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Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive–compulsive disorder, fibromyalgia, neuropathic pain, and other types of chronic pain. It is taken by mouth.
The analysis highlights History, Applications, Research and Standards as prominent areas in the source structure around Duloxetine.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around Duloxetine shows recurring relationship patterns in the source. For example, Duloxetine → Additionally, Company, David Robertson, David Wong, Drug Administration, Eli Lilly, FDA, Good Manufacturing Practice, Indianapolis, Joseph Krushinski, Lilly, LY227942, LY248686, NDA, New Drug Application, QTc, The FDA, US Food, Use Another extracted example is Duloxetine → Australia's Therapeutic Goods Administration, Characteristic, European Medicines Agency's Pharmacovigilance, Health Canada, Post-SSRI, PRAC, PSSD, Risk Assessment Committee, SNRI, SNRIs, SSRI, SSRIs, The DSM-5. Use these groups to spot repeated connection types before inspecting the individual relationships.
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effects may treatment patients pain serotonin side fda risk sexual increased dysfunction antidepressants diabetic reuptake drug also approved neuropathic fibromyalgia
TTTA extracted 168 structured relationships around Duloxetine. Examples in this analysis include Duloxetine → 3D model (JSmol) → Interactive image and Duloxetine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Duloxetine | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Duloxetine | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Duloxetine | ATC code | N06AX21 (WHO) | 1.00 | infobox |
| Duloxetine | Bioavailability | ~50% (32–80%) | 1.00 | infobox |
| Duloxetine | CAS Number | 116539-59-4 Y | 1.00 | infobox |
| Duloxetine | CAS Number | as HCl: 136434-34-9 Y | 1.00 | infobox |
| Duloxetine | ChEBI | CHEBI:36795 Y | 1.00 | infobox |
| Duloxetine | ChEBI | as HCl: CHEBI:31526 Y | 1.00 | infobox |
| Duloxetine | ChEMBL | ChEMBL1175 Y | 1.00 | infobox |
| Duloxetine | ChEMBL | as HCl: ChEMBL1200328 Y | 1.00 | infobox |
| Duloxetine | ChemSpider | 54822 Y | 1.00 | infobox |
| Duloxetine | CompTox Dashboard (EPA) | DTXSID6048385 | 1.00 | infobox |
| Duloxetine | Drug class | Serotonin–norepinephrine reuptake inhibitor (SNRI) | 1.00 | infobox |
| Duloxetine | DrugBank | DB00476 Y | 1.00 | infobox |
| Duloxetine | ECHA InfoCard | 100.116.825 | 1.00 | infobox |
| Duloxetine | Elimination half-life | 10–12 hours | 1.00 | infobox |
| Duloxetine | Excretion | 70% in urine, 20% in feces | 1.00 | infobox |
| Duloxetine | Formula | C18H19NOS | 1.00 | infobox |
| Duloxetine | IUPHAR/BPS | 202 | 1.00 | infobox |
| Duloxetine | KEGG | D07880 Y | 1.00 | infobox |
| Duloxetine | KEGG | as HCl: D01179 Y | 1.00 | infobox |
| Duloxetine | Legal status | AU: S4 (Prescription only) | 1.00 | infobox |
| Duloxetine | Legal status | BR: Class C1 (Other controlled substances) | 1.00 | infobox |
| Duloxetine | Legal status | CA: ℞-only | 1.00 | infobox |
| Duloxetine | Legal status | UK: POM (Prescription only) | 1.00 | infobox |
| Duloxetine | Legal status | US: ℞-only | 1.00 | infobox |
| Duloxetine | Legal status | EU: Rx-only | 1.00 | infobox |
| Duloxetine | License data | US DailyMed: Duloxetine | 1.00 | infobox |
| Duloxetine | MedlinePlus | a604030 | 1.00 | infobox |
| Duloxetine | Metabolism | Liver, two P450 isozymes, CYP2D6 and CYP1A2 | 1.00 | infobox |
The concept neighborhoods around Duloxetine bring nearby vocabulary together. In this analysis, examples include Treatment, Pain and Effects. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Duloxetine, one of the stronger structural bridges in this analysis connects Duloxetine with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Duloxetine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications, Research & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Duloxetine · EN edition · Analysis: TopicsToTalkAbout
