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Lorazepam: History, Community, Culture & Applications

Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. It is used to treat anxiety (including anxiety disorders), insomnia, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting. It is also used during surgery to interfere with memory formation…

Language: English [EN]
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Lorazepam topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Lorazepam.

Related topics
161
Source areas
6
Connected nodes
167
Extracted relationships
218
Concept neighborhoods
32
Bridge connections
167

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 64 topics
Medical uses · 39 topics
Overview · 33 topics
Pharmacology · 10 topics
Society and culture · 8 topics
History · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
Addiction liability
Moderate
AHFS/Drugs.com
Monograph
ATC code
N05BA06 (WHO)
Bioavailability
By mouth: 85%
CAS Number
846-49-1 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Pharmacology

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Lorazepam connects Entity context

The extracted context around Lorazepam shows recurring relationship patterns in the source. For example, Lorazepam → Canada, Class, Controlled Drug, Controlled Drugs, Controlled Substances Act, Drugs Regulations, In, It, Misuse, Psychotropic Substances, Schedule, Schedule IV, Substances Act, United Kingdom, United Nations Convention, US Another extracted example is Lorazepam → Additionally, As, Benzodiazepines, Children, Comorbid, Dose, Drug, Falls, Like, Liver, Long-term, Partial, Similarly, The, Therefore. Use these groups to spot repeated connection types before inspecting the individual relationships.

Lorazepam

Top relations

related to Legal status · 16
Lorazepam → Canada, Class, Controlled Drug, Controlled Drugs, Controlled Substances Act, Drugs Regulations, In, It, Misuse, Psychotropic Substances, Schedule, Schedule IV, Substances Act, United Kingdom, United Nations Convention, US
related to Specific groups · 15
Lorazepam → Additionally, As, Benzodiazepines, Children, Comorbid, Dose, Drug, Falls, Like, Liver, Long-term, Partial, Similarly, The, Therefore
has effect · 14
Lorazepam → Adverse, Benzodiazepines, CNS, Cognitive, In, Lorazepam's, Many, Other, Paradoxical, Sedation, Sedative, Side, Using, With
related to Contraindications · 14
Lorazepam → Ataxia, Benzodiazepines, Drug Administration, FDA, Food, It, Myasthenia, Neonatal, Past, Regular, Sleep, Symptoms, The, Various
related to Pharmacokinetics · 13
Lorazepam → Although, Clinical, CNS, Diazepam, Due, However, If, On, So, The, There, Therefore, This
related to history · 9
Lorazepam → Ativan, Historically, Others, Richards, Temesta, The, United States, Wyeth Pharmaceuticals, Wyeth's
related to Pharmacodynamics · 8
Lorazepam → Benzodiazepines, GABA, GABAA, Its, Relative, The, They, Thus
related to Tolerance and dependence · 8
Lorazepam → Dependence, Due, GABAA, Higher, If, Increasing, Potent, The
Legal status · 7
Lorazepam → AU: S4 (Prescription only), BR: Class B1 (Psychoactive drugs), CA: Schedule IV, DE: Prescription only (Anlage III for higher doses), SE: Förteckning IV, UK: POM (Prescription only), US: Schedule IV
related to Recreational use · 7
Lorazepam → ER, In, Males, Of, SAMHSA, United States, US

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

effects may benzodiazepines benzodiazepine use withdrawal used people also dose diazepam anxiety adverse drug risk given sedation seizures occur doses

Lorazepam relationships Subject–Predicate–Object triples

TTTA extracted 218 structured relationships around Lorazepam. Examples in this analysis include Lorazepam → 3D model (JSmol) → Interactive image and Lorazepam → Addiction liability → Moderate. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Lorazepam3D model (JSmol)Interactive image1.00infobox
LorazepamAddiction liabilityModerate1.00infobox
LorazepamAHFS/Drugs.comMonograph1.00infobox
LorazepamATC codeN05BA06 (WHO)1.00infobox
LorazepamBioavailabilityBy mouth: 85%1.00infobox
LorazepamCAS Number846-49-1 Y1.00infobox
LorazepamChEBICHEBI:65391.00infobox
LorazepamChEMBLChEMBL580 Y1.00infobox
LorazepamChemSpider3821 Y1.00infobox
LorazepamCompTox Dashboard (EPA)DTXSID70232251.00infobox
LorazepamDependence liabilityHigh1.00infobox
LorazepamDrug classBenzodiazepine1.00infobox
LorazepamDrugBankDB00186 N1.00infobox
LorazepamDuration of actionIV/IM: 12–24 hours1.00infobox
LorazepamDuration of actionPO: 6–8 hours1.00infobox
LorazepamECHA InfoCard100.011.5341.00infobox
LorazepamElimination half-life10–20 hours1.00infobox
LorazepamExcretionKidney1.00infobox
LorazepamFormulaC15H10Cl2N2O21.00infobox
LorazepamKEGGD00365 Y1.00infobox
LorazepamLegal statusAU: S4 (Prescription only)1.00infobox
LorazepamLegal statusBR: Class B1 (Psychoactive drugs)1.00infobox
LorazepamLegal statusCA: Schedule IV1.00infobox
LorazepamLegal statusDE: Prescription only (Anlage III for higher doses)1.00infobox
LorazepamLegal statusUK: POM (Prescription only)1.00infobox
LorazepamLegal statusUS: Schedule IV1.00infobox
LorazepamLegal statusSE: Förteckning IV1.00infobox
LorazepamLicense dataUS DailyMed: Lorazepam1.00infobox
LorazepamMedlinePlusa6820531.00infobox
LorazepamMetabolismLiver glucuronidation1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Lorazepam bring nearby vocabulary together. In this analysis, examples include May, Benzodiazepines and Used. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Lorazepam
    • May
    • Benzodiazepines
    • Used
    • Use
    • Withdrawal
    • Sedation
    • Dose
    • People
    • Cause
    • Given
    • Drug
    • Intravenous
  • lorazepam
    • May
    • Benzodiazepines
    • Used
    • Use
    • Withdrawal
    • Sedation
    • Dose
    • People
    • Cause
    • Given
    • Drug
    • Intravenous
  • benzodiazepine
    • Withdrawal
    • Syndrome
    • Dependence
    • Longer
    • Use
    • Lorazepam
    • Doses
    • Treatment
    • May
    • Drug
    • Half-life
    • Tolerance
  • anxiety
    • Seizures
    • Withdrawal
    • Symptoms
    • Status
    • Alcohol
    • Doses
    • Occur
    • Sedation
    • Used
    • Use
    • Lorazepam
    • Half-life
  • anxiety disorders
    • Seizures
    • Withdrawal
    • Symptoms
    • Status
    • Alcohol
    • Doses
    • Occur
    • Sedation
    • Used
    • Use
    • Lorazepam
    • Half-life
  • seizures
    • Status
    • Intravenous
    • Used
    • Withdrawal
    • Tolerance
    • Symptoms
    • Alcohol
    • Doses
    • Elderly
    • Occur
    • Treatment
    • Sedation
  • alcohol withdrawal
    • Benzodiazepine
    • Syndrome
    • Symptoms
    • Anxiety
    • Use
    • Dependence
    • Seizures
    • Longer
    • Occur
    • People
    • Long-term
    • Drugs
  • physical dependence
    • Risk
    • Withdrawal
    • Half-life
    • Drug
    • Administration
    • Drugs
    • Syndrome
    • Doses
    • Longer
    • Adverse
    • Status
    • Use

Connections between topic areas Semantic bridges

For Lorazepam, one of the stronger structural bridges in this analysis connects Lorazepam with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
LorazepamAdverse effects · splits 103 ⟂ 65
LorazepamMedical uses · splits 128 ⟂ 40
LorazepamOverview · splits 134 ⟂ 34
LorazepamPharmacology · splits 157 ⟂ 11
LorazepamSociety and culture · splits 159 ⟂ 9
LorazepamHistory · splits 160 ⟂ 8

Map overview Semantic statistics

Lorazepam

Nodes168
Edges167
Triples218
Avg. degree1.99
Density0.011905
Components1

Source & methodology

TTTA analyzes the structure around Lorazepam to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Lorazepam · EN edition · Analysis: TopicsToTalkAbout

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