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Omeprazole: History, Applications & Standards

Omeprazole, sold under the brand names Prilosec and Losec among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton-pump inhibitor (PPI) and its…

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Omeprazole topic overview

The analysis highlights History, Applications and Standards as prominent areas in the source structure around Omeprazole.

Related topics
111
Source areas
8
Connected nodes
119
Extracted relationships
130
Concept neighborhoods
22
Bridge connections
119

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 37 topics
Overview · 30 topics
Interactions · 18 topics
Medical uses · 8 topics
History · 7 topics
Pharmacology · 6 topics
Chemistry · 3 topics
Veterinary uses · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A02BC01 (WHO) A02BC51 (WHO)
Bioavailability
35–76%
CAS Number
73590-58-6 Y
ChEBI
CHEBI:7772 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Interactions

Pharmacology

Chemistry

History

Veterinary uses

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Omeprazole connects Entity context

The extracted context around Omeprazole shows recurring relationship patterns in the source. For example, Omeprazole → Astra AB, AstraZeneca, Cable Guy, Drug Administration, FDA, Gamble, In, It, Larry, Lasix, Losec, PPI, Prilosec, Prilosec OTC, Procter, Prozac, Sweden, Swedish AB Hässle, The, United States Another extracted example is Omeprazole → Biotechnology Information, Bookshelf ID, CYP2C19 Genotype, Dean, In Pratt VM, McLeod HL, Medical Genetics Summaries, National Center, NBK100895, NCBI, Omeprazole Therapy, PMID, Rubinstein WS. Use these groups to spot repeated connection types before inspecting the individual relationships.

Omeprazole

Top relations

related to history · 22
Omeprazole → Astra AB, AstraZeneca, Cable Guy, Drug Administration, FDA, Gamble, In, It, Larry, Lasix, Losec, PPI, Prilosec, Prilosec OTC, Procter, Prozac, Sweden, Swedish AB Hässle, The, United States
related to Further reading · 13
Omeprazole → Biotechnology Information, Bookshelf ID, CYP2C19 Genotype, Dean, In Pratt VM, McLeod HL, Medical Genetics Summaries, National Center, NBK100895, NCBI, Omeprazole Therapy, PMID, Rubinstein WS
related to Veterinary uses · 9
Omeprazole → April, Committee, European Medicines Agency, European Union, In February, Omeprazole TriviumVet, The, TriviumVet DAC, Veterinary Medicinal Products
related to Economics · 8
Omeprazole → Although, April, AstraZeneca, AstraZeneca's, Many, Nexium, The, When Prilosec's US
related to Interactions · 8
Omeprazole → Although, Clopidogrel, CYP2C19, CYP3A4, However, Important, Inhibition, This
related to Pharmacokinetics · 8
Omeprazole → About, CYP2C19, CYP3A4, Identified, It, L/kg, P450, The
Legal status · 5
Omeprazole → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, UK: POM (Prescription only), US: OTC / Rx-only
is a · 4
Omeprazole → inhibitor of the enzymes CYP2C19 and CYP3A4, prodrug, proton-pump inhibitor, racemate
related to Mechanism of action · 4
Omeprazole → ATPase, Because, It, The
related to Peptic ulcers · 4
Omeprazole → Amoxicillin, Helicobacter, Infection, Peptic

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cyp2c19 acid use prilosec inhibitor may also cyp3a4 drug stomach medication brand available effects losec names ppis risk pregnancy heartburn

