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Naproxen: Community, Culture, Applications & Research

Naproxen, sold under the brand name Aleve among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, and inflammatory diseases such as rheumatoid arthritis, gout and fever. It is taken orally. It is available in immediate and delayed release formulations. Onset of effects is within an hour and lasts for up to…

Language: English [EN]
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Naproxen topic overview

The analysis highlights Community, Culture, Applications and Research as prominent areas in the source structure around Naproxen.

Related topics
106
Source areas
10
Connected nodes
116
Extracted relationships
161
Concept neighborhoods
32
Bridge connections
116

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 26 topics
Adverse effects · 19 topics
Pharmacology · 14 topics
Drug-drug interactions · 12 topics
Medical uses · 11 topics
Society and culture · 11 topics
Chemistry · 6 topics
Veterinary use · 4 topics
Ecological effects · 2 topics
Research · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
G02CC02 (WHO) M01AE02 (WHO), M02AA12 (WHO), M01AE56 (WHO), M01AE52 (WHO)
Bioavailability
100% (by mouth)
CAS Number
22204-53-1 Y
ChEBI
CHEBI:7476 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Drug-drug interactions

Pharmacology

Chemistry

Society and culture

Ecological effects

Research

Veterinary use

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Naproxen connects Entity context

The extracted context around Naproxen shows recurring relationship patterns in the source. For example, Naproxen → Aleve, Anaprox, Bayer HealthCare, British Columbia, Canada, Drug Administration, FDA, Feminax Ultra, Food, In, In Australia, It, January, July, Labrador, Naprosyn, Netherlands, Newfoundland, OTC, Quebec Another extracted example is Naproxen → Accord, Aleve, Anaprox, Antalgin, Apranax, Eox, Feminax Ultra, Flanax, Inza, It, Maxidol, Nalgesin, Naposin, Naprelan, Naprogesic, Naprosyn, Narocin, Pronaxen, Proxen, Soproxen. Use these groups to spot repeated connection types before inspecting the individual relationships.

Naproxen

Top relations

related to Access restrictions · 25
Naproxen → Aleve, Anaprox, Bayer HealthCare, British Columbia, Canada, Drug Administration, FDA, Feminax Ultra, Food, In, In Australia, It, January, July, Labrador, Naprosyn, Netherlands, Newfoundland, OTC, Quebec
related to Brand names · 22
Naproxen → Accord, Aleve, Anaprox, Antalgin, Apranax, Eox, Feminax Ultra, Flanax, Inza, It, Maxidol, Nalgesin, Naposin, Naprelan, Naprogesic, Naprosyn, Narocin, Pronaxen, Proxen, Soproxen
has effect · 10
Naproxen → Although, Common, Drug Administration, FDA, Food, Heavy, In October, NSAIDs, Some, They
related to Cardiovascular · 8
Naproxen → Cardiovascular, Conversely, COX-1, COX-2, CVD, NSAID, NSAIDs, The
related to Pharmacogenetics · 7
Naproxen → CYP2C9, However, In, NSAID-induced, PK, Studies, The
related to Gastrointestinal · 6
Naproxen → As, COX-2, In, NSAIDs, Persons, To
related to Drug-drug interactions · 5
Naproxen → Alcohol, NSAIDs, SSRI, SSRIs, The
related to Pharmacokinetics · 5
Naproxen → An, CYP1A2, CYP2C9, It, O-desmethylnaproxen
Legal status · 4
Naproxen → AU: S2 (Pharmacy medicine) when in preparations that contain no more than 15 days' supply. Otherwise it is Schedule 4 (Prescription only)., CA: OTC / Rx-only, UK: POM (Prescription only) / P, US: OTC / Rx-only
related to Available formulations · 4
Naproxen → Extended-release, Imprint L490, Round, The

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

risk nsaids effects gastrointestinal available pain sodium anti-inflammatory use brand nsaid drug disease united name ulcers pregnancy mg bleeding may

Naproxen relationships Subject–Predicate–Object triples

TTTA extracted 161 structured relationships around Naproxen. Examples in this analysis include Naproxen → 3D model (JSmol) → Interactive image and Naproxen → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Naproxen3D model (JSmol)Interactive image1.00infobox
NaproxenAHFS/Drugs.comMonograph1.00infobox
NaproxenATC codeG02CC02 (WHO) M01AE02 (WHO), M02AA12 (WHO), M01AE56 (WHO), M01AE52 (WHO)1.00infobox
NaproxenBioavailability100% (by mouth)1.00infobox
NaproxenCAS Number22204-53-1 Y1.00infobox
NaproxenChEBICHEBI:7476 Y1.00infobox
NaproxenChEMBLChEMBL154 Y1.00infobox
NaproxenChemSpider137720 Y1.00infobox
NaproxenCompTox Dashboard (EPA)DTXSID40406861.00infobox
NaproxenDrugBankDB00788 Y1.00infobox
NaproxenDuration of action12 hours1.00infobox
NaproxenECHA InfoCard100.040.7471.00infobox
NaproxenElimination half-life14 hours (adults)1.00infobox
NaproxenExcretionKidney1.00infobox
NaproxenFormulaC14H14O31.00infobox
NaproxenKEGGD00118 Y1.00infobox
NaproxenKEGGas salt: D00970 Y1.00infobox
NaproxenLegal statusAU: S2 (Pharmacy medicine) when in preparations that contain no more than 15 days' supply. Otherwise it is Schedule 4 (Prescription only).1.00infobox
NaproxenLegal statusCA: OTC / Rx-only1.00infobox
NaproxenLegal statusUK: POM (Prescription only) / P1.00infobox
NaproxenLegal statusUS: OTC / Rx-only1.00infobox
NaproxenLicense dataUS DailyMed: Naproxen1.00infobox
NaproxenMedlinePlusa6810291.00infobox
NaproxenMelting point152–154 °C (306–309 °F)1.00infobox
NaproxenMetabolismLiver (to 6-desmethylnaproxen)1.00infobox
NaproxenMolar mass230.263 g·mol−11.00infobox
NaproxenOnset of action1 hour1.00infobox
NaproxenPDB ligandNPX (PDBe, RCSB PDB)1.00infobox
NaproxenPregnancy categoryAU: C1.00infobox
NaproxenPronunciation/nəˈprɒksən/1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Naproxen bring nearby vocabulary together. In this analysis, examples include Sodium, Gastrointestinal and Risk. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Naproxen
    • Sodium
    • Gastrointestinal
    • Risk
    • Mg
    • Effects
    • Nsaids
    • Adverse
    • Bleeding
    • Use
    • Inflammatory
    • Medications
    • Nsaid
  • naproxen
    • Sodium
    • Gastrointestinal
    • Risk
    • Mg
    • Effects
    • Nsaids
    • Adverse
    • Bleeding
    • Use
    • Inflammatory
    • Medications
    • Nsaid
  • brand names
    • Name
    • Aleve
    • Tablets
    • Formulations
    • Otc
    • Mg
    • Available
    • Naproxen
    • Sodium
    • Action
    • Medical
    • Pregnancy
  • naproxen/esomeprazole magnesium
    • Sodium
    • Gastrointestinal
    • Risk
    • Mg
    • Effects
    • Nsaids
    • Adverse
    • Bleeding
    • Use
    • Inflammatory
    • Medications
    • Nsaid
  • store brand
    • Name
    • Aleve
    • Tablets
    • Formulations
    • Otc
    • Mg
    • Available
    • Naproxen
    • Sodium
    • Action
    • Medical
    • Pregnancy
  • adverse effects
    • Adverse
    • Effects
    • Gastrointestinal
    • Cardiovascular
    • Stomach
    • Disease
    • Risk
    • Naproxen
    • Medical
    • Medication
    • Pregnancy
    • Aleve
  • veterinary use
    • Pregnancy
    • Medical
    • Medications
    • Action
    • Naproxen
    • States
    • Aleve
    • Associated
    • Cardiovascular
    • Formulations
    • Kidney
    • Needed
  • nonsteroidal anti-inflammatory drug
    • Inflammatory
    • Kidney
    • Drug
    • Pain
    • Action
    • Used
    • Medications
    • Nsaid
    • Name
    • Risk
    • States
    • Associated

Connections between topic areas Semantic bridges

For Naproxen, one of the stronger structural bridges in this analysis connects Naproxen with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NaproxenOverview · splits 90 ⟂ 27
NaproxenAdverse effects · splits 97 ⟂ 20
NaproxenPharmacology · splits 102 ⟂ 15
NaproxenDrug-drug interactions · splits 104 ⟂ 13
NaproxenMedical uses · splits 105 ⟂ 12
NaproxenSociety and culture · splits 105 ⟂ 12
NaproxenChemistry · splits 110 ⟂ 7
NaproxenVeterinary use · splits 112 ⟂ 5
NaproxenEcological effects · splits 114 ⟂ 3

Map overview Semantic statistics

Naproxen

Nodes117
Edges116
Triples161
Avg. degree1.98
Density0.017094
Components1

Source & methodology

TTTA analyzes the structure around Naproxen to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Community, Culture, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Naproxen · EN edition · Analysis: TopicsToTalkAbout

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