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Ephedrine: History, Community, Culture & Applications

Ephedrine is a central nervous system (CNS) stimulant and sympathomimetic agent that is often used to prevent low blood pressure during anesthesia. It has also been used for asthma, narcolepsy, and obesity but is not the preferred treatment. It is of unclear benefit in nasal congestion. It can be taken by mouth or by injection into a muscle, vein, or…

Language: English [EN]
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Ephedrine topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Ephedrine.

Related topics
233
Source areas
11
Connected nodes
244
Extracted relationships
152
Concept neighborhoods
39
Bridge connections
244

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 73 topics
Chemistry · 36 topics
Medical uses · 34 topics
Society and culture · 24 topics
Side effects · 21 topics
Contraindications · 18 topics
Pharmacology · 9 topics
History · 8 topics
Production · 5 topics
Interactions · 3 topics
Overdose · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
Addiction liability
Moderate
AHFS/Drugs.com
Ephedrine: Monograph HCl: Monograph Sulfate: Monograph
ATC code
C01CA26 (WHO) R01AA03 (WHO), R01AB05 (WHO) (combinations), R03CA02 (WHO), S01FB02 (WHO), QG04BX90 (WHO)
Bioavailability
88%
CAS Number
299-42-3 Y 50-98-6 (hydrochloride) · as sulfate: 134-72-5 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Side effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

Production

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Ephedrine connects Entity context

The extracted context around Ephedrine shows recurring relationship patterns in the source. For example, Ephedrine → BANMTooltip British Approved Name, BANTooltip British Approved Name, DCITTooltip Denominazione Comune Italiana, Française, In, INNTooltip International Nonproprietary Name, Its DCFTooltip Dénomination Commune, JANTooltip Japanese Accepted Name, Name, The, These, USANTooltip United States Adopted Another extracted example is Ephedrine → Chemically, Ephedra, Ephedraceae, For, It, Methamphetamine, N-methyl-α-methyl-β-phenethylamine, N-methylamphetamine, OH, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ephedrine

Top relations

related to Names · 12
Ephedrine → BANMTooltip British Approved Name, BANTooltip British Approved Name, DCITTooltip Denominazione Comune Italiana, Française, In, INNTooltip International Nonproprietary Name, Its DCFTooltip Dénomination Commune, JANTooltip Japanese Accepted Name, Name, The, These, USANTooltip United States Adopted
related to Chemistry · 10
Ephedrine → Chemically, Ephedra, Ephedraceae, For, It, Methamphetamine, N-methyl-α-methyl-β-phenethylamine, N-methylamphetamine, OH, The
related to Recreational use · 9
Ephedrine → As, Because, Birch, Illicit Traffic, Moreover, Narcotic Drugs, Psychotropic Substances, The, United Nations Convention Against
related to Asia · 8
Ephedrine → AD, BC, China, Chinese, Han, In, Japanese, Nagai Nagayoshi
related to Weight loss · 8
Ephedrine → ECA, HDL, In, It, LDL, Methylxanthines, One, This
Legal status · 7
Ephedrine → AU: S4 (Prescription only), BR: Class D1 (Drug precursors), CA: Schedule VI, EU: Rx-only / OTC, SE: Rx-only, UK: POM (Prescription only) / P, US: ℞-only / OTC
related to Available forms · 7
Ephedrine → Akovaz, Corphedra, Emerphed, It, Rezipres, The, United States
related to Agricultural · 6
Ephedrine → As, China, Chinese, Ephedra, Raw, US
related to Biosynthetic · 6
Ephedrine → Benzaldehyde, CoA, L-phenylalanine, Methylation, The, This
has effect · 5
Ephedrine → ADRs, Adverse, Drug Administration, FDA, US Food

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

used use effects methamphetamine norepinephrine available drug blood united injection ephedra also oral states intravenous pseudoephedrine containing 1r mouth hydrochloride

