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Fluvastatin

Fluvastatin is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease.

Pharmacology, Interactions & Adverse effects

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Explore the main themes, entities and connections around Fluvastatin. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C10AA04 (WHO)
Bioavailability
24–30%
CAS Number
93957-54-1 Y
ChEBI
CHEBI:38565 Y

Topics to explore

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Overview

Adverse effects

Interactions

Pharmacology

Names

  • INN International nonproprietary name

Advanced semantic analysis

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Map overview Semantic statistics

Fluvastatin

Nodes30
Edges29
Triples63
Avg. degree1.93
Density0.066667
Components1

How this topic connects Entity context

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Fluvastatin

Top relations

related to Pharmacokinetics · 10
Fluvastatin → CYP2C8, CYP2C9, CYP3A4, Due, Food, N-desisopropyl, Over, P450, Several, The
related to Research · 8
Fluvastatin → Cholesterol Treatment Trialists, CI, CTT, Data, In, LDL, RCTs, Thus
Legal status · 5
Fluvastatin → AU: S4 (Prescription only), CA: ℞-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Names · 5
Fluvastatin → Brandnames, Canef, INN, Lescol, Vastin
related to Interactions · 4
Fluvastatin → Contrary, CYP2C9, CYP3A4, Fluconazole
related to Pharmacodynamics · 4
Fluvastatin → Cochrane, In, LDL, Over
3D model (JSmol) · 1
Fluvastatin → Interactive image
AHFS/Drugs.com · 1
Fluvastatin → Monograph
ATC code · 1
Fluvastatin → C10AA04 (WHO)
Bioavailability · 1
Fluvastatin → 24–30%

Important terminology Word statistics

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Important terminology

cholesterol ldl 95 atorvastatin reduced myocardial infarction effects cyp2c9 cyp3a4 drug statins dose mg day interactions 24 98 names cyp2c8

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Fluvastatin3D model (JSmol)Interactive image1.00infobox
FluvastatinAHFS/Drugs.comMonograph1.00infobox
FluvastatinATC codeC10AA04 (WHO)1.00infobox
FluvastatinBioavailability24–30%1.00infobox
FluvastatinCAS Number93957-54-1 Y1.00infobox
FluvastatinChEBICHEBI:38565 Y1.00infobox
FluvastatinChEMBLChEMBL1078 Y1.00infobox
FluvastatinChemSpider393587 Y1.00infobox
FluvastatinCompTox Dashboard (EPA)DTXSID201020962 DTXSID2020636, DTXSID2010209621.00infobox
FluvastatinDrugBankDB01095 Y1.00infobox
FluvastatinECHA InfoCard100.224.3271.00infobox
FluvastatinElimination half-life1–3 hours (capsule), 9 hours (XR formulations)1.00infobox
FluvastatinExcretionFaeces (95%), urine (5%)1.00infobox
FluvastatinFormulaC24H26FNO41.00infobox
FluvastatinIUPHAR/BPS29511.00infobox
FluvastatinKEGGD07983 Y1.00infobox
FluvastatinLegal statusAU: S4 (Prescription only)1.00infobox
FluvastatinLegal statusCA: ℞-only1.00infobox
FluvastatinLegal statusUK: POM (Prescription only)1.00infobox
FluvastatinLegal statusUS: ℞-only1.00infobox
FluvastatinLegal statusIn general: ℞ (Prescription only)1.00infobox
FluvastatinMedlinePlusa6940101.00infobox
FluvastatinMetabolismHepatic: CYP2C9 (75%), CYP3A4 (20%), CYP2C8 (5%)1.00infobox
FluvastatinMolar mass411.473 g·mol−11.00infobox
FluvastatinPregnancy categoryAU: D1.00infobox
FluvastatinProtein binding>98%1.00infobox
FluvastatinPubChem CID4461551.00infobox
FluvastatinRoutes of administrationBy mouth (capsules, tablets)1.00infobox
FluvastatinTrade namesLescol, others1.00infobox
FluvastatinUNII4L066368AS1.00infobox

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