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Verapamil: Applications & Art

Verapamil, sold under various trade names, is a calcium channel blocker medication used for the treatment of high blood pressure, angina (chest pain from not enough blood flow to the heart), and supraventricular tachycardia. It may also be used for the prevention of migraines and cluster headaches. It is given by mouth or by injection into a vein.

Language: English [EN]
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Verapamil topic overview

The analysis highlights Applications and Art as prominent areas in the source structure around Verapamil.

Related topics
96
Source areas
7
Connected nodes
103
Extracted relationships
87
Concept neighborhoods
38
Bridge connections
103

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Medical uses · 22 topics
Side effects · 19 topics
Overview · 18 topics
Mechanism of action · 13 topics
Uses in cell biology · 13 topics
Contraindications · 7 topics
Pharmacokinetic details · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C08DA01 (WHO)
Bioavailability
35.1%
CAS Number
52-53-9 Y
ChEBI
CHEBI:9948 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Side effects

Mechanism of action

Pharmacokinetic details

Uses in cell biology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Verapamil connects Entity context

The extracted context around Verapamil shows recurring relationship patterns in the source. For example, Verapamil → As, Because, Biphasic, It, IV, L/kg, More, Onset, Plasma, This Another extracted example is Verapamil → ABC, ATP-binding, CSC, DNA, DNA-binding, Hoechst, It, P-glycoprotein, Radioactively, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Verapamil

Top relations

related to Pharmacokinetic details · 10
Verapamil → As, Because, Biphasic, It, IV, L/kg, More, Onset, Plasma, This
related to Uses in cell biology · 10
Verapamil → ABC, ATP-binding, CSC, DNA, DNA-binding, Hoechst, It, P-glycoprotein, Radioactively, This
related to Mechanism of action · 7
Verapamil → AV, In, IV, Kv, Since, Specific, Verapamil's
Legal status · 4
Verapamil → EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
has effect · 4
Verapamil → Along, Other, The, While
related to Contraindications · 4
Verapamil → Hg, It, Use, Wolff-Parkinson-White
related to Cluster headaches · 3
Verapamil → CGRP-release, CGRPs, Preventive
related to Medical uses · 3
Verapamil → Prinzmetal, PSVT, SVT
related to Overdose · 3
Verapamil → Acute, Blood, Plasma
KEGG · 2
Verapamil → as HCl: D00619 Y, D02356 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

used calcium blood channel also heart use side pressure cell effects blocker angina plasma may rate include medication medical drug

Verapamil relationships Subject–Predicate–Object triples

TTTA extracted 87 structured relationships around Verapamil. Examples in this analysis include Verapamil → 3D model (JSmol) → Interactive image and Verapamil → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Verapamil3D model (JSmol)Interactive image1.00infobox
VerapamilAHFS/Drugs.comMonograph1.00infobox
VerapamilATC codeC08DA01 (WHO)1.00infobox
VerapamilBioavailability35.1%1.00infobox
VerapamilCAS Number52-53-9 Y1.00infobox
VerapamilChEBICHEBI:9948 Y1.00infobox
VerapamilChEMBLChEMBL6966 Y1.00infobox
VerapamilChemSpider2425 Y1.00infobox
VerapamilChiralityRacemic mixture1.00infobox
VerapamilCompTox Dashboard (EPA)DTXSID90411521.00infobox
VerapamilDrug classCalcium channel blocker1.00infobox
VerapamilDrugBankDB00661 Y1.00infobox
VerapamilECHA InfoCard100.000.1331.00infobox
VerapamilElimination half-life2.8–7.4 hours1.00infobox
VerapamilExcretionKidney: 11%1.00infobox
VerapamilFormulaC27H38N2O41.00infobox
VerapamilIUPHAR/BPS24061.00infobox
VerapamilKEGGD02356 Y1.00infobox
VerapamilKEGGas HCl: D00619 Y1.00infobox
VerapamilLegal statusUK: POM (Prescription only)1.00infobox
VerapamilLegal statusUS: ℞-only1.00infobox
VerapamilLegal statusEU: Rx-only1.00infobox
VerapamilLegal statusIn general: ℞ (Prescription only)1.00infobox
VerapamilLicense dataUS DailyMed: Verapamil1.00infobox
VerapamilMedlinePlusa6840301.00infobox
VerapamilMetabolismLiver1.00infobox
VerapamilMolar mass454.611 g·mol−11.00infobox
VerapamilOnset of action1 to 2 hours (oral); 3 to 5 minutes (IV bolus)1.00infobox
VerapamilPregnancy categoryAU: C1.00infobox
VerapamilPronunciation/vɛˈræpəmɪl/ ve-RAP-ə-mil1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Verapamil bring nearby vocabulary together. In this analysis, examples include Use, Used and Channel. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Verapamil
    • Use
    • Used
    • Channel
    • Blood
    • Calcium
    • Medical
    • Treatment
    • Effect
    • Cell
    • Blocker
    • Onset
    • Supraventricular
  • verapamil
    • Use
    • Used
    • Channel
    • Blood
    • Calcium
    • Medical
    • Treatment
    • Effect
    • Cell
    • Blocker
    • Onset
    • Supraventricular
  • calcium channel blocker
    • Channel
    • Blocker
    • Blockers
    • Supraventricular
    • Tachycardia
    • Calcium
    • Blood
    • Action
    • Cluster
    • Headache
    • Headaches
    • Mechanism
  • high blood pressure
    • Pressure
    • Nausea
    • Low
    • Headache
    • Angina
    • Include
    • Calcium
    • Effects
    • Heart
    • Side
    • Channel
    • Use
  • low blood pressure
    • Nausea
    • Pressure
    • Low
    • Side
    • Headache
    • Rate
    • Angina
    • Include
    • Calcium
    • Effects
    • Heart
    • Channel
  • non–dihydropyridine calcium channel blocker
    • Channel
    • Blocker
    • Blockers
    • Supraventricular
    • Tachycardia
    • Calcium
    • Blood
    • Action
    • Cluster
    • Headache
    • Headaches
    • Mechanism
  • blood pressure
    • Pressure
    • Nausea
    • Low
    • Headache
    • Angina
    • Include
    • Calcium
    • Effects
    • Heart
    • Side
    • Channel
    • Use
  • voltage-dependent calcium channels
    • Channel
    • Blockers
    • Blocker
    • Blood
    • Mechanism
    • Supraventricular
    • Tachycardia
    • Used
    • Verapamil
    • Heart
    • Action
    • Cluster

Connections between topic areas Semantic bridges

For Verapamil, one of the stronger structural bridges in this analysis connects Verapamil with Medical uses. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Verapamil — Medical uses · splits 81 ⟂ 23
Verapamil — Side effects · splits 84 ⟂ 20
Verapamil — Overview · splits 85 ⟂ 19
Verapamil — Mechanism of action · splits 90 ⟂ 14
Verapamil — Uses in cell biology · splits 90 ⟂ 14
Verapamil — Contraindications · splits 96 ⟂ 8
Verapamil — Pharmacokinetic details · splits 99 ⟂ 5

Map overview Semantic statistics

Verapamil

Nodes104
Edges103
Triples87
Avg. degree1.98
Density0.019231
Components1

Source & methodology

TTTA analyzes the structure around Verapamil to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Verapamil · EN edition · Analysis: TopicsToTalkAbout

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