History, Community, Culture & Applications

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Key facts & relationships

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3D model (JSmol)
Interactive image
Addiction liability
Moderate
AHFS/Drugs.com
Monograph
ATC code
N05BA01 (WHO)
Bioavailability
Oral: 76% (64–97%) Rectal: 81% (62–98%)
CAS Number
439-14-5 Y

Topics to explore

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Overview

Medical uses

Contraindications

Adverse effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Diazepam

Nodes283
Edges282
Triples202
Avg. degree1.99
Density0.007067
Components1

How this topic connects Entity context

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Diazepam

Top relations

related to Chemistry · 14
Diazepam → CD, LogP, M'-conformer, Molecules, MW, Octanol-Water Partition Coefficient, P'-conformer, PSA, The, The LogP, The TPSA, This, Topological Polar Surface Area, TPSA
has effect · 13
Diazepam → Additionally, Benzodiazepines, Drug, Drug Administration, FDA, Food, In September, Infusions, Like, Long-term, Sedatives, Short-term, The
related to Abuse and special populations · 13
Diazepam → Benzodiazepine, Benzodiazepines, Concomitant, Doses, Elderly, Floppy, Intravenous, Long-acting, Pediatric, Symptoms, The, Under, Use
related to Further reading · 13
Diazepam → Biotechnology Information, Bookshelf ID, CYP2C19 Genotype, Dean, Diazepam Therapy, In Pratt VM, McLeod HL, Medical Genetics Summaries, National Center, NBK379740, NCBI, PMID, Rubinstein WS
related to history · 12
Diazepam → After, Benzodiazepine, Hoffmann-La Roche, It, Leo Sternbach, Librium, Medical, New Jersey, Nutley, Released, Roche, The
Legal status · 10
Diazepam → AU: S4 (Prescription only), BR: Class B1 (Psychoactive drugs), CA: Schedule IV, DE: Prescription only (Anlage III for higher doses), EU: Rx-only, NZ: Class C5, SE: Förteckning IV, UK: Class C, UN: Psychotropic Schedule IV, US: Schedule IV
related to Availability · 10
Diazepam → Both, CANA, Convulsive Antidote, It, Mark, NAAK, Nerve Agent, One CANA, The United States, They
related to Mechanism of action · 9
Diazepam → As, Benzodiazepines, Drugs, For, GABA, GABAA, The, The GABAA, This
related to Synthesis · 7
Diazepam → Although, Hoffmann-La Roche, Leo Sternbach, Nordazepam, Sternbach's, The, This
related to Contraindications · 5
Diazepam → AtaxiaSevere, History, Liver, Severe, Use

Important terminology Word statistics

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Important terminology

benzodiazepines may effects benzodiazepine used drug withdrawal alcohol use also dependence tolerance symptoms drugs seizures dose treatment including risk muscle

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Diazepam3D model (JSmol)Interactive image1.00infobox
DiazepamAddiction liabilityModerate1.00infobox
DiazepamAHFS/Drugs.comMonograph1.00infobox
DiazepamATC codeN05BA01 (WHO)1.00infobox
DiazepamBioavailabilityOral: 76% (64–97%) Rectal: 81% (62–98%)1.00infobox
DiazepamCAS Number439-14-5 Y1.00infobox
DiazepamChEBICHEBI:49575 Y1.00infobox
DiazepamChEMBLChEMBL12 Y1.00infobox
DiazepamChemSpider2908 Y1.00infobox
DiazepamCompTox Dashboard (EPA)DTXSID40204061.00infobox
DiazepamDependence liabilityHigh1.00infobox
DiazepamDrug classBenzodiazepine1.00infobox
DiazepamDrugBankDB00829 N1.00infobox
DiazepamECHA InfoCard100.006.4761.00infobox
DiazepamElimination half-life(50 h); 20–100 h (32–200 h for main active metabolite desmethyldiazepam)1.00infobox
DiazepamExcretionKidney1.00infobox
DiazepamFormulaC16H13ClN2O1.00infobox
DiazepamIUPHAR/BPS33641.00infobox
DiazepamKEGGD00293 Y1.00infobox
DiazepamLegal statusAU: S4 (Prescription only)1.00infobox
DiazepamLegal statusBR: Class B1 (Psychoactive drugs)1.00infobox
DiazepamLegal statusCA: Schedule IV1.00infobox
DiazepamLegal statusDE: Prescription only (Anlage III for higher doses)1.00infobox
DiazepamLegal statusNZ: Class C51.00infobox
DiazepamLegal statusUK: Class C1.00infobox
DiazepamLegal statusUS: Schedule IV1.00infobox
DiazepamLegal statusUN: Psychotropic Schedule IV1.00infobox
DiazepamLegal statusEU: Rx-only1.00infobox
DiazepamLegal statusSE: Förteckning IV1.00infobox
DiazepamLicense dataUS DailyMed: Diazepam1.00infobox

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