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Warfarin: History, Applications & Art

Warfarin, sold under the brand name Coumadin among others, is used as an anticoagulant medication. It is commonly used to prevent deep vein thrombosis and pulmonary embolism, and to protect against stroke in people who have atrial fibrillation, valvular heart disease, or artificial heart valves. Warfarin may sometimes be prescribed following a ST-segment…

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Warfarin topic overview

The analysis highlights History, Applications and Art as prominent areas in the source structure around Warfarin.

Related topics
282
Source areas
9
Connected nodes
291
Extracted relationships
273
Concept neighborhoods
40
Bridge connections
291

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 105 topics
History · 37 topics
Medical uses · 31 topics
Pharmacology · 30 topics
Adverse effects · 28 topics
Interactions · 26 topics
Contraindications · 17 topics
Chemistry · 7 topics
Overdose · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
B01AA03 (WHO) QB01AA03 (WHO)
Bioavailability
79–100% (by mouth)
CAS Number
81-81-2 Y · as salt: 129-06-6
ChEBI
CHEBI:10033 Y · as salt: CHEBI:10034

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Adverse effects

Overdose

Interactions

Chemistry

Pharmacology

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Warfarin connects Entity context

The extracted context around Warfarin shows recurring relationship patterns in the source. For example, Warfarin → Aldocumar, Anasmol, Anticoag, Befarin, Cavamed, Cicoxil, Circuvit, Co-Rax, Cofarin, Con, Coumadin, Coumadine, Cov-R-Tox, Cumar, Dethmor, Farin, Foley, France, Haemofarin, Jantoven Another extracted example is Warfarin → Biotechnology Information, Bookshelf ID, CYP Genotype, Dean, Dean LC, In Pratt VM, Kattman BL, McLeod HL, Medical Genetics Summaries, National Center, NBK84174, NCBI, PMID, Rubinstein WS, Scott SA, VKORC1, Warfarin Therapy. Use these groups to spot repeated connection types before inspecting the individual relationships.

Warfarin

Top relations

related to Brand names · 64
Warfarin → Aldocumar, Anasmol, Anticoag, Befarin, Cavamed, Cicoxil, Circuvit, Co-Rax, Cofarin, Con, Coumadin, Coumadine, Cov-R-Tox, Cumar, Dethmor, Farin, Foley, France, Haemofarin, Jantoven
related to Further reading · 17
Warfarin → Biotechnology Information, Bookshelf ID, CYP Genotype, Dean, Dean LC, In Pratt VM, Kattman BL, McLeod HL, Medical Genetics Summaries, National Center, NBK84174, NCBI, PMID, Rubinstein WS, Scott SA, VKORC1, Warfarin Therapy
related to Mechanism of action · 14
Warfarin → As, Gla, II, IX, K-dependent, Other, PIVKA-II, PIVKA-number, PIVKAs, The, VII, VKOR, VKORC1, When
related to Overdose · 14
Warfarin → ABO, Administration, Blood, FFP, For, Generally, In, INR, Many, PCC, PCCs, Risk, The, While PCC
related to Pharmacokinetics · 13
Warfarin → Both, CYP-mediated, CYP2C9, CYP3A4, CYPs, Furthermore, Heparin, It, OH, R-isomer, R-warfarin, S-warfarin, Warfarin's
related to Bleeding · 12
Warfarin → All, Another, ATRIA, Bleeding, Coumadin, HAS-BLED, INR, Risk, Several, The, This, While
related to Occupational safety · 12
Warfarin → At, Community Right-to-Know Act, Emergency Planning, Health, Health Administration, It, Occupational Safety, People, Section, The National Institute, The Occupational Safety, United States
related to Pharmacogenomics · 8
Warfarin → African Americans, Asian Americans, CYP2C9, Group, INR, Polymorphisms, There, VKORC1
related to Dosing · 7
Warfarin → Dosing, During, INR, Instead, Newer, These, To
related to Interactions · 6
Warfarin → Apart, INR, NSAIDs, Some, This, When

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

vitamin inr bleeding also used may use risk effect anticoagulant many k1 blood clotting increased factors thrombosis effects several people