Omeprazole relationships Subject–Predicate–Object triples

TTTA extracted 130 structured relationships around Omeprazole. Examples in this analysis include Omeprazole → 3D model (JSmol) → Interactive image and Omeprazole → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Omeprazole3D model (JSmol)Interactive image1.00infobox
OmeprazoleAHFS/Drugs.comMonograph1.00infobox
OmeprazoleATC codeA02BC01 (WHO) A02BC51 (WHO)1.00infobox
OmeprazoleBioavailability35–76%1.00infobox
OmeprazoleCAS Number73590-58-6 Y1.00infobox
OmeprazoleChEBICHEBI:7772 Y1.00infobox
OmeprazoleChEMBLChEMBL1503 Y1.00infobox
OmeprazoleChemSpider4433 Y1.00infobox
OmeprazoleChiralityRacemic mixture1.00infobox
OmeprazoleCompTox Dashboard (EPA)DTXSID60210801.00infobox
OmeprazoleDensity1.4±0.1 g/cm31.00infobox
OmeprazoleDrug classProton-pump inhibitor1.00infobox
OmeprazoleDrugBankDB00338 Y1.00infobox
OmeprazoleECHA InfoCard100.122.9671.00infobox
OmeprazoleElimination half-life1–1.2 hours1.00infobox
OmeprazoleExcretion80% (urine) 20% (bile via feces)1.00infobox
OmeprazoleFormulaC17H19N3O3S1.00infobox
OmeprazoleIUPHAR/BPS42791.00infobox
OmeprazoleKEGGD00455 Y1.00infobox
OmeprazoleLegal statusAU: S4 (Prescription only)1.00infobox
OmeprazoleLegal statusCA: ℞-only1.00infobox
OmeprazoleLegal statusUK: POM (Prescription only)1.00infobox
OmeprazoleLegal statusUS: OTC / Rx-only1.00infobox
OmeprazoleLegal statusEU: Rx-only1.00infobox
OmeprazoleLicense dataUS DailyMed: Omeprazole1.00infobox
OmeprazoleMedlinePlusa6930501.00infobox
OmeprazoleMelting point156 °C (313 °F)1.00infobox
OmeprazoleMetabolismLiver (CYP2C19, CYP3A4)1.00infobox
OmeprazoleMolar mass345.42 g·mol−11.00infobox
OmeprazolePDB ligand1C6 (PDBe, RCSB PDB)1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Omeprazole bring nearby vocabulary together. In this analysis, examples include Cyp2c19, Also and Inhibitor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Omeprazole
    • Cyp2c19
    • Also
    • Inhibitor
    • Drug
    • Acid
    • Cyp3a4
    • Use
    • Peptic
    • Used
    • System
    • Two
    • Ppis
  • omeprazole
    • Cyp2c19
    • Also
    • Inhibitor
    • Drug
    • Acid
    • Cyp3a4
    • Use
    • Peptic
    • Used
    • System
    • Two
    • Ppis
  • adverse effects
    • Include
    • Increased
    • May
    • Cyp2c19
    • Peptic
    • Pregnancy
    • Clopidogrel
    • Names
    • Treatment
    • Used
    • Heartburn
    • Metabolism
  • food and drug administration
    • Name
    • Losec
    • Prilosec
    • Omeprazole
    • Peptic
    • Pregnancy
    • Clopidogrel
    • Names
    • Treatment
    • Used
    • Astrazeneca
    • Effect
  • cyp2c19
    • Metabolism
    • Cyp3a4
    • Clopidogrel
    • Treatment
    • Effects
    • Inhibitor
    • Omeprazole
    • Peptic
    • Pregnancy
    • Names
    • Ppi
    • Used
  • proton-pump inhibitor
    • Cyp3a4
    • Ppis
    • Cyp2c19
    • Peptic
    • Pregnancy
    • Omeprazole
    • Names
    • Ppi
    • Treatment
    • Used
    • Effects
    • Heartburn
  • inhibitor
    • Cyp3a4
    • Ppis
    • Cyp2c19
    • Peptic
    • Pregnancy
    • Omeprazole
    • Names
    • Ppi
    • Treatment
    • Used
    • Effects
    • Heartburn
  • cyp3a4
    • Inhibitor
    • Metabolism
    • Peptic
    • Pregnancy
    • Names
    • Treatment
    • Used
    • Effect
    • Effects
    • Heartburn
    • Name
    • System

Connections between topic areas Semantic bridges

For Omeprazole, one of the stronger structural bridges in this analysis connects Omeprazole with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Omeprazole — Adverse effects · splits 82 ⟂ 38
Omeprazole — Overview · splits 89 ⟂ 31
Omeprazole — Interactions · splits 101 ⟂ 19
Omeprazole — Medical uses · splits 111 ⟂ 9
Omeprazole — History · splits 112 ⟂ 8
Omeprazole — Pharmacology · splits 113 ⟂ 7
Omeprazole — Chemistry · splits 116 ⟂ 4
Omeprazole — Veterinary uses · splits 117 ⟂ 3

Map overview Semantic statistics

Omeprazole

Nodes120
Edges119
Triples130
Avg. degree1.98
Density0.016667
Components1

Source & methodology

TTTA analyzes the structure around Omeprazole to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Omeprazole · EN edition · Analysis: TopicsToTalkAbout

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