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Ephedrine

Ephedrine is a central nervous system (CNS) stimulant and sympathomimetic agent that is often used to prevent low blood pressure during anesthesia. It has also been used for asthma, narcolepsy, and obesity but is not the preferred treatment. It is of unclear benefit in nasal congestion. It can be taken by mouth or by injection into a muscle, vein, or…

History, Community, Culture & Applications

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Explore the main themes, entities and connections around Ephedrine. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
Addiction liability
Moderate
AHFS/Drugs.com
Ephedrine: Monograph HCl: Monograph Sulfate: Monograph
ATC code
C01CA26 (WHO) R01AA03 (WHO), R01AB05 (WHO) (combinations), R03CA02 (WHO), S01FB02 (WHO), QG04BX90 (WHO)
Bioavailability
88%
CAS Number
299-42-3 Y 50-98-6 (hydrochloride) · as sulfate: 134-72-5 Y

Topics to explore

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Overview

Medical uses

Contraindications

Side effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

Production

Advanced semantic analysis

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Map overview Semantic statistics

Ephedrine

Nodes245
Edges244
Triples152
Avg. degree1.99
Density0.008163
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Ephedrine

Top relations

related to Names · 12
Ephedrine → BANMTooltip British Approved Name, BANTooltip British Approved Name, DCITTooltip Denominazione Comune Italiana, Française, In, INNTooltip International Nonproprietary Name, Its DCFTooltip Dénomination Commune, JANTooltip Japanese Accepted Name, Name, The, These, USANTooltip United States Adopted
related to Chemistry · 10
Ephedrine → Chemically, Ephedra, Ephedraceae, For, It, Methamphetamine, N-methyl-α-methyl-β-phenethylamine, N-methylamphetamine, OH, The
related to Recreational use · 9
Ephedrine → As, Because, Birch, Illicit Traffic, Moreover, Narcotic Drugs, Psychotropic Substances, The, United Nations Convention Against
related to Asia · 8
Ephedrine → AD, BC, China, Chinese, Han, In, Japanese, Nagai Nagayoshi
related to Weight loss · 8
Ephedrine → ECA, HDL, In, It, LDL, Methylxanthines, One, This
Legal status · 7
Ephedrine → AU: S4 (Prescription only), BR: Class D1 (Drug precursors), CA: Schedule VI, EU: Rx-only / OTC, SE: Rx-only, UK: POM (Prescription only) / P, US: ℞-only / OTC
related to Available forms · 7
Ephedrine → Akovaz, Corphedra, Emerphed, It, Rezipres, The, United States
related to Agricultural · 6
Ephedrine → As, China, Chinese, Ephedra, Raw, US
related to Biosynthetic · 6
Ephedrine → Benzaldehyde, CoA, L-phenylalanine, Methylation, The, This
has effect · 5
Ephedrine → ADRs, Adverse, Drug Administration, FDA, US Food

Important terminology Word statistics

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Important terminology

used use effects methamphetamine norepinephrine available drug blood united injection ephedra also oral states intravenous pseudoephedrine containing 1r mouth hydrochloride

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ephedrine3D model (JSmol)Interactive image1.00infobox
EphedrineAddiction liabilityModerate1.00infobox
EphedrineAHFS/Drugs.comEphedrine: Monograph HCl: Monograph Sulfate: Monograph1.00infobox
EphedrineATC codeC01CA26 (WHO) R01AA03 (WHO), R01AB05 (WHO) (combinations), R03CA02 (WHO), S01FB02 (WHO), QG04BX90 (WHO)1.00infobox
EphedrineBioavailability88%1.00infobox
EphedrineCAS Number299-42-3 Y 50-98-6 (hydrochloride)1.00infobox
EphedrineCAS Numberas sulfate: 134-72-5 Y1.00infobox
EphedrineChEBICHEBI:15407 Y1.00infobox
EphedrineChEMBLChEMBL211456 Y1.00infobox
EphedrineChEMBLas sulfate: ChEMBL1523964 Y1.00infobox
EphedrineChemSpider8935 Y1.00infobox
EphedrineChemSpideras sulfate: 4514262 Y1.00infobox
EphedrineCompTox Dashboard (EPA)DTXSID00229851.00infobox
EphedrineDependence liabilityLow1.00infobox
EphedrineDependence liabilityPsychological: Moderate1.00infobox
EphedrineDrug classStimulant; Norepinephrine releasing agent1.00infobox
EphedrineDrugBankDB01364 Y1.00infobox
EphedrineDuration of actionOral: 2–4 hours IV/IM: 60 minutes1.00infobox
EphedrineECHA InfoCard100.005.5281.00infobox
EphedrineElimination half-life6 hours1.00infobox
EphedrineExcretionMainly urine (60% unchanged)1.00infobox
EphedrineFormulaC10H15NO1.00infobox
EphedrineIUPHAR/BPS5561.00infobox
EphedrineKEGGD00124 Y1.00infobox
EphedrineKEGGas sulfate: D04018 Y1.00infobox
EphedrineLegal statusAU: S4 (Prescription only)1.00infobox
EphedrineLegal statusBR: Class D1 (Drug precursors)1.00infobox
EphedrineLegal statusCA: Schedule VI1.00infobox
EphedrineLegal statusUK: POM (Prescription only) / P1.00infobox
EphedrineLegal statusUS: ℞-only / OTC1.00infobox

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