Warfarin relationships Subject–Predicate–Object triples

TTTA extracted 273 structured relationships around Warfarin. Examples in this analysis include Warfarin → 3D model (JSmol) → Interactive image and Warfarin → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Warfarin3D model (JSmol)Interactive image1.00infobox
WarfarinAHFS/Drugs.comMonograph1.00infobox
WarfarinATC codeB01AA03 (WHO) QB01AA03 (WHO)1.00infobox
WarfarinBioavailability79–100% (by mouth)1.00infobox
WarfarinCAS Number81-81-2 Y1.00infobox
WarfarinCAS Numberas salt: 129-06-61.00infobox
WarfarinChEBICHEBI:10033 Y1.00infobox
WarfarinChEBIas salt: CHEBI:100341.00infobox
WarfarinChEMBLChEMBL1464 N1.00infobox
WarfarinChEMBLas salt: ChEMBL12008791.00infobox
WarfarinChemSpider10442445 Y1.00infobox
WarfarinChemSpideras salt: 173331931.00infobox
WarfarinDrugBankDB00682 N1.00infobox
WarfarinDrugBankas salt: DBSALT0002781.00infobox
WarfarinECHA InfoCard100.001.2531.00infobox
WarfarinElimination half-life7 days (active half-life is 20-60 hours)1.00infobox
WarfarinExcretionKidney (92%)1.00infobox
WarfarinFormulaC19H16O41.00infobox
WarfarinIUPHAR/BPS68531.00infobox
WarfarinKEGGD08682 Y1.00infobox
WarfarinKEGGas salt: D005641.00infobox
WarfarinLegal statusAU: S4 (Prescription only)1.00infobox
WarfarinLegal statusCA: ℞-only1.00infobox
WarfarinLegal statusUK: POM (Prescription only)1.00infobox
WarfarinLegal statusUS: ℞-only1.00infobox
WarfarinLicense dataUS DailyMed: Warfarin1.00infobox
WarfarinMedlinePlusa6822771.00infobox
WarfarinMetabolismLiver: CYP2C9, 2C19, 2C8, 2C18, 1A2 and 3A41.00infobox
WarfarinMolar mass308.333 g·mol−11.00infobox
WarfarinPDB ligandRWF (PDBe, RCSB PDB)1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Warfarin bring nearby vocabulary together. In this analysis, examples include Use, Used and Effect. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Warfarin
    • Use
    • Used
    • Effect
    • Many
    • Vitamin
    • Risk
    • Also
    • Bleeding
    • Anticoagulant
    • May
    • Inr
    • Drugs
  • warfarin
    • Use
    • Used
    • Effect
    • Many
    • Vitamin
    • Risk
    • Also
    • Bleeding
    • Anticoagulant
    • May
    • Inr
    • Drugs
  • deep vein thrombosis
    • Risk
    • First
    • Days
    • Protein
    • Treatment
    • Use
    • Used
    • Pregnancy
    • Bleeding
    • Active
    • Reduced
    • Effects
  • side effect
    • Days
    • Anticoagulation
    • Warfarin
    • Clotting
    • Factors
    • Several
    • Inr
    • Reduced
    • Risk
    • Effects
    • Bleeding
    • Mg
  • major bleeding
    • Risk
    • Inr
    • People
    • Increased
    • Effects
    • Drugs
    • Time
    • Use
    • Anticoagulation
    • Commonly
    • Warfarin
    • May
  • thrombosis
    • Risk
    • First
    • Days
    • Protein
    • Treatment
    • Use
    • Used
    • Pregnancy
    • Bleeding
    • Active
    • Reduced
    • Effects
  • fetal warfarin syndrome
    • Use
    • Used
    • Effect
    • Many
    • Vitamin
    • Risk
    • Also
    • Bleeding
    • Anticoagulant
    • May
    • Inr
    • Drugs
  • deep venous thrombosis
    • Risk
    • First
    • Days
    • Protein
    • Treatment
    • Use
    • Used
    • Pregnancy
    • Bleeding
    • Active
    • Reduced
    • Effects

Connections between topic areas Semantic bridges

For Warfarin, one of the stronger structural bridges in this analysis connects Warfarin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Warfarin — Overview · splits 186 ⟂ 106
Warfarin — History · splits 254 ⟂ 38
Warfarin — Medical uses · splits 260 ⟂ 32
Warfarin — Pharmacology · splits 261 ⟂ 31
Warfarin — Adverse effects · splits 263 ⟂ 29
Warfarin — Interactions · splits 265 ⟂ 27
Warfarin — Contraindications · splits 274 ⟂ 18
Warfarin — Chemistry · splits 284 ⟂ 8

Map overview Semantic statistics

Warfarin

Nodes292
Edges291
Triples273
Avg. degree1.99
Density0.006849
Components1

Source & methodology

TTTA analyzes the structure around Warfarin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Warfarin · EN edition · Analysis: TopicsToTalkAbout

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