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Fluvastatin: Pharmacology, Interactions & Adverse effects

Fluvastatin is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease.

Language: English [EN]
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Fluvastatin topic overview

The analysis highlights Pharmacology, Interactions and Adverse effects as prominent areas in the source structure around Fluvastatin.

Related topics
24
Source areas
5
Connected nodes
29
Extracted relationships
63
Concept neighborhoods
14
Bridge connections
29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Pharmacology · 7 topics
Interactions · 6 topics
Adverse effects · 5 topics
Overview · 5 topics
Names · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C10AA04 (WHO)
Bioavailability
24–30%
CAS Number
93957-54-1 Y
ChEBI
CHEBI:38565 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Adverse effects

Interactions

Pharmacology

Names

  • INN International nonproprietary name

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Fluvastatin connects Entity context

The extracted context around Fluvastatin shows recurring relationship patterns in the source. For example, Fluvastatin → CYP2C8, CYP2C9, CYP3A4, Due, Food, N-desisopropyl, Over, P450, Several, The Another extracted example is Fluvastatin → Cholesterol Treatment Trialists, CI, CTT, Data, In, LDL, RCTs, Thus. Use these groups to spot repeated connection types before inspecting the individual relationships.

Fluvastatin

Top relations

related to Pharmacokinetics · 10
Fluvastatin → CYP2C8, CYP2C9, CYP3A4, Due, Food, N-desisopropyl, Over, P450, Several, The
related to Research · 8
Fluvastatin → Cholesterol Treatment Trialists, CI, CTT, Data, In, LDL, RCTs, Thus
Legal status · 5
Fluvastatin → AU: S4 (Prescription only), CA: ℞-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Names · 5
Fluvastatin → Brandnames, Canef, INN, Lescol, Vastin
related to Interactions · 4
Fluvastatin → Contrary, CYP2C9, CYP3A4, Fluconazole
related to Pharmacodynamics · 4
Fluvastatin → Cochrane, In, LDL, Over
3D model (JSmol) · 1
Fluvastatin → Interactive image
AHFS/Drugs.com · 1
Fluvastatin → Monograph
ATC code · 1
Fluvastatin → C10AA04 (WHO)
Bioavailability · 1
Fluvastatin → 24–30%

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cholesterol ldl 95 atorvastatin reduced myocardial infarction effects cyp2c9 cyp3a4 drug statins dose mg day interactions 24 98 names cyp2c8

Fluvastatin relationships Subject–Predicate–Object triples

TTTA extracted 63 structured relationships around Fluvastatin. Examples in this analysis include Fluvastatin → 3D model (JSmol) → Interactive image and Fluvastatin → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Fluvastatin3D model (JSmol)Interactive image1.00infobox
FluvastatinAHFS/Drugs.comMonograph1.00infobox
FluvastatinATC codeC10AA04 (WHO)1.00infobox
FluvastatinBioavailability24–30%1.00infobox
FluvastatinCAS Number93957-54-1 Y1.00infobox
FluvastatinChEBICHEBI:38565 Y1.00infobox
FluvastatinChEMBLChEMBL1078 Y1.00infobox
FluvastatinChemSpider393587 Y1.00infobox
FluvastatinCompTox Dashboard (EPA)DTXSID201020962 DTXSID2020636, DTXSID2010209621.00infobox
FluvastatinDrugBankDB01095 Y1.00infobox
FluvastatinECHA InfoCard100.224.3271.00infobox
FluvastatinElimination half-life1–3 hours (capsule), 9 hours (XR formulations)1.00infobox
FluvastatinExcretionFaeces (95%), urine (5%)1.00infobox
FluvastatinFormulaC24H26FNO41.00infobox
FluvastatinIUPHAR/BPS29511.00infobox
FluvastatinKEGGD07983 Y1.00infobox
FluvastatinLegal statusAU: S4 (Prescription only)1.00infobox
FluvastatinLegal statusCA: ℞-only1.00infobox
FluvastatinLegal statusUK: POM (Prescription only)1.00infobox
FluvastatinLegal statusUS: ℞-only1.00infobox
FluvastatinLegal statusIn general: ℞ (Prescription only)1.00infobox
FluvastatinMedlinePlusa6940101.00infobox
FluvastatinMetabolismHepatic: CYP2C9 (75%), CYP3A4 (20%), CYP2C8 (5%)1.00infobox
FluvastatinMolar mass411.473 g·mol−11.00infobox
FluvastatinPregnancy categoryAU: D1.00infobox
FluvastatinProtein binding>98%1.00infobox
FluvastatinPubChem CID4461551.00infobox
FluvastatinRoutes of administrationBy mouth (capsules, tablets)1.00infobox
FluvastatinTrade namesLescol, others1.00infobox
FluvastatinUNII4L066368AS1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Fluvastatin bring nearby vocabulary together. In this analysis, examples include Cholesterol, Cyp2c9 and Cyp3a4. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Fluvastatin
    • Cholesterol
    • Cyp2c9
    • Cyp3a4
    • Interactions
    • Atorvastatin
    • Statins
    • Infarction
    • Myocardial
    • Ldl
    • Cyp2c8
    • Drugs
    • Metabolism
  • fluvastatin
    • Cholesterol
    • Cyp2c9
    • Cyp3a4
    • Interactions
    • Atorvastatin
    • Statins
    • Infarction
    • Myocardial
    • Ldl
    • Cyp2c8
    • Drugs
    • Metabolism
  • atorvastatin
    • Infarction
    • Myocardial
    • Ldl
    • Rosuvastatin
    • Cholesterol
    • Reduced
    • Fluvastatin
    • Drugs
    • Used
    • Ci
    • Compared
    • Cyp3a4
  • adverse effects
    • Names
    • Acid
    • Bioavailability
    • Cyp2c8
    • Drugs
    • Lescol
    • Metabolism
    • Statins
    • Cyp2c9
    • Cyp3a4
    • Effects
    • Interactions
  • cholesterol
    • Ldl
    • Infarction
    • Myocardial
    • Reduced
    • Day
    • Dose
    • Mg
    • Ci
    • Compared
    • Placebo
    • Rcts
    • Relative
  • bioavailability
    • Names
    • Cyp2c8
    • Drugs
    • Lescol
    • Metabolism
    • Cyp2c9
    • Cyp3a4
    • Effects
    • Interactions
    • Statins
    • Fluvastatin
  • cyp3a4
    • Interactions
    • Statins
    • Cyp2c8
    • Drugs
    • Metabolism
    • Names
    • Fluvastatin
    • Lescol
    • Effects
    • Atorvastatin
  • cyp2c9
    • Cyp2c8
    • Metabolism
    • Cyp3a4
    • Interactions
    • Statins
    • Names
    • Fluvastatin
    • Drugs
    • Lescol
    • Effects

Connections between topic areas Semantic bridges

For Fluvastatin, one of the stronger structural bridges in this analysis connects Fluvastatin with Pharmacology. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FluvastatinPharmacology · splits 22 ⟂ 8
FluvastatinInteractions · splits 23 ⟂ 7
FluvastatinOverview · splits 24 ⟂ 6
FluvastatinAdverse effects · splits 24 ⟂ 6

Map overview Semantic statistics

Fluvastatin

Nodes30
Edges29
Triples63
Avg. degree1.93
Density0.066667
Components1

Source & methodology

TTTA analyzes the structure around Fluvastatin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Pharmacology, Interactions & Adverse effects, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Fluvastatin · EN edition · Analysis: TopicsToTalkAbout

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