Ephedrine relationships Subject–Predicate–Object triples

TTTA extracted 152 structured relationships around Ephedrine. Examples in this analysis include Ephedrine → 3D model (JSmol) → Interactive image and Ephedrine → Addiction liability → Moderate. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Ephedrine3D model (JSmol)Interactive image1.00infobox
EphedrineAddiction liabilityModerate1.00infobox
EphedrineAHFS/Drugs.comEphedrine: Monograph HCl: Monograph Sulfate: Monograph1.00infobox
EphedrineATC codeC01CA26 (WHO) R01AA03 (WHO), R01AB05 (WHO) (combinations), R03CA02 (WHO), S01FB02 (WHO), QG04BX90 (WHO)1.00infobox
EphedrineBioavailability88%1.00infobox
EphedrineCAS Number299-42-3 Y 50-98-6 (hydrochloride)1.00infobox
EphedrineCAS Numberas sulfate: 134-72-5 Y1.00infobox
EphedrineChEBICHEBI:15407 Y1.00infobox
EphedrineChEMBLChEMBL211456 Y1.00infobox
EphedrineChEMBLas sulfate: ChEMBL1523964 Y1.00infobox
EphedrineChemSpider8935 Y1.00infobox
EphedrineChemSpideras sulfate: 4514262 Y1.00infobox
EphedrineCompTox Dashboard (EPA)DTXSID00229851.00infobox
EphedrineDependence liabilityLow1.00infobox
EphedrineDependence liabilityPsychological: Moderate1.00infobox
EphedrineDrug classStimulant; Norepinephrine releasing agent1.00infobox
EphedrineDrugBankDB01364 Y1.00infobox
EphedrineDuration of actionOral: 2–4 hours IV/IM: 60 minutes1.00infobox
EphedrineECHA InfoCard100.005.5281.00infobox
EphedrineElimination half-life6 hours1.00infobox
EphedrineExcretionMainly urine (60% unchanged)1.00infobox
EphedrineFormulaC10H15NO1.00infobox
EphedrineIUPHAR/BPS5561.00infobox
EphedrineKEGGD00124 Y1.00infobox
EphedrineKEGGas sulfate: D04018 Y1.00infobox
EphedrineLegal statusAU: S4 (Prescription only)1.00infobox
EphedrineLegal statusBR: Class D1 (Drug precursors)1.00infobox
EphedrineLegal statusCA: Schedule VI1.00infobox
EphedrineLegal statusUK: POM (Prescription only) / P1.00infobox
EphedrineLegal statusUS: ℞-only / OTC1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Ephedrine bring nearby vocabulary together. In this analysis, examples include Used, United and States. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ephedrine
    • Used
    • United
    • States
    • Drug
    • Containing
    • Mg
    • Name
    • Traditional
    • Blood
    • Effects
    • Use
    • Chinese
  • ephedrine
    • Used
    • United
    • States
    • Drug
    • Containing
    • Mg
    • Name
    • Traditional
    • Blood
    • Effects
    • Use
    • Chinese
  • stimulant
    • Medicine
    • Pressure
    • Similar
    • Norepinephrine
    • Effects
    • Side
    • Heart
    • Loss
    • Mouth
    • Norephedrine
    • 2s
    • Chinese
  • low blood pressure
    • Pressure
    • Heart
    • Side
    • Loss
    • Stimulant
    • Effects
    • Mg
    • Similar
    • Norepinephrine
    • Drug
    • Used
    • Mouth
  • side effects
    • Side
    • Heart
    • Loss
    • Include
    • Pressure
    • Stimulant
    • Mouth
    • Similar
    • Norepinephrine
    • Norephedrine
    • Drug
    • Sulfate
  • high blood pressure
    • Pressure
    • Heart
    • Side
    • Loss
    • Stimulant
    • Effects
    • Mg
    • Similar
    • Norepinephrine
    • Drug
    • Used
    • Mouth
  • fast heart rate
    • Pressure
    • Side
    • Loss
    • Include
    • Stimulant
    • Mouth
    • Norephedrine
    • 2s
    • Hydrochloride
    • Intravenous
    • Medicine
    • Sulfate
  • heart attack
    • Pressure
    • Side
    • Loss
    • Include
    • Stimulant
    • Mouth
    • Norephedrine
    • 2s
    • Hydrochloride
    • Intravenous
    • Medicine
    • Sulfate

Connections between topic areas Semantic bridges

For Ephedrine, one of the stronger structural bridges in this analysis connects Ephedrine with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
EphedrineOverview · splits 171 ⟂ 74
EphedrineChemistry · splits 208 ⟂ 37
EphedrineMedical uses · splits 210 ⟂ 35
EphedrineSociety and culture · splits 220 ⟂ 25
EphedrineSide effects · splits 223 ⟂ 22
EphedrineContraindications · splits 226 ⟂ 19
EphedrinePharmacology · splits 235 ⟂ 10
EphedrineHistory · splits 236 ⟂ 9
EphedrineProduction · splits 239 ⟂ 6
EphedrineInteractions · splits 241 ⟂ 4
EphedrineOverdose · splits 242 ⟂ 3

Map overview Semantic statistics

Ephedrine

Nodes245
Edges244
Triples152
Avg. degree1.99
Density0.008163
Components1

Source & methodology

TTTA analyzes the structure around Ephedrine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ephedrine · EN edition · Analysis: TopicsToTalkAbout

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