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Ranitidine: History, Applications, Products & Standards

Ranitidine, sold under the brand name Zantac among others, is a medication used to decrease stomach acid production. It is used in the treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. It can be given by mouth, injection into a muscle, or injection into a vein.

Language: English [EN]
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Ranitidine topic overview

The analysis highlights History, Applications, Products and Standards as prominent areas in the source structure around Ranitidine.

Related topics
103
Source areas
7
Connected nodes
110
Extracted relationships
155
Concept neighborhoods
23
Bridge connections
110

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 38 topics
Adverse effects · 18 topics
Precautions · 17 topics
History · 16 topics
Medical uses · 11 topics
Pharmacology · 2 topics
Preparations · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A02BA02 (WHO) A02BA07 (WHO) (ranitidine bismuth citrate)
Bioavailability
50% (by mouth)
CAS Number
66357-35-5 · HCl: 66357-59-3
ChEBI
CHEBI:8776 · HCl: CHEBI:8777

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Precautions

Pharmacology

History

Preparations

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Ranitidine connects Entity context

The extracted context around Ranitidine shows recurring relationship patterns in the source. For example, Ranitidine → AH19065, Allen, Both, CYP450, England, French, Glaxo, Glaxo Group Research, Glaxo Wellcome, GlaxoSmithKline, GSK, H2, Hanbury's Ltd, Hanburys, Its, John Bradshaw, Kline, November, Sir James Black, Smith Another extracted example is Ranitidine → Apotex Inc, Canada, Drug Administration, EMA, European Commission, European Union-wide, FDA, Health Canada, In June, In September, N-nitrosodimethylamine, NDMA, Pro Doc Limitée, Sandoz Canada, Sanis Health Inc, Sivem Pharmaceuticals ULC, The European Medicines Agency, US Food, Valisure, Zantac. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ranitidine

Top relations

related to history · 24
Ranitidine → AH19065, Allen, Both, CYP450, England, French, Glaxo, Glaxo Group Research, Glaxo Wellcome, GlaxoSmithKline, GSK, H2, Hanbury's Ltd, Hanburys, Its, John Bradshaw, Kline, November, Sir James Black, Smith
related to Cancer-causing due to inherent instability · 21
Ranitidine → Apotex Inc, Canada, Drug Administration, EMA, European Commission, European Union-wide, FDA, Health Canada, In June, In September, N-nitrosodimethylamine, NDMA, Pro Doc Limitée, Sandoz Canada, Sanis Health Inc, Sivem Pharmaceuticals ULC, The European Medicines Agency, US Food, Valisure, Zantac
related to Medical uses · 16
Ranitidine → Ellison, Erosive, GERD, GI, GORD, Helicobacter, In, NSAID-induced, NSAIDs, Pathologic, PPIs, Prevention, Proton-pump, Relief, The, Zollinger
related to Gastrointestinal · 9
Ranitidine → B12, Drugs, Elderly, Even, GI, H2, IgE, In, Patients
related to Preparations · 8
Ranitidine → In, In Australia, In India, Larger, OTC, Preparations, United Kingdom, United States
related to Mechanism of action · 5
Ranitidine → Additional, H2, In, Ranitidine's, This
Legal status · 4
Ranitidine → AU: S4 (Prescription only) / S2 (Pharmacy Medicine), CA: ℞-only / OTC, EU: Rx-only, US: ℞-only / OTC
related to Children · 3
Ranitidine → H2, In, VLBW
related to Disease-related concerns · 3
Ranitidine → In, It, Relief
CAS Number · 2
Ranitidine → 66357-35-5, HCl: 66357-59-3

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ndma 2019 may drug medicines products h2 fda united levels found 2020 risk states receptor recalled effects drugs issued zantac

Ranitidine relationships Subject–Predicate–Object triples

TTTA extracted 155 structured relationships around Ranitidine. Examples in this analysis include Ranitidine → 3D model (JSmol) → Interactive image and Ranitidine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Ranitidine3D model (JSmol)Interactive image1.00infobox
RanitidineAHFS/Drugs.comMonograph1.00infobox
RanitidineATC codeA02BA02 (WHO) A02BA07 (WHO) (ranitidine bismuth citrate)1.00infobox
RanitidineBioavailability50% (by mouth)1.00infobox
RanitidineCAS Number66357-35-51.00infobox
RanitidineCAS NumberHCl: 66357-59-31.00infobox
RanitidineChEBICHEBI:87761.00infobox
RanitidineChEBIHCl: CHEBI:87771.00infobox
RanitidineChEMBLChEMBL17900411.00infobox
RanitidineChEMBLHCl: ChEMBL21103721.00infobox
RanitidineChemSpider48631.00infobox
RanitidineChemSpiderHCl: 435901.00infobox
RanitidineCompTox Dashboard (EPA)DTXSID80451911.00infobox
RanitidineDrug classHistamine H2 receptor antagonist, aka H2 blocker1.00infobox
RanitidineDrugBankDB008631.00infobox
RanitidineDrugBankHCl: DBSALT0004871.00infobox
RanitidineECHA InfoCard100.060.2831.00infobox
RanitidineElimination half-life2–3 hours1.00infobox
RanitidineExcretion30–70% kidney1.00infobox
RanitidineFormulaC13H22N4O3S1.00infobox
RanitidineIUPHAR/BPS12341.00infobox
RanitidineKEGGD004221.00infobox
RanitidineKEGGHCl: D006731.00infobox
RanitidineLegal statusAU: S4 (Prescription only) / S2 (Pharmacy Medicine)1.00infobox
RanitidineLegal statusCA: ℞-only / OTC1.00infobox
RanitidineLegal statusUS: ℞-only / OTC1.00infobox
RanitidineLegal statusEU: Rx-only1.00infobox
RanitidineLicense dataUS DailyMed: Ranitidine1.00infobox
RanitidineMedlinePlusa6011061.00infobox
RanitidineMetabolismLiver: FMOs, including FMO3; other enzymes1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Ranitidine bring nearby vocabulary together. In this analysis, examples include Ndma, Products and Recalled. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ranitidine
    • Ndma
    • Products
    • Recalled
    • Levels
    • Drug
    • Testing
    • States
    • United
    • Fda
    • Medicines
    • Found
    • H2
  • ranitidine
    • Ndma
    • Products
    • Recalled
    • Levels
    • Drug
    • Testing
    • States
    • United
    • Fda
    • Medicines
    • Found
    • H2
  • medicines and healthcare products regulatory agency
    • Levels
    • Available
    • September
    • Medicines
    • Products
    • Issued
    • Ranitidine
    • Fda
    • Ndma
    • Include
    • Australia
    • European
  • committee for medicinal products for human use
    • Available
    • September
    • Medicines
    • Reported
    • Issued
    • Ranitidine
    • Gastric
    • Levels
    • Risk
    • Fda
    • Include
    • Australia
  • world health organization's list of essential medicines
    • Recalled
    • Levels
    • Products
    • Tablets
    • Ndma
    • Ranitidine
    • September
    • Use
    • Issued
    • States
    • United
    • Available
  • european medicines agency
    • Medicines
    • Levels
    • Products
    • Ndma
    • Ranitidine
    • September
    • Use
    • Issued
    • States
    • Australia
    • Due
    • United
  • food and drug administration
    • Due
    • Drugs
    • Found
    • Liver
    • Ranitidine
    • May
    • Gastric
    • Risk
    • Histamine
    • Zantac
    • Effects
    • Patients
  • adverse drug reactions
    • Due
    • Drugs
    • Found
    • Liver
    • Ranitidine
    • May
    • Gastric
    • Risk
    • Histamine
    • Zantac
    • Effects
    • Patients

Connections between topic areas Semantic bridges

For Ranitidine, one of the stronger structural bridges in this analysis connects Ranitidine with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
RanitidineOverview · splits 72 ⟂ 39
RanitidineAdverse effects · splits 92 ⟂ 19
RanitidinePrecautions · splits 93 ⟂ 18
RanitidineHistory · splits 94 ⟂ 17
RanitidineMedical uses · splits 99 ⟂ 12
RanitidinePharmacology · splits 108 ⟂ 3

Map overview Semantic statistics

Ranitidine

Nodes111
Edges110
Triples155
Avg. degree1.98
Density0.018018
Components1

Source & methodology

TTTA analyzes the structure around Ranitidine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications, Products & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ranitidine · EN edition · Analysis: TopicsToTalkAbout